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Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer's disease (AD), a growing global health challenge. To…

Foundation models have reshaped AI by unifying fragmented architectures into scalable backbones with multimodal reasoning and contextual adaptation. In parallel, the long-standing notion of AI agents, defined by the sensing-decision-action…

Machine Learning · Computer Science 2025-10-02 Sicong Liu , Weiye Wu , Xiangrui Xu , Teng Li , Bowen Pang , Bin Guo , Zhiwen Yu

Autonomous agents driven by Large Language Models (LLMs) offer enormous potential for automation. Early proof of this technology can be found in various demonstrations of agents solving complex tasks, interacting with external systems to…

Alzheimer's Disease (AD) is a prevalent neurodegenerative condition where early detection is vital. Handwriting, often affected early in AD, offers a non-invasive and cost-effective way to capture subtle motor changes. State-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Changqing Gong , Huafeng Qin , Mounîm A. El-Yacoubi

As generative AI (GenAI) agents become more common in enterprise settings, they introduce security challenges that differ significantly from those posed by traditional systems. These agents are not just LLMs; they reason, remember, and act,…

Cryptography and Security · Computer Science 2025-05-06 Vineeth Sai Narajala , Om Narayan

Dementia is a syndrome characterised by the decline of different cognitive abilities. Alzheimer's Disease (AD) is the most common dementia affecting cognitive domains such as memory and learning, perceptual-motion or executive function.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Juan Manuel Fernández Montenegro

Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-03 Utkarsh Sarawgi , Wazeer Zulfikar , Nouran Soliman , Pattie Maes

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia, affecting memory, reasoning, communication, and daily functioning. Early diagnosis is particularly important, as timely intervention may…

Sound · Computer Science 2026-05-26 Loukas Ilias , Dimitris Askounis

The concept of the 'agent' has profoundly shaped Artificial Intelligence (AI) research, guiding development from foundational theories to contemporary applications like Large Language Model (LLM)-based systems. This paper critically…

Artificial Intelligence · Computer Science 2025-09-16 Jesse Gardner , Vladimir A. Baulin

In an era where vast amounts of data are collected and processed from diverse sources, there is a growing demand for sophisticated AI systems capable of intelligently fusing and analyzing this information. To address these challenges,…

Software Engineering · Computer Science 2025-11-24 Amine Ben Hassouna , Hana Chaari , Ines Belhaj

Multi-agent systems (MAS) powered by large language models (LLMs) hold significant promise for solving complex decision-making tasks. However, the core process of collaborative decision-making (CDM) within these systems remains…

Artificial Intelligence · Computer Science 2025-08-19 Xuyang Zhao , Shiwan Zhao , Hualong Yu , Liting Zhang , Qicheng Li

The rapid advancement of Large Language Models (LLMs) has stimulated interest in multi-agent collaboration for addressing complex medical tasks. However, the practical advantages of multi-agent collaboration approaches remain insufficiently…

Artificial Intelligence · Computer Science 2025-10-31 Yinghao Zhu , Ziyi He , Haoran Hu , Xiaochen Zheng , Xichen Zhang , Zixiang Wang , Junyi Gao , Liantao Ma , Lequan Yu

While Multi-Agent Systems (MAS) show potential for complex clinical decision support, the field remains hindered by architectural fragmentation and the lack of standardized multimodal integration. Current medical MAS research suffers from…

Artificial Intelligence · Computer Science 2026-03-20 Yunhang Qian , Xiaobin Hu , Jiaquan Yu , Siyang Xin , Xiaokun Chen , Jiangning Zhang , Peng-Tao Jiang , Jiawei Liu , Hongwei Bran Li

This study explores a novel approach to advancing dementia care by integrating socially assistive robotics, reinforcement learning (RL), large language models (LLMs), and clinical domain expertise within a simulated environment. This…

Artificial Intelligence · Computer Science 2025-01-30 Fengpei Yuan , Nehal Hasnaeen , Ran Zhang , Bryce Bible , Joseph Riley Taylor , Hairong Qi , Fenghui Yao , Xiaopeng Zhao

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

Artificial Intelligence · Computer Science 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi

Building agents, systems that perceive and act upon their environment with a degree of autonomy, has long been a focus of AI research. This pursuit has recently become vastly more practical with the emergence of large language models (LLMs)…

Early and accurate diagnosis of Alzheimer's disease (AD) remains a critical challenge in neuroimaging-based clinical decision support systems. In this work, we propose a novel hybrid deep learning framework that integrates Topological Data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Faisal Ahmed

Large Language Models (LLMs) offer promising opportunities to support mental healthcare workflows, yet they often lack the structured clinical reasoning needed for reliable diagnosis and may struggle to provide the emotionally attuned…

Artificial Intelligence · Computer Science 2026-04-20 Yuqi Wu , Guangya Wan , Jingjing Li , Shengming Zhao , Lingfeng Ma , Tianyi Ye , Ion Pop , Yanbo Zhang , Jie Chen

While individual components of agentic architectures have been studied in isolation, there remains limited empirical understanding of how different design dimensions interact within complex multi-agent systems. This study aims to address…

Artificial Intelligence · Computer Science 2026-01-07 Tara Bogavelli , Roshnee Sharma , Hari Subramani

Modern disease classification often overlooks molecular commonalities hidden beneath divergent clinical presentations. This study introduces a transcriptomics-driven framework for discovering disease relationships by analyzing over 1300…

Genomics · Quantitative Biology 2025-08-08 Ke Chen , Haohan Wang
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