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Astronomical research traditionally relies on extensive domain knowledge to interpret observations and narrow down hypotheses. We demonstrate that this process can be emulated using large language model-based agents to accelerate research…

Instrumentation and Methods for Astrophysics · Physics 2025-08-05 Zechang Sun , Yuan-Sen Ting , Yaobo Liang , Nan Duan , Song Huang , Zheng Cai

Large Language Models (LLMs) are playing an increasingly important role in physics research by assisting with symbolic manipulation, numerical computation, and scientific reasoning. However, ensuring the reliability, transparency, and…

Artificial Intelligence · Computer Science 2025-08-19 Yinggan Xu , Hana Kimlee , Yijia Xiao , Di Luo

As spacecraft journey further from Earth with more complex missions, systems of greater autonomy and onboard intelligence are called for. Reducing reliance on human-based mission control becomes increasingly critical if we are to increase…

Robotics · Computer Science 2024-05-03 David Maranto

Agents based on large language models (LLMs) for machine learning engineering (MLE) can automatically implement ML models via code generation. However, existing approaches to build such agents often rely heavily on inherent LLM knowledge…

Machine Learning · Computer Science 2025-08-29 Jaehyun Nam , Jinsung Yoon , Jiefeng Chen , Jinwoo Shin , Sercan Ö. Arık , Tomas Pfister

Agentic systems built on large language models (LLMs) offer promising capabilities for automating complex workflows in healthcare AI. We introduce mAIstro, an open-source, autonomous multi-agentic framework for end-to-end development and…

Machine Learning · Computer Science 2025-10-15 Eleftherios Tzanis , Michail E. Klontzas

Computing has long served as a cornerstone of scientific discovery. Recently, a paradigm shift has emerged with the rise of large language models (LLMs), introducing autonomous systems, referred to as agents, that accelerate discovery…

We present MARVEL (https://ligogpt.mit.edu/marvel), a locally deployable, open-source framework for domain-aware question answering and assisted scientific research. It is designed to address the increasing demands of a digital assistant…

Instrumentation and Methods for Astrophysics · Physics 2026-01-08 Nikhil Mukund , Yifang Luo , Fan Zhang , Lisa Barsotti , Erik Katsavounidis

Large language models (LLMs) are catalyzing the development of autonomous AI research agents for scientific and engineering discovery. We present FM Agent, a novel and general-purpose multi-agent framework that leverages a synergistic…

The advent of next-generation radio telescopes is set to transform radio astronomy by producing massive data volumes that challenge traditional processing methods. Deep learning techniques have shown strong potential in automating radio…

Instrumentation and Methods for Astrophysics · Physics 2025-08-04 S. Riggi , T. Cecconello , A. Pilzer , S. Palazzo , N. Gupta , A. M. Hopkins , C. Trigilio , G. Umana

Large language models (LLMs) can label data faster and cheaper than humans for various NLP tasks. Despite their prowess, LLMs may fall short in understanding of complex, sociocultural, or domain-specific context, potentially leading to…

Computation and Language · Computer Science 2024-02-29 Hannah Kim , Kushan Mitra , Rafael Li Chen , Sajjadur Rahman , Dan Zhang

We show that multi-agent systems guided by vision-language models (VLMs) improve end-to-end autonomous scientific discovery. By treating plots as verifiable checkpoints, a VLM-as-a-judge evaluates figures against dynamically generated…

Computation and Language · Computer Science 2025-11-19 Kahaan Gandhi , Boris Bolliet , Inigo Zubeldia

Recent trends are emerging in the use of Large Language Models (LLMs) as autonomous agents that take actions based on the content of the user text prompts. We intend to apply these concepts to the field of Control in space, enabling LLMs to…

Artificial Intelligence · Computer Science 2025-07-16 Alejandro Carrasco , Victor Rodriguez-Fernandez , Richard Linares

We introduce an autonomous multiagent framework for mechanistic interpretability that automates both explaining and finding internal features in large language models. The system runs two coupled loops: (1) explanation refinement, where an…

Computation and Language · Computer Science 2026-05-05 Arnau Marin-Llobet , Javier Ferrando

Multi-agent systems (MAS) utilizing multiple Large Language Model agents with Retrieval Augmented Generation and that can execute code locally may become beneficial in cosmological data analysis. Here, we illustrate a first small step…

Instrumentation and Methods for Astrophysics · Physics 2024-12-04 Andrew Laverick , Kristen Surrao , Inigo Zubeldia , Boris Bolliet , Miles Cranmer , Antony Lewis , Blake Sherwin , Julien Lesgourgues

Large Language Model (LLM)-based agents have recently shown impressive capabilities in complex reasoning and tool use via multi-step interactions with their environments. While these agents have the potential to tackle complicated tasks,…

Artificial Intelligence · Computer Science 2025-11-04 Jiaye Lin , Yifu Guo , Yuzhen Han , Sen Hu , Ziyi Ni , Licheng Wang , Mingguang Chen , Hongzhang Liu , Ronghao Chen , Yangfan He , Daxin Jiang , Binxing Jiao , Chen Hu , Huacan Wang

To accelerate mechanical design and enhance design quality and innovation, we present a Multidisciplinary Design and Optimization (MDO) Agent driven by Large Language Models (LLMs). The agent semi-automates the end-to-end workflow by…

Human-Computer Interaction · Computer Science 2025-11-25 Bingkun Guo , Wentian Li , Xiaojian Liu , Jiaqi Luo , Zibin Yu , Dalong Dong , Shuyou Zhang , Yiming Zhang

This paper presents a learning-based guidance-and-control approach that couples a reasoning-enabled Large Language Model (LLM) with Group Relative Policy Optimization (GRPO). A two-stage procedure consisting of Supervised Fine-Tuning (SFT)…

Robotics · Computer Science 2026-01-09 Amit Jain , Richard Linares

Large Language Models (LLMs) are shifting how scientific research is done. It is imperative to understand how researchers interact with these models and how scientific sub-communities like astronomy might benefit from them. However, there…

The exponential growth of astronomical datasets provides an unprecedented opportunity for humans to gain insight into the Universe. However, effectively analyzing this vast amount of data poses a significant challenge. Astronomers are…

Instrumentation and Methods for Astrophysics · Physics 2024-05-20 Mingxiang Fu , Yu Song , Jiameng Lv , Liang Cao , Peng Jia , Nan Li , Xiangru Li , Jifeng Liu , A-Li Luo , Bo Qiu , Shiyin Shen , Liangping Tu , Lili Wang , Shoulin Wei , Haifeng Yang , Zhenping Yi , Zhiqiang Zou

Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction…

Artificial Intelligence · Computer Science 2026-03-04 Siqi Ma , Jiajie Huang , Fan Zhang , Yue Shen , Jinlin Wu , Guohui Fan , Zhu Zhang , Zelin Zang
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