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The integration of Large Language Models (LLMs) into the public health policy sector offers a transformative approach to navigating the vast repositories of regulatory guidance maintained by agencies such as the Centers for Disease Control…

Computation and Language · Computer Science 2026-01-23 Anuj Maharjan , Umesh Yadav

Large language models (LLMs) typically utilize the top-k contexts from a retriever in retrieval-augmented generation (RAG). In this work, we propose a novel instruction fine-tuning framework RankRAG, which instruction-tunes a single LLM for…

Computation and Language · Computer Science 2024-07-03 Yue Yu , Wei Ping , Zihan Liu , Boxin Wang , Jiaxuan You , Chao Zhang , Mohammad Shoeybi , Bryan Catanzaro

Asynchronous patient-clinician messaging via EHR portals is a growing source of clinician workload, prompting interest in large language models (LLMs) to assist with draft responses. However, LLM outputs may contain clinical inaccuracies,…

Computation and Language · Computer Science 2025-09-29 Wenyuan Chen , Fateme Nateghi Haredasht , Kameron C. Black , Francois Grolleau , Emily Alsentzer , Jonathan H. Chen , Stephen P. Ma

Recent advances in large language models (LLMs) have led to impressive progress in natural language generation, yet their tendency to produce hallucinated or unsubstantiated content remains a critical concern. To improve factual…

Computation and Language · Computer Science 2025-05-20 Xukai Liu , Ye Liu , Shiwen Wu , Yanghai Zhang , Yihao Yuan , Kai Zhang , Qi Liu

Retrieval-augmented generation (RAG) is a promising approach to address the limitations of fixed knowledge in large language models (LLMs). However, current benchmarks for evaluating RAG systems suffer from two key deficiencies: (1) they…

Computation and Language · Computer Science 2025-01-28 Zehan Qi , Rongwu Xu , Zhijiang Guo , Cunxiang Wang , Hao Zhang , Wei Xu

Deploying Large Language Models (LLMs) for healthcare question answering requires robust methods to ensure accuracy and reliability. This work introduces Query-Based Retrieval Augmented Generation (QB-RAG), a framework for enhancing…

Machine Learning · Computer Science 2025-07-31 Eric Yang , Jonathan Amar , Jong Ha Lee , Bhawesh Kumar , Yugang Jia

This paper presents OG-RAG, an Ontology-Grounded Retrieval Augmented Generation method designed to enhance LLM-generated responses by anchoring retrieval processes in domain-specific ontologies. While LLMs are widely used for tasks like…

Computation and Language · Computer Science 2024-12-23 Kartik Sharma , Peeyush Kumar , Yunqing Li

Large language models (LLMs) achieve optimal utility when their responses are grounded in external knowledge sources. However, real-world documents, such as annual reports, scientific papers, and clinical guidelines, frequently combine…

Information Retrieval · Computer Science 2025-12-17 Chi Zhang , Qiyang Chen , Mengqi Zhang

Medical retrieval-augmented generation (RAG) systems typically operate on text chunks extracted from biomedical literature, discarding the rich visual content (tables, figures, structured layouts) of original document pages. We propose…

Artificial Intelligence · Computer Science 2026-05-01 Xupeng Chen , Binbin Shi , Chenqian Le , Jiaqi Zhang , Kewen Wang , Ran Gong , Jinhan Zhang , Chihang Wang

Despite their remarkable capabilities, large language models (LLMs) often produce responses containing factual inaccuracies due to their sole reliance on the parametric knowledge they encapsulate. Retrieval-Augmented Generation (RAG), an ad…

Computation and Language · Computer Science 2023-10-19 Akari Asai , Zeqiu Wu , Yizhong Wang , Avirup Sil , Hannaneh Hajishirzi

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Multi-modal Retrieval-Augmented Generation (RAG) has become a critical method for empowering LLMs by leveraging candidate visual documents. However, current methods consider the entire document as the basic retrieval unit, introducing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Yinglu Li , Zhiying Lu , Zhihang Liu , Yiwei Sun , Chuanbin Liu , Hongtao Xie

Large language models (LLMs) have transformed various sectors, including education, finance, and medicine, by enhancing content generation and decision-making processes. However, their integration into the medical field is cautious due to…

Information Retrieval · Computer Science 2025-04-15 Yifan Feng , Hao Hu , Xingliang Hou , Shiquan Liu , Shihui Ying , Shaoyi Du , Han Hu , Yue Gao

Large language models (LLMs) exhibit remarkable generative capabilities but often suffer from hallucinations. Retrieval-augmented generation (RAG) offers an effective solution by incorporating external knowledge, but existing methods still…

Computation and Language · Computer Science 2024-12-17 Xiaoxi Li , Jiajie Jin , Yujia Zhou , Yongkang Wu , Zhonghua Li , Qi Ye , Zhicheng Dou

Large Vision-Language Models (LVLMs) have made remarkable strides in multimodal tasks such as visual question answering, visual grounding, and complex reasoning. However, they remain limited by static training data, susceptibility to…

Artificial Intelligence · Computer Science 2025-08-27 Chan-Wei Hu , Yueqi Wang , Shuo Xing , Chia-Ju Chen , Suofei Feng , Ryan Rossi , Zhengzhong Tu

Retrieval-Augmented Generation (RAG) integrates non-parametric knowledge into Large Language Models (LLMs), typically from unstructured texts and structured graphs. While recent progress has advanced text-based RAG to multi-turn reasoning…

Computation and Language · Computer Science 2025-12-11 Yucan Guo , Miao Su , Saiping Guan , Zihao Sun , Xiaolong Jin , Jiafeng Guo , Xueqi Cheng

Retrieval-Augmented Generation (RAG) enhances Large Language Models (LLMs) by integrating them with an external knowledge base to improve the answer relevance and accuracy. In real-world scenarios, beyond pure text, a substantial amount of…

Computation and Language · Computer Science 2025-10-07 Jiaru Zou , Dongqi Fu , Sirui Chen , Xinrui He , Zihao Li , Yada Zhu , Jiawei Han , Jingrui He

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Large Language Models (LLMs) demonstrate human-level capabilities in dialogue, reasoning, and knowledge retention. However, even the most advanced LLMs face challenges such as hallucinations and real-time updating of their knowledge.…

Computation and Language · Computer Science 2024-09-10 Xuanwang Zhang , Yunze Song , Yidong Wang , Shuyun Tang , Xinfeng Li , Zhengran Zeng , Zhen Wu , Wei Ye , Wenyuan Xu , Yue Zhang , Xinyu Dai , Shikun Zhang , Qingsong Wen

Recently, Retrieval-Augmented Generation (RAG) has achieved remarkable success in addressing the challenges of Large Language Models (LLMs) without necessitating retraining. By referencing an external knowledge base, RAG refines LLM…

Artificial Intelligence · Computer Science 2024-09-11 Boci Peng , Yun Zhu , Yongchao Liu , Xiaohe Bo , Haizhou Shi , Chuntao Hong , Yan Zhang , Siliang Tang