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Nowadays, the screening methods for the early detection of lung cancer struggle with several limitations such as many false positive results and low sensitivity. The detection of specific biomarkers is of high interest to complement these…

Quantitative Methods · Quantitative Biology 2021-02-19 Juul Goossens , Jente Gieghase , Elien Derveaux , Peter Adriaensens

Lung cancer (LC) is a leading cause of cancer-related mortality in the United States. Accurate prediction of LC mortality rates is crucial for guiding targeted interventions and addressing health disparities. Although traditional…

Machine Learning · Computer Science 2025-12-23 Soheil Hashtarkhani , Brianna M. White , Benyamin Hoseini , David L. Schwartz , Arash Shaban-Nejad

With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer death in the United States. Lung cancer CT screening has been shown to reduce mortality by up to 40% and is now included in US screening guidelines.…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Daniel Korat

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, with lung metastases being the most common site of distant spread and significantly worsening prognosis. Despite the growing availability of clinical and…

Tissues and Organs · Quantitative Biology 2025-01-22 Jeff J. H. Kim , George R. Nahass , Yang Dai , Theja Tulabandhula

Lung cancer remains a leading cause of cancer-related deaths globally, with non-small cell lung cancer (NSCLC) being the most common subtype. This study aimed to identify key biomarkers associated with stage III NSCLC in non-smoking females…

Genomics · Quantitative Biology 2024-09-02 Huili Zheng , Qimin Zhang , Yiru Gong , Zheyan Liu , Shaohan Chen

Until the beginning of 2021, lung cancer is known to be the most common cancer in the world. The disease is common due to factors such as occupational exposure, smoking and environmental pollution. The early diagnosis and treatment of the…

Machine Learning · Computer Science 2021-05-21 Asim Leblebici , Omer Gesoglu , Yasemin Basbinar

Lung cancer is the leading cause of cancer death worldwide. The critical reason for the deaths is delayed diagnosis and poor prognosis. With the accelerated development of deep learning techniques, it has been successfully applied…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yujiao Wu , Jie Ma , Xiaoshui Huang , Sai Ho Ling , Steven Weidong Su

Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most prevalent form of lung cancer. EGFR positive lung adenocarcinomas have been shown to have high response rates to TKI therapy, underlying the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Gabriele Campanella , David Ho , Ida Häggström , Anton S Becker , Jason Chang , Chad Vanderbilt , Thomas J Fuchs

Lung cancer is a leading cause of death worldwide. Early-stage detection of lung cancer is essential for a more favorable prognosis. Radiogenomics is an emerging discipline that combines medical imaging and genomics features for modeling…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Ivo Gollini Navarrete , Mohammad Yaqub

According to GHO (Global Health Observatory (GHO), the high prevalence of a large variety of diseases such as Ischaemic heart disease, stroke, lung cancer disease and lower respiratory infections have remained the top killers during the…

Artificial Intelligence · Computer Science 2020-09-17 Mayssa Ben Kahla , Dalel Kanzari , Ahmed Maalel

Lung cancer is among the most common cancers in the United States, in terms of incidence and mortality. In 2009, it is estimated that more than 150,000 deaths will result from lung cancer alone. Genetic information is an extremely valuable…

Applications · Statistics 2011-08-10 Brent A. Johnson , Qi Long

Lung cancer is a significant cause of mortality worldwide, emphasizing the importance of early detection for improved survival rates. In this study, we propose a machine learning (ML) tool trained on data from the PLCO Cancer Screening…

Machine Learning · Computer Science 2023-08-24 Pierre-Louis Benveniste , Julie Alberge , Lei Xing , Jean-Emmanuel Bibault

Early detection of lung cancer is critical for improvement of patient survival. To address the clinical need for efficacious treatments, genetically engineered mouse models (GEMM) have become integral in identifying and evaluating the…

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

Lung cancer, a leading cause of cancer-related deaths globally, emphasises the importance of early detection for better patient outcomes. Pulmonary nodules, often early indicators of lung cancer, necessitate accurate, timely diagnosis.…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Jiahao Lu , Chong Yin , Silvia Ingala , Kenny Erleben , Michael Bachmann Nielsen , Sune Darkner

Cancer is a term that denotes a group of diseases caused by abnormal growth of cells that can spread in different parts of the body. According to the World Health Organization (WHO), cancer is the second major cause of death after…

Machine Learning · Computer Science 2023-01-31 Fadi Alharbi , Aleksandar Vakanski

Lung cancer (LC) remains the primary cause of cancer-related mortality, largely due to late-stage diagnoses. Effective strategies for early detection are therefore of paramount importance. In recent years, machine learning (ML) has…

Lung cancer, the second leading cause of cancer-related deaths, is primarily linked to long-term tobacco smoking (85% of cases). Surprisingly, 10-15% of cases occur in non-smokers. In 2020, approximately 2 million people were affected…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Imama Ajmi , Abhishek Das

Lung cancer is a condition where there is abnormal growth of malignant cells that spread in an uncontrollable fashion in the lungs. Some common treatment strategies are surgery, chemotherapy, and radiation which aren't the best options due…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Ann Rachel , Pranav M Pawar , Mithun Mukharjee , Raja M , Tojo Mathew

Lung cancer is the leading cause of the largest number of deaths worldwide and lung adenocarcinoma (LUAD) is the most common form of lung cancer. In this study, we carried out an integrated meta-analysis of the mutations including…

Genomics · Quantitative Biology 2020-10-02 Talip Zengin , Tuğba Önal-Süzek
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