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The rapid advancement of AI and computer vision has significantly increased the demand for high-quality annotated datasets, particularly for semantic segmentation. However, creating such datasets is resource-intensive, requiring substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ngoc-Do Tran , Minh-Tuan Huynh , Tam V. Nguyen , Minh-Triet Tran , Trung-Nghia Le

Proteins are sequences of amino acids that serve as the basic building blocks of living organisms. Despite rapidly growing databases documenting structural and functional information for various protein sequences, our understanding of…

Biomolecules · Quantitative Biology 2025-01-06 Weihang Dai

Mathematical formulas serve as the means of communication between humans and nature, encapsulating the operational laws governing natural phenomena. The concise formulation of these laws is a crucial objective in scientific research and an…

Machine Learning · Computer Science 2024-12-20 Yanjie Li , Weijun Li , Lina Yu , Min Wu , Jinyi Liu , Wenqiang Li , Meilan Hao , Shu Wei , Yusong Deng

We introduce an end-to-end computational framework that allows for hyperparameter optimization using the DeepHyper library, accelerated model training, and interpretable AI inference. The framework is based on state-of-the-art AI models…

Materials Science · Physics 2023-08-16 Hyun Park , Ruijie Zhu , E. A. Huerta , Santanu Chaudhuri , Emad Tajkhorshid , Donny Cooper

Artificial intelligence (AI) is increasingly being utilized to optimize magnetic resonance imaging (MRI) protocols. Given that image details are critical for diagnostic accuracy, optimizing MRI acquisition protocols is essential for…

Machine Learning · Computer Science 2025-02-05 Alice Vian , Diego Andre Eifer , Mauricio Anes , Guilherme Ribeiro Garcia , Mariana Recamonde-Mendoza

Artificial intelligence (AI) provides many opportunities to improve private and public life. Discovering patterns and structures in large troves of data in an automated manner is a core component of data science, and currently drives…

Machine Learning · Computer Science 2020-09-25 Vaishak Belle , Ioannis Papantonis

As deep neural networks are growing in size and being increasingly deployed to more resource-limited devices, there has been a recent surge of interest in network pruning methods, which aim to remove less important weights or activations of…

Machine Learning · Computer Science 2020-06-23 Minyoung Song , Jaehong Yoon , Eunho Yang , Sung Ju Hwang

The rise in loosely-structured data available through text, images, and other modalities has called for new ways of querying them. Multimedia Information Retrieval has filled this gap and has witnessed exciting progress in recent years.…

Multimedia · Computer Science 2024-01-31 Giovanni Trappolini , Andrea Santilli , Emanuele Rodolà , Alon Halevy , Fabrizio Silvestri

Proteins and other macromolecules exist not in a single state but as dynamic ensembles of interconverting conformations, which are essential for catalysis, allosteric regulation, and molecular recognition. While AI-based structure…

Biomolecules · Quantitative Biology 2025-10-22 Stephanie A. Wankowicz , Massimiliano Bonomi

Large Language Models (LLMs) have demonstrated remarkable capabilities on general text; however, their proficiency in specialized scientific domains that require deep, interconnected knowledge remains largely uncharacterized. Metabolomics…

Computation and Language · Computer Science 2025-10-17 Yuxing Lu , Xukai Zhao , J. Ben Tamo , Micky C. Nnamdi , Rui Peng , Shuang Zeng , Xingyu Hu , Jinzhuo Wang , May D. Wang

Unlike human-engineered systems such as aeroplanes, where each component's role and dependencies are well understood, the inner workings of AI models remain largely opaque, hindering verifiability and undermining trust. This paper…

This study investigates the automation of meta-analysis in scientific documents using large language models (LLMs). Meta-analysis is a robust statistical method that synthesizes the findings of multiple studies support articles to provide a…

Computation and Language · Computer Science 2024-11-19 Jawad Ibn Ahad , Rafeed Mohammad Sultan , Abraham Kaikobad , Fuad Rahman , Mohammad Ruhul Amin , Nabeel Mohammed , Shafin Rahman

The breakthrough in Deep Learning neural networks has transformed the use of AI and machine learning technologies for the analysis of very large experimental datasets. These datasets are typically generated by large-scale experimental…

Machine Learning · Computer Science 2021-10-26 Jeyan Thiyagalingam , Mallikarjun Shankar , Geoffrey Fox , Tony Hey

The rapid proliferation of artificial intelligence (AI) models and methods presents growing challenges for research software engineers and researchers who must select, integrate, and maintain appropriate models within complex research…

While many good textbooks are available on Protein Structure, Molecular Simulations, Thermodynamics and Bioinformatics methods in general, there is no good introductory level book for the field of Structural Bioinformatics. This book aims…

Augmented generation techniques such as Retrieval-Augmented Generation (RAG) and Cache-Augmented Generation (CAG) have revolutionized the field by enhancing large language model (LLM) outputs with external knowledge and cached information.…

Software Engineering · Computer Science 2024-02-23 Guanyu Wang , Yuekang Li , Yi Liu , Gelei Deng , Tianlin Li , Guosheng Xu , Yang Liu , Haoyu Wang , Kailong Wang

Interpolation-based Data Augmentation (DA) methods (Mixup) linearly interpolate the inputs and labels of two or more training examples. Mixup has more recently been adapted to the field of Natural Language Processing (NLP), mainly for…

Computation and Language · Computer Science 2023-11-17 Yuxin Pei , Pushkar Bhuse , Zhengzhong Liu , Eric Xing

The limits of molecular dynamics (MD) simulations of macromolecules are steadily pushed forward by the relentless developments of computer architectures and algorithms. This explosion in the number and extent (in size and time) of MD…

In recent years, the integration of Machine Learning (ML) models with Operation Research (OR) tools has gained popularity across diverse applications, including cancer treatment, algorithmic configuration, and chemical process optimization.…

Machine Learning · Computer Science 2023-07-17 Matteo Cacciola , Antonio Frangioni , Andrea Lodi

High stakes decision-making often requires a continuous interplay between evolving evidence and shifting hypotheses, a dynamic that is not well supported by current AI decision support systems. In this paper, we introduce a mixed-initiative…

Human-Computer Interaction · Computer Science 2025-04-23 Chengbo Zheng , Tim Miller , Alina Bialkowski , H Peter Soyer , Monika Janda
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