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We propose a Perceiver-based sequence classifier to detect abnormalities in speech reflective of several neurological disorders. We combine this classifier with a Universal Speech Model (USM) that is trained (unsupervised) on 12 million…

Audio and Speech Processing · Electrical Eng. & Systems 2023-10-23 Hagen Soltau , Izhak Shafran , Alex Ottenwess , Joseph R. JR Duffy , Rene L. Utianski , Leland R. Barnard , John L. Stricker , Daniela Wiepert , David T. Jones , Hugo Botha

Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

Neurons and Cognition · Quantitative Biology 2025-09-18 Aaron Herrera , Hina Shaheen

Speech intelligibility can be affected by multiple factors, such as noisy environments, channel distortions or physiological issues. In this work, we deal with the problem of automatic prediction of the speech intelligibility level in this…

Audio and Speech Processing · Electrical Eng. & Systems 2024-02-06 Ascensión Gallardo-Antolín , Juan M. Montero

Electroencephalography has been established as an effective method for detecting Parkinson's disease, typically diagnosed early.Current Parkinson's disease detection methods have shown significant success within individual datasets,…

Machine Learning · Computer Science 2025-08-21 Qian Zhang , Ruilin Zhang , Biaokai Zhu , Xun Han , Jun Xiao , Yifan Liu , Zhe Wang

Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Mengyu Li , Ingibjörg Kristjánsdóttir , Thilo van Eimeren , Kathrin Giehl , Lotta M. Ellingsen , the ASAP Neuroimaging Initiative

Despite rapid advancement in recent years, current speech enhancement models often produce speech that differs in perceptual quality from real clean speech. We propose a learning objective that formalizes differences in perceptual quality,…

Parkinson's disease (PD) is one of the most common neurodegenerative disorder. PD telemonitoring emerges as a novel assessment modality enabling self-administered at-home tests of Unified Parkinson's Disease Rating Scale (UPDRS) scores,…

Machine Learning · Computer Science 2025-10-03 Ziming Tang , Chengbin Hou , Tianyu Zhang , Bangxu Tian , Jinbao Wang , Hairong Lv

Hypernasality is a common characteristic symptom across many motor-speech disorders. For voiced sounds, hypernasality introduces an additional resonance in the lower frequencies and, for unvoiced sounds, there is reduced articulatory…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-14 Michael Saxon , Ayush Tripathi , Yishan Jiao , Julie Liss , Visar Berisha

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

Objective: The aim of this study is to develop a smartphone-based high-frequency remote monitoring platform, assess its feasibility for remote monitoring of symptoms in Parkinson's disease, and demonstrate the value of data collected using…

Computers and Society · Computer Science 2016-01-06 Andong Zhan , Max A. Little , Denzil A. Harris , Solomon O. Abiola , E. Ray Dorsey , Suchi Saria , Andreas Terzis

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

Machine Learning · Computer Science 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

Aphasia is a common speech and language disorder, typically caused by a brain injury or a stroke, that affects millions of people worldwide. Detecting and assessing Aphasia in patients is a difficult, time-consuming process, and numerous…

Automatic detection of Parkinson's disease (PD) from speech is a promising non-invasive diagnostic tool, but it raises significant privacy concerns. Speaker anonymization mitigates these risks, but it may suppress the pathological…

Sound · Computer Science 2026-03-10 Carlos Franzreb , Francisco Teixeira , Ben Luks , Sebastian Möller , Alberto Abad

The potential of speech as a non-invasive biomarker to assess a speaker's health has been repeatedly supported by the results of multiple works, for both physical and psychological conditions. Traditional systems for speech-based disease…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-02 Catarina Botelho , Francisco Teixeira , Thomas Rolland , Alberto Abad , Isabel Trancoso

Overlapping Speech Detection (OSD) aims to identify regions where multiple speakers overlap in a conversation, a critical challenge in multi-party speech processing. This work proposes a speaker-aware progressive OSD model that leverages a…

Sound · Computer Science 2025-05-30 Zhaokai Sun , Li Zhang , Qing Wang , Pan Zhou , Lei Xie

Stuttering affects approximately 1% of the global population, impacting communication and quality of life. While recent advances in deep learning have pushed the boundaries of automatic speech dysfluency detection, rule-based approaches…

Artificial Intelligence · Computer Science 2025-08-26 Eric Zhang

Parkinson's disease (PD), a prevalent neurodegenerative disorder, significantly affects patients' daily functioning and social interactions. To facilitate a more efficient and accessible diagnostic approach for PD, we propose a dynamic…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Xiaochen Huang , Xiaochen Bi , Cuihua Lv , Xin Wang , Haoyan Zhang , Wenjing Jiang , Xin Ma , Yibin Li

Clinical diagnosis of stuttering requires an assessment by a licensed speech-language pathologist. However, this process is time-consuming and requires clinicians with training and experience in stuttering and fluency disorders.…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-18 Yi-Jen Shih , Zoi Gkalitsiou , Alexandros G. Dimakis , David Harwath

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Machine Learning · Computer Science 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

Parkinson's Disease (PD) is a slowly evolving neuro-logical disease that affects about 1% of the population above 60 years old, causing symptoms that are subtle at first, but whose intensity increases as the disease progresses. Automated…

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