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Prediction of medical codes from clinical notes is both a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort spent by…

Computation and Language · Computer Science 2021-07-23 Byung-Hak Kim , Varun Ganapathi

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

In this study, we investigated the ability of the large language model (LLM) to enhance healthcare data interoperability. We leveraged the LLM to convert clinical texts into their corresponding FHIR resources. Our experiments, conducted on…

Computation and Language · Computer Science 2023-10-23 Yikuan Li , Hanyin Wang , Halid Yerebakan , Yoshihisa Shinagawa , Yuan Luo

Large language models (LLMs) are increasingly used to generate requirements specifications, design documents, code, and test cases. In contrast, much less attention has been given to a more difficult assurance problem: statically verifying…

Software Engineering · Computer Science 2026-05-19 Zhi Quan Zhou , Dave Towey , Tsong Yueh Chen

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

Artificial Intelligence · Computer Science 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Optimizing scientific software is a difficult task because codebases are often large and complex, and performance can depend upon several factors including the algorithm, its implementation, and hardware among others. Causes of poor…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-30 Daniel Nichols , Pranav Polasam , Harshitha Menon , Aniruddha Marathe , Todd Gamblin , Abhinav Bhatele

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Multimodal Large Language Models (MLLMs) have demonstrated remarkable potential in medical image analysis. However, their application in gastrointestinal endoscopy is currently hindered by two critical limitations: the misalignment between…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Huan Zheng , Yucheng Zhou , Tianyi Yan , Dubing Chen , Hongbo Lu , Wenlong Liao , Tao He , Pai Peng , Jianbing Shen

Legal multi-label classification is a critical task for organizing and accessing the vast amount of legal documentation. Despite its importance, it faces challenges such as the complexity of legal language, intricate label dependencies, and…

Computation and Language · Computer Science 2025-04-15 Emily Johnson , Xavier Holt , Noah Wilson

Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

Computation and Language · Computer Science 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti

Clinical text classification requires choosing between specialized fine-tuned models (BERT variants) and general-purpose large language models (LLMs), yet neither dominates across all instances. We introduce Learning to Defer for clinical…

Computation and Language · Computer Science 2026-04-16 Rishik Kondadadi , John E. Ortega

Clinical oncology generates vast, unstructured data that often contain inconsistencies, missing information, and ambiguities, making it difficult to extract reliable insights for data-driven decision-making. General-purpose large language…

Computation and Language · Computer Science 2025-03-12 Morteza Rohanian , Tarun Mehra , Nicola Miglino , Farhad Nooralahzadeh , Michael Krauthammer , Andreas Wicki

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Software testing and verification are critical for ensuring the reliability and security of modern software systems. Traditionally, formal verification techniques, such as model checking and theorem proving, have provided rigorous…

Software Engineering · Computer Science 2025-03-17 Norbert Tihanyi , Tamas Bisztray , Mohamed Amine Ferrag , Bilel Cherif , Richard A. Dubniczky , Ridhi Jain , Lucas C. Cordeiro

Building mathematical optimization models is critical in operations research (OR), while it requires substantial human expertise. Recent advancements have utilized large language models (LLMs) to automate this modeling process. However,…

Artificial Intelligence · Computer Science 2026-05-29 Haoyang Liu , Jie Wang , Boxuan Niu , Xiongwei Han , Yian Xu , Mingxuan Ye , Zijie Geng , Fangzhou Zhu , Tao Zhong , Mingxuan Yuan , Jianye Hao

Large Language Models (LLMs) are increasingly embedded in academic writing practices. Although numerous studies have explored how researchers employ these tools for scientific writing, their concrete implementation, limitations, and design…

Human-Computer Interaction · Computer Science 2025-12-15 Brenda Nogueira , Werner Geyer , Andrew Anderson , Toby Jia-Jun Li , Dongwhi Kim , Nuno Moniz , Nitesh V. Chawla

Medical report generation demands automatic creation of coherent and precise descriptions for medical images. However, the scarcity of labelled medical image-report pairs poses formidable challenges in developing large-scale neural networks…

Computer Vision and Pattern Recognition · Computer Science 2023-12-08 Shibin Wu , Bang Yang , Zhiyu Ye , Haoqian Wang , Hairong Zheng , Tong Zhang

Large language models (LLMs) are now rapidly advancing and surpassing human abilities on many natural language tasks. However, aligning these super-human LLMs with human knowledge remains challenging because the supervision signals from…

Computation and Language · Computer Science 2024-06-28 Yue Guo , Yi Yang

Conformance checking is a process mining technique that allows verifying the conformance of process instances to a given model. Thus, this technique is predestined to be used in the medical context for the comparison of treatment cases with…

Artificial Intelligence · Computer Science 2022-09-21 Joscha Grüger , Tobias Geyer , Martin Kuhn , Stefan Braun , Ralph Bergmann
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