Related papers: Topological Signal Processing Over Cell MultiCompl…
Persistent topological Laplacians constitute a new class of tools in topological data analysis (TDA). They are motivated by the necessity to address challenges encountered in persistent homology when handling complex data. These Laplacians…
Complex systems are difficult to study not only because they are nonlinear, multiscale, and often nonstationary, but because their scientifically relevant organization is often invisible at the level of individual components, pairwise…
Deep learning methods have achieved impressive performance for multi-class medical image segmentation. However, they are limited in their ability to encode topological interactions among different classes (e.g., containment and exclusion).…
Convolutional neural networks are nowadays witnessing a major success in different pattern recognition problems. These learning models were basically designed to handle vectorial data such as images but their extension to non-vectorial and…
Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…
Graph-based signal processing techniques have become essential for handling data in non-Euclidean spaces. However, there is a growing awareness that these graph models might need to be expanded into `higher-order' domains to effectively…
In multicellular organisms, cells coordinate their activities through cell-cell communication (CCC), which is crucial for development, tissue homeostasis, and disease progression. Recent advances in single-cell and spatial omics…
Network representations often cannot fully account for the structural richness of complex systems spanning multiple levels of organisation. Recently proposed high-order information-theoretic signals are well-suited to capture synergistic…
Higher-order networks can sustain topological signals which are variables associated not only to the nodes, but also to the links, to the triangles and in general to the higher dimensional simplices of simplicial complexes. These…
Cognitive map learners (CML) are a collection of separate yet collaboratively trained single-layer artificial neural networks (matrices), which navigate an abstract graph by learning internal representations of the node states, edge…
Higher-order networks encode the many-body interactions existing in complex systems, such as the brain, protein complexes, and social interactions. Simplicial complexes are higher-order networks that allow a comprehensive investigation of…
Graph Signal Processing deals with the problem of analyzing and processing signals defined on graphs. In this paper, we introduce a novel filtering method for graph-based signals by employing ideas from topological data analysis. We begin…
Simplicial complexes capture the underlying network topology and geometry of complex systems ranging from the brain to social networks. Here we show that algebraic topology is a fundamental tool to capture the higher-order dynamics of…
Neural networks encode inputs as high-dimensional vectors, known as representations, that capture how models process data by encoding task-relevant structure and semantics. Representation alignment refers to the degree to which different…
The construction of a meaningful graph plays a crucial role in the success of many graph-based representations and algorithms for handling structured data, especially in the emerging field of graph signal processing. However, a meaningful…
Recent advances in cellular research demonstrate that scRNA-seq characterizes cellular heterogeneity, while spatial transcriptomics reveals the spatial distribution of gene expression. Cell representation is the fundamental issue in the two…
Graphs are ubiquitous to model the irregular (non-Euclidean) structure of complex data, but they are limited to pairwise relationships and fail to model the complexities of the datasets exhibiting higher-order interactions. In that context,…
Traditionally, interaction systems have been described as networks, where links encode information on the pairwise influences among the nodes. Yet, in many systems, interactions take place in larger groups. Recent work has shown that…
Hypergraphs are useful mathematical models for describing complex relationships among members of a structured graph, while hyperdigraphs serve as a generalization that can encode asymmetric relationships in the data. However, obtaining…
In artificial-intelligence-aided signal processing, existing deep learning models often exhibit a black-box structure, and their validity and comprehensibility remain elusive. The integration of topological methods, despite its relatively…