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Paralinguistic properties of speech are essential in analyzing and choosing optimal treatment options for patients with speech disorders. However, automatic modeling of these characteristics is difficult due to the lack of labeled speech…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-25 Jenthe Thienpondt , Geoffroy Vanderreydt , Abdessalem Hammami , Kris Demuynck

Parkinson's Disease (PD) is a progressive nervous system disorder that has affected more than 5.8 million people, especially the elderly. Due to the complexity of its symptoms and its similarity to other neurological disorders, early…

Artificial Intelligence · Computer Science 2022-11-29 Jingwei Li , Ruitian Wu , Tzu-liang Huang , Zian Pan , Ming-chun Huang

Parkinson's disease (PD) has been found to affect 1 out of every 1000 people, being more inclined towards the population above 60 years. Leveraging wearable-systems to find accurate biomarkers for diagnosis has become the need of the hour,…

Machine Learning · Computer Science 2023-04-20 Poojaa C , John Sahaya Rani Alex

Aphasia is a language disorder that affects the speaking ability of millions of patients. This paper presents a new benchmark for Aphasia speech recognition and detection tasks using state-of-the-art speech recognition techniques with the…

Audio and Speech Processing · Electrical Eng. & Systems 2023-05-24 Jiyang Tang , William Chen , Xuankai Chang , Shinji Watanabe , Brian MacWhinney

Parkinson's disease (PD) is a common neurodegenerative disorder that severely diminishes patients' quality of life. Its global prevalence has increased markedly in recent decades. Current diagnostic workflows are complex and heavily reliant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Shuai Shao , Yan Wang , Shu Jiang , Shiyuan Zhao , Di Yang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…

Sound · Computer Science 2025-11-20 Abishek Karthik , Pandiyaraju V , Dominic Savio M , Rohit Swaminathan S

Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam

Automatic detection and severity assessment of dysarthria are crucial for delivering targeted therapeutic interventions to patients. While most existing research focuses primarily on speech modality, this study introduces a novel approach…

Artificial Intelligence · Computer Science 2025-04-29 Anuprabha M , Krishna Gurugubelli , V Kesavaraj , Anil Kumar Vuppala

Imprecise vowel articulation can be observed in people with Parkinson's disease (PD). Acoustic features measuring vowel articulation have been demonstrated to be effective indicators of PD in its assessment. Standard clinical vowel…

Audio and Speech Processing · Electrical Eng. & Systems 2021-08-18 Yuanyuan Liu , Nelly Penttilä , Tiina Ihalainen , Juulia Lintula , Rachel Convey , Okko Räsänen

Diagnosing autism spectrum disorder (ASD) by identifying abnormal speech patterns from examiner-patient dialogues presents significant challenges due to the subtle and diverse manifestations of speech-related symptoms in affected…

Sound · Computer Science 2024-05-09 Chuanbo Hu , Jacob Thrasher , Wenqi Li , Mindi Ruan , Xiangxu Yu , Lynn K Paul , Shuo Wang , Xin Li

As the number of automatic tools based on machine learning (ML) and resting-state electroencephalography (rs-EEG) for Parkinson's disease (PD) detection keeps growing, the assessment of possible exacerbation of health disparities by means…

Signal Processing · Electrical Eng. & Systems 2023-03-14 Anna Kurbatskaya , Alberto Jaramillo-Jimenez , John Fredy Ochoa-Gomez , Kolbjørn Brønnick , Alvaro Fernandez-Quilez

Goal: Numerous studies had successfully differentiated normal and abnormal voice samples. Nevertheless, further classification had rarely been attempted. This study proposes a novel approach, using continuous Mandarin speech instead of a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-23 Syu-Siang Wang , Chi-Te Wang , Chih-Chung Lai , Yu Tsao , Shih-Hau Fang

In this paper, we combined linguistic complexity and (dis)fluency features with pretrained language models for the task of Alzheimer's disease detection of the 2021 ADReSSo (Alzheimer's Dementia Recognition through Spontaneous Speech)…

Computation and Language · Computer Science 2021-06-17 Yu Qiao , Xuefeng Yin , Daniel Wiechmann , Elma Kerz

Background: Captured between clinical appointments using mobile devices, spoken language has potential for objective, more regular assessment of symptom severity and earlier detection of relapse in major depressive disorder. However,…

We investigate the potential association between leucine-rich repeat kinase 2 (LRRK2) mutations and voice. Sustained phonations ('aaah' sounds) were recorded from 7 individuals with LRRK2-associated Parkinson's disease (PD), 17 participants…

Chronic Obstructive Pulmonary Disease (COPD) is a serious and debilitating disease affecting millions around the world. Its early detection using non-invasive means could enable preventive interventions that improve quality of life and…

Naturalistic speech recordings usually contain speech signals from multiple speakers. This phenomenon can degrade the performance of speech technologies due to the complexity of tracing and recognizing individual speakers. In this study, we…

Audio and Speech Processing · Electrical Eng. & Systems 2020-02-14 Midia Yousefi , John H. L. Hansen

Parkinson's Disease PD is a progressive neurodegenerative disorder that affects motor and cognitive functions with early diagnosis being critical for effective clinical intervention Electroencephalography EEG offers a noninvasive and…

Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing…

Neurons and Cognition · Quantitative Biology 2026-04-01 Siyuan Du , Siyi Li , Shuwei Bai , Ang Li , Haolin Li , Mingqing Xiao , Yang Pan , Dongsheng Li , Weidi Xie , Yanfeng Wang , Ya Zhang , Chencheng Zhang , Jiangchao Yao

Parkinson's disease (PD) is debilitating, progressive, and clinically marked by motor symptoms. As the second most common neurodegenerative disease in the world, it affects over 10 million lives globally. Existing diagnoses methods have…

Machine Learning · Computer Science 2021-11-30 Riya Tyagi , Tanish Tyagi , Ming Wang , Lujin Zhang