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Cellular membranes exhibit a large variety of shapes, strongly coupled to their function. Many biological processes involve dynamic reshaping of membranes, usually mediated by proteins. This interaction works both ways: while proteins…

Soft Condensed Matter · Physics 2018-06-12 Afshin Vahid , Anđela Šarić , Timon Idema

Mechanochemical processes on surfaces such as the cellular cortex or epithelial sheets, play a key role in determining patterns and shape changes of biological systems. To understand the complex interplay of hydrodynamics and material flows…

Soft Condensed Matter · Physics 2023-05-04 Lucas D. Wittwer , Sebastian Aland

We present a theory that combines the framework of irreversible thermodynamics with modified integral theorems to model arbitrarily curved and deforming membranes immersed in bulk fluid solutions. We study the coupling between the mechanics…

Soft Condensed Matter · Physics 2025-09-29 Ahmad M. Alkadri , Kranthi K. Mandadapu

Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

Soft Condensed Matter · Physics 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

The shape dynamics of fluid vesicles is governed by the coupling of the flow within the two-dimensional membrane to the hydrodynamics of the surrounding bulk fluid. We present a numerical scheme which is capable of solving this flow problem…

Condensed Matter · Physics 2009-10-28 Martin Kraus , Wolfgang Wintz , Udo Seifert , Reinhard Lipowsky

We study the kinematics and dynamics of a highly compliant membrane disk placed head-on in a uniform flow. With increasing flow velocity, the membrane deforms nonlinearly into increasingly parachute-like shapes. These aerodynamically…

Fluid Dynamics · Physics 2023-09-11 Varghese Mathai , Asimanshu Das , Dante L. Naylor , Kenneth S. Breuer

Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg

A phase field model for dealing with shape instabilities in fluid membrane vesicles is presented. This model takes into account the Canham-Helfrich bending energy with spontaneous curvature. A dynamic equation for the phase-field is also…

Soft Condensed Matter · Physics 2007-07-26 F. Campelo , A. Hernandez-Machado

Within a coupled-field Ginzburg-Landau model we study analytically phase separation and accompanying shape deformation on a two-phase elastic membrane in simple geometries such as cylinders, spheres and tori. Using an exact periodic domain…

Soft Condensed Matter · Physics 2009-10-31 Y. Jiang , T. Lookman , A. Saxena

Mode mixing in optical fibers caused by mechanical bending induces perturbations that distort the spatial field profile of coherent beams as they propagate through few-mode or multimode fibers. The observed output from a bent fiber commonly…

In this work, the nonlinear dynamics of a fully three-dimensional multicomponent vesicle in shear flow are explored. Using a volume- and area-conserving projection method coupled to a gradient-augmented level set and surface phase method,…

Soft Condensed Matter · Physics 2018-05-22 Prerna Gera , David Salac

Motivated by a long-standing debate concerning the nature and interrelations of surface-tension variables in fluid membranes, we reformulate the thermodynamics of a membrane vesicle as a generic two-dimensional finite system enclosing a…

Soft Condensed Matter · Physics 2012-02-03 Haim Diamant

In this work, we present a mathematical and computational framework to model the dynamics of open lipid bilayer membranes interacting with ambient Stokes flow. The model explicitly couples the three-dimensional viscous fluid, the…

Numerical Analysis · Mathematics 2026-01-21 Han Zhou , Yuan-Nan Young , Yoichiro Mori

The biological membrane, which compartmentalizes the cell and its organelles, exhibit wide variety of macroscopic shapes of varying morphology and topology. A systematic understanding of the relation of membrane shapes to composition,…

Biological Physics · Physics 2011-09-23 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

Within the framework of variational modelling we derive a one-phase moving boundary problem describing the motion of a semipermeable membrane enclosing a viscous liquid, driven by osmotic pressure and surface tension of the membrane. For…

Analysis of PDEs · Mathematics 2019-02-20 Friedrich Lippoth , Mark A. Peletier , Georg Prokert

We study large deformations of hyperelastic membranes using a purely two-dimensional formulation derived from basic balance principles within a modern geometric setting, ensuring a framework that is independent of an underlying…

Soft Condensed Matter · Physics 2025-09-22 Claudia Grabs , Werner Wirges

We present a novel Monte Carlo simulation of the phase separation dynamics of a model fluid membrane. Such a phase segregation induces shape changes of the membrane and results in local `budding' under favourable conditions. We present a…

Condensed Matter · Physics 2007-05-23 P. B. Sunil Kumar , Madan Rao

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd

In the study of equilibrium solutions for partial differential equations there are so many equilibria that one cannot hope to find them all. Therefore one usually concentrates on finding individual branches of equilibrium solutions. On the…

Dynamical Systems · Mathematics 2021-10-06 Evelyn Sander , Thomas Wanner

In this paper, we study a hydrodynamic system modeling the deformation of vesicle membranes in incompressible viscous fluids. The system consists of the Navier-Stokes equations coupled with a fourth order phase-field equation. In the three…

Analysis of PDEs · Mathematics 2013-02-26 Hao Wu , Xiang Xu