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Recent Multimodal Large Language Models (MLLMs) have demonstrated significant progress in perceiving and reasoning over multimodal inquiries, ushering in a new research era for foundation models. However, vision-language misalignment in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Wei-Yao Wang , Zhao Wang , Helen Suzuki , Yoshiyuki Kobayashi

Large Language Models (LLMs) are capable of performing zero-shot closed-book question answering tasks, based on their internal knowledge stored in parameters during pre-training. However, such internalized knowledge might be insufficient…

Computation and Language · Computer Science 2023-06-08 Jinheon Baek , Alham Fikri Aji , Amir Saffari

Large Language Models (LLMs) have emerged as powerful tools for accelerating scientific discovery, yet their static knowledge and hallucination issues hinder autonomous research applications. Recent advances integrate LLMs into agentic…

Artificial Intelligence · Computer Science 2025-12-23 Zeyu Xia , Jinzhe Ma , Congjie Zheng , Shufei Zhang , Yuqiang Li , Hang Su , P. Hu , Changshui Zhang , Xingao Gong , Wanli Ouyang , Lei Bai , Dongzhan Zhou , Mao Su

Large Language Model (LLM) agent systems have advanced rapidly, driven by their strong generalization in zero-shot settings. To further enhance reasoning and accuracy on complex tasks, Multi-Agent Debate (MAD) has emerged as a promising…

Computation and Language · Computer Science 2025-12-03 Wei Fan , JinYi Yoon , Bo Ji

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

We introduce MedXpertQA, a highly challenging and comprehensive benchmark to evaluate expert-level medical knowledge and advanced reasoning. MedXpertQA includes 4,460 questions spanning 17 specialties and 11 body systems. It includes two…

Artificial Intelligence · Computer Science 2025-06-09 Yuxin Zuo , Shang Qu , Yifei Li , Zhangren Chen , Xuekai Zhu , Ermo Hua , Kaiyan Zhang , Ning Ding , Bowen Zhou

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Medical reasoning models remain constrained by parametric knowledge and are thus susceptible to forgetting and hallucinations. DeepResearch (DR) models ground outputs in verifiable evidence from tools and perform strongly in general…

Artificial Intelligence · Computer Science 2026-02-05 Zihan Wang , Hao Wang , Shi Feng , Xiaocui Yang , Daling Wang , Yiqun Zhang , Jinghao Lin , Haihua Yang , Xiaozhong Ji

The rise of multimodal misinformation on social platforms poses significant challenges for individuals and societies. Its increased credibility and broader impact compared to textual misinformation make detection complex, requiring robust…

Computation and Language · Computer Science 2024-06-24 Keyang Xuan , Li Yi , Fan Yang , Ruochen Wu , Yi R. Fung , Heng Ji

Vision-language foundation models (VLMs) have shown great potential in feature transfer and generalization across a wide spectrum of medical-related downstream tasks. However, fine-tuning these models is resource-intensive due to their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ye Du , Nanxi Yu , Shujun Wang

Alzheimer's Disease Analysis Model (ADAM) is a multi-agent reasoning large language model (LLM) framework designed to integrate and analyze multimodal data, including microbiome profiles, clinical datasets, and external knowledge bases, to…

Artificial Intelligence · Computer Science 2025-08-22 Ziyuan Huang , Vishaldeep Kaur Sekhon , Roozbeh Sadeghian , Maria L. Vaida , Cynthia Jo , Doyle Ward , Vanni Bucci , John P. Haran

Large-language models have recently demonstrated impressive zero-shot capabilities in a variety of natural language tasks such as summarization, dialogue generation, and question-answering. Despite many promising applications in clinical…

Large Language Model (LLM)-based agents have demonstrated strong capabilities across a wide range of tasks, and their application in the medical domain holds particular promise due to the demand for high generalizability and reliance on…

Artificial Intelligence · Computer Science 2025-08-18 Yangyang Zhuang , Wenjia Jiang , Jiayu Zhang , Ze Yang , Joey Tianyi Zhou , Chi Zhang

Despite significant advancements in Large Language Models (LLMs) and Large Vision-Language Models (LVLMs), current models still face substantial challenges in handling complex, multi-turn, and visually-grounded tasks that demand deep…

Computation and Language · Computer Science 2025-08-22 Seungmin Han , Haeun Kwon , Ji-jun Park , Taeyang Yoon

In recent years, Large Language Models (LLMs) have demonstrated an impressive ability to encode knowledge during pre-training on large text corpora. They can leverage this knowledge for downstream tasks like question answering (QA), even in…

Computation and Language · Computer Science 2024-06-11 Juraj Vladika , Phillip Schneider , Florian Matthes

Vision-language pretraining (VLP) has emerged as a powerful paradigm in medical image analysis, enabling representation learning from large-scale image-text pairs without relying on expensive manual annotations. However, existing methods…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Xieji Li , Siyuan Yan , Yingsheng Liu , H. Peter Soyer , Monika Janda , Victoria Mar , Zongyuan Ge

Multimodal Large Language Models (MLLMs) excel in solving text-based mathematical problems, but they struggle with mathematical diagrams since they are primarily trained on natural scene images. For humans, visual aids generally enhance…

Computation and Language · Computer Science 2024-09-26 Wenwen Zhuang , Xin Huang , Xiantao Zhang , Jin Zeng

An ensemble of trained multimodal encoders and vision-language models (VLMs) has become a standard approach for visual question answering (VQA) tasks. However, such models often fail to produce responses with the detailed precision…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Rakesh Raj Madavan , Akshat Kaimal , Hashim Faisal , Chandrakala S

Multimodal Large Language Models (MLLMs) have become a powerful tool for integrating visual and textual information. Despite their exceptional performance on visual understanding benchmarks, measuring their ability to reason abstractly…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Nilay Yilmaz , Maitreya Patel , Yiran Lawrence Luo , Tejas Gokhale , Chitta Baral , Suren Jayasuriya , Yezhou Yang

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen