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Understanding cellular trajectories via time-resolved single-cell transcriptomics is vital for studying development, regeneration, and disease. A key challenge is inferring continuous trajectories from discrete snapshots. Biological…

Across the Artificial Intelligence (AI) lifecycle - from hardware to development, deployment, and reuse - burdens span energy, carbon, water, and embodied impacts. Cloud provider tools improve transparency but remain heterogeneous and often…

Artificial Intelligence · Computer Science 2025-11-14 Marcel Rojahn , Marcus Grum

Artificial intelligence (AI) has been widely used in bioimage image analysis nowadays, but the efficiency of AI models, like the energy consumption and latency is not ignorable due to the growing model size and complexity, as well as the…

Machine Learning · Computer Science 2023-06-14 Yu Zhou , Justin Sonneck , Sweta Banerjee , Stefanie Dörr , Anika Grüneboom , Kristina Lorenz , Jianxu Chen

Machine learning in medical imaging during clinical routine is impaired by changes in scanner protocols, hardware, or policies resulting in a heterogeneous set of acquisition settings. When training a deep learning model on an initial…

Computer Vision and Pattern Recognition · Computer Science 2022-03-16 Matthias Perkonigg , Johannes Hofmanninger , Christian Herold , Helmut Prosch , Georg Langs

Supervised machine learning classifiers sometimes face challenges related to the performance, accuracy, or overfitting. This paper introduces the Artificial Liver Classifier (ALC), a novel supervised learning model inspired by the human…

Artificial Intelligence · Computer Science 2025-09-24 Mahmood A. Jumaah , Yossra H. Ali , Tarik A. Rashid

Very High Resolution satellite and aerial imagery are used to monitor and conduct large scale surveys of ecological systems. Convolutional Neural Networks have successfully been employed to analyze such imagery to detect large animals and…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-10-29 Aymen Al-Saadi , Ioannis Paraskevakos , Bento Collares Gonçalves , Heather J. Lynch , Shantenu Jha , Matteo Turilli

AI integration is revolutionizing the landscape of HPC simulations, enhancing the importance, use, and performance of AI-driven HPC workflows. This paper surveys the diverse and rapidly evolving field of AI-driven HPC and provides a common…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-26 Wes Brewer , Ana Gainaru , Frédéric Suter , Feiyi Wang , Murali Emani , Shantenu Jha

Quantitative characterization of cellular spatial organization is critical for understanding tumor progression and immune response. Recent advances in artificial intelligence (AI) enable large-scale segmentation and classification of nuclei…

Single-cell RNA sequencing (scRNA-seq) technology enables systematic delineation of cellular states and interactions, providing crucial insights into cellular heterogeneity. Building on this potential, numerous computational methods have…

Genomics · Quantitative Biology 2025-11-11 Ping Xu , Zaitian Wang , Zhirui Wang , Pengjiang Li , Ran Zhang , Gaoyang Li , Hanyu Xie , Jiajia Wang , Yuanchun Zhou , Pengfei Wang

The modern deep learning field is a scale-centric one. Larger models have been shown to consistently perform better than smaller models of similar architecture. In many sub-domains of biomedical research, however, the model scaling is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Nicholas Kuang , Vanessa Scalon , Ji Yu

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

A growing trend in modern data analysis is the integration of data management with learning, guided by accuracy, latency, and cost requirements. In practice, applications draw data of different formats from many sources. In the meanwhile,…

Databases · Computer Science 2025-10-15 Meihui Zhang , Liming Wang , Chi Zhang , Zhaojing Luo

Despite their superior performance, deep-learning methods often suffer from the disadvantage of needing large-scale well-annotated training data. In response, recent literature has seen a proliferation of efforts aimed at reducing the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Ji Yu

Model parameter inference is a universal problem across science. This challenge is particularly pronounced in developmental biology, where faithful mechanistic descriptions require spatial-stochastic models with numerous parameters, yet…

Biological Physics · Physics 2024-07-16 Michael A. Ramirez-Sierra , Thomas R. Sokolowski

Imaging in clinical routine is subject to changing scanner protocols, hardware, or policies in a typically heterogeneous set of acquisition hardware. Accuracy and reliability of deep learning models suffer from those changes as data and…

Machine Learning · Computer Science 2021-06-08 Matthias Perkonigg , Johannes Hofmanninger , Georg Langs

Optical tomography has emerged as a non-invasive imaging method, providing three-dimensional insights into subcellular structures and thereby enabling a deeper understanding of cellular functions, interactions, and processes. Conventional…

Medical Physics · Physics 2023-12-14 Jiawei Sun , Bin Yang , Nektarios Koukourakis , Jochen Guck , Juergen W. Czarske

While Whole Slide Imaging (WSI) scanners remain the gold standard for digitizing pathology samples, their high cost limits accessibility in many healthcare settings. Other low-cost solutions also face critical limitations: automated…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Yousef Yeganeh , Maximilian Frantzen , Michael Lee , Kun-Hsing Yu , Nassir Navab , Azade Farshad

We introduce LAESI, a Synthetic Leaf Dataset of 100,000 synthetic leaf images on millimeter paper, each with semantic masks and surface area labels. This dataset provides a resource for leaf morphology analysis primarily aimed at beech and…

Saliency detection, finding the most important parts of an image, has become increasingly popular in computer vision. In this paper, we introduce Hierarchical Cellular Automata (HCA) -- a temporally evolving model to intelligently detect…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Yao Qin , Mengyang Feng , Huchuan Lu , Garrison W. Cottrell
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