English

Interpreting Multi-band Galaxy Observations with Large Language Model-Based Agents

Instrumentation and Methods for Astrophysics 2025-08-05 v2 Astrophysics of Galaxies

Abstract

Astronomical research traditionally relies on extensive domain knowledge to interpret observations and narrow down hypotheses. We demonstrate that this process can be emulated using large language model-based agents to accelerate research workflows. We propose mephisto, a multi-agent collaboration framework that mimics human reasoning to interpret multi-band galaxy observations. mephisto interacts with the CIGALE codebase, which includes spectral energy distribution (SED) models to explain observations. In this open-world setting, mephisto learns from its self-play experience, performs tree search, and accumulates knowledge in a dynamically updated base. As a proof of concept, we apply mephisto to the latest data from the James Webb Space Telescope. mephisto attains near-human proficiency in reasoning about galaxies' physical scenarios, even when dealing with a recently discovered population of "Little Red Dot" galaxies. This represents the first demonstration of agentic research in astronomy, advancing towards end-to-end research via LLM agents and potentially expediting astronomical discoveries.

Keywords

Cite

@article{arxiv.2409.14807,
  title  = {Interpreting Multi-band Galaxy Observations with Large Language Model-Based Agents},
  author = {Zechang Sun and Yuan-Sen Ting and Yaobo Liang and Nan Duan and Song Huang and Zheng Cai},
  journal= {arXiv preprint arXiv:2409.14807},
  year   = {2025}
}

Comments

Accepted at the NIPS ML4PS Workshop 2024. The journal version is in preparation. Code and data will be fully made public following the journal publication. We welcome any comments and feedback

R2 v1 2026-06-28T18:53:25.007Z