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This paper introduces Agentic-AI Healthcare, a privacy-aware, multilingual, and explainable research prototype developed as a single-investigator project. The system leverages the emerging Model Context Protocol (MCP) to orchestrate…

Cryptography and Security · Computer Science 2025-10-06 Mohammed A. Shehab

With the rise of Large Language Models (LLMs), notably characterized by GPT frameworks, there emerges a catalyst for novel healthcare applications. Earlier iterations of chatbot caregivers, though existent, have yet to achieve a dimension…

Computation and Language · Computer Science 2023-11-28 Lifei Zheng , Yeonie Heo , Yi Fang

The development of artificial intelligence systems is transitioning from creating static, task-specific models to dynamic, agent-based systems capable of performing well in a wide range of applications. We propose an Interactive Agent…

We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

Machine Learning · Computer Science 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase

Multimodal neuroimaging analysis often involves complex, modality-specific preprocessing workflows that require careful configuration, quality control, and coordination across heterogeneous toolchains. Beyond preprocessing, downstream…

Artificial Intelligence · Computer Science 2026-05-08 Lujia Zhong , Yihao Xia , Jianwei Zhang , Shuo huang , Jiaxin Yue , Mingyang Xia , Yonggang Shi

Alzheimer's disease (AD) diagnosis is complex, requiring the integration of imaging and clinical data for accurate assessment. While deep learning has shown promise in brain MRI analysis, it often functions as a black box, limiting…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Yexiao He , Ziyao Wang , Yuning Zhang , Tingting Dan , Tianlong Chen , Guorong Wu , Ang Li

Agentic AI represents a transformative shift in artificial intelligence, but its rapid advancement has led to a fragmented understanding, often conflating modern neural systems with outdated symbolic models -- a practice known as conceptual…

Artificial Intelligence · Computer Science 2025-10-30 Mohamad Abou Ali , Fadi Dornaika

Although artificial intelligence (AI) agents are increasingly proposed to support potentially longitudinal health tasks, such as symptom management, behavior change, and patient support, most current implementations fall short of…

Artificial Intelligence · Computer Science 2026-04-30 Georgianna Lin , Rencong Jiang , Noémie Elhadad , Xuhai "Orson" Xu

Alzheimer's disease (AD) is the most prevalent neurodegenerative disease; yet its currently available treatments are limited to stopping disease progression. Moreover, effectiveness of these treatments is not guaranteed due to the…

Machine Learning · Computer Science 2024-02-02 Diego Machado Reyes , Hanqing Chao , Juergen Hahn , Li Shen , Pingkun Yan

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

Telecom networks are rapidly growing in scale and complexity, making effective management, operation, and optimization increasingly challenging. Although Artificial Intelligence (AI) has been applied to many telecom tasks, existing models…

Artificial Intelligence · Computer Science 2025-11-04 Chenhua Shi , Bhavika Jalli , Gregor Macdonald , John Zou , Wanlu Lei , Mridul Jain , Joji Philip

Machine learning approaches for Alzheimer's disease (AD) diagnosis face a fundamental challenges. Clinical assessments are expensive and invasive, leaving ground truth labels available for only a fraction of neuroimaging datasets. We…

Machine Learning · Computer Science 2026-03-23 Alireza Moayedikia , Sara Fin

Dementia is a progressive cognitive syndrome with Alzheimer's disease (AD) as the leading cause. Conversation-based AD detection offers a cost-effective alternative to clinical methods, as language dysfunction is an early biomarker of AD.…

Computation and Language · Computer Science 2025-02-27 Arezo Shakeri , Mina Farmanbar , Krisztian Balog

Mild Cognitive Impairment (MCI) serves as a prodromal stage of Alzheimer's Disease (AD), where early identification and intervention can effectively slow the progression to dementia. However, diagnosing AD remains a significant challenge in…

Artificial Intelligence · Computer Science 2025-11-07 Yutao Jin , Haowen Xiao , Junyong Zhai , Yuxiao Li , Jielei Chu , Fengmao Lv , Yuxiao Li

Early diagnosis of Alzheimer's disease and related dementias (ADRD) is critical for timely intervention, yet most diagnoses are delayed until advanced stages. While comprehensive patient narratives are essential for accurate diagnosis,…

Human-Computer Interaction · Computer Science 2026-01-28 Andrew G. Breithaupt , Nayoung Choi , James D. Finch , Jeanne M. Powell , Arin L. Nelson , Oz A. Alon , Howard J. Rosen , Jinho D. Choi

Agentic AI represents a new paradigm for automating complex systems by using Large AI Models (LAMs) to provide human-level cognitive abilities with multimodal perception, planning, memory, and reasoning capabilities. This will lead to a new…

Artificial Intelligence · Computer Science 2025-11-05 Jorge Pellejero , Luis A. Hernández Gómez , Luis Mendo Tomás , Zoraida Frias Barroso

Alzheimer's disease (AD) persists as a paramount challenge in neurological research, characterized by the pathological hallmarks of amyloid-beta (Abeta) plaques and neurofibrillary tangles composed of hyperphosphorylated tau. This review…

Neurons and Cognition · Quantitative Biology 2025-12-15 Xutong She

Healthcare organizations are beginning to embed agentic AI into routine workflows, including clinical documentation support and early-warning monitoring. As these capabilities diffuse across departments and vendors, health systems face…

Artificial Intelligence · Computer Science 2026-05-19 Chandra Prakash , Mary Lind , Avneesh Sisodia

Automated Alzheimer's Disease (AD) screening has predominantly followed the inductive paradigm of pattern recognition, which directly maps the input signal to the outcome label. This paradigm sacrifices construct validity of clinical…

Multiagent Systems · Computer Science 2026-03-19 Jiawen Kang , Kun Li , Dongrui Han , Jinchao Li , Junan Li , Lingwei Meng , Xixin Wu , Helen Meng