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The emergence of large language model (LLM)-based agents has significantly advanced the development of autonomous machine learning (ML) engineering. However, the dominant prompt-based paradigm exhibits limitations: smaller models lack the…

Computation and Language · Computer Science 2026-05-04 Zexi Liu , Jingyi Chai , Xinyu Zhu , Shuo Tang , Rui Ye , Bo Zhang , Lei Bai , Siheng Chen

The integration of deep learning-based glaucoma detection with large language models (LLMs) presents an automated strategy to mitigate ophthalmologist shortages and improve clinical reporting efficiency. However, applying general LLMs to…

Multiagent Systems · Computer Science 2025-12-18 Philip R. Liu , Sparsh Bansal , Jimmy Dinh , Aditya Pawar , Ramani Satishkumar , Shail Desai , Neeraj Gupta , Xin Wang , Shu Hu

United States healthcare systems are struggling to meet the growing demand for neurological care, particularly in Alzheimer's disease and related dementias (ADRD). Generative AI built on language models (LLMs) now enables agentic AI systems…

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Large Language Models (LLMs) are increasingly used as autonomous agents in complex, long-horizon applications, where effective memory is critical for sustained performance. Yet existing memory benchmarks are largely dialogue-centric, while…

Multimodal Large Language Models (MLLMs) have shown impressive capabilities in jointly understanding text, images, and videos, often evaluated via Visual Question Answering (VQA). However, even state-of-the-art MLLMs struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Alberto Compagnoni , Marco Morini , Sara Sarto , Federico Cocchi , Davide Caffagni , Marcella Cornia , Lorenzo Baraldi , Rita Cucchiara

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context…

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Computation and Language · Computer Science 2025-03-21 Xiangru Tang , Daniel Shao , Jiwoong Sohn , Jiapeng Chen , Jiayi Zhang , Jinyu Xiang , Fang Wu , Yilun Zhao , Chenglin Wu , Wenqi Shi , Arman Cohan , Mark Gerstein

Large Language Models (LLMs) have achieved remarkable reliability and advanced capabilities through extended test-time reasoning. However, extending these capabilities to Multi-modal Large Language Models (MLLMs) remains a significant…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Yuhao Dong , Zuyan Liu , Shulin Tian , Yongming Rao , Ziwei Liu

State-of-the-art large language models (LLMs) show high performance in general visual question answering. However, a fundamental limitation remains: current architectures lack the native 3D spatial reasoning required for direct analysis of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Ayhan Can Erdur , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C. Peeken

The creation of high-quality datasets to improve Large Language Model (LLM) reasoning remains a significant challenge, as current methods often suffer from generating low-quality/incorrect answers and limited information richness from…

Computation and Language · Computer Science 2026-01-09 Xianyang Liu , Yilin Liu , Shuai Wang , Hao Cheng , Andrew Estornell , Yuzhi Zhao , Jun Shu , Jiaheng Wei

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Effective diabetes management is crucial for maintaining health in diabetic patients. Large Language Models (LLMs) have opened new avenues for diabetes management, facilitating their efficacy. However, current LLM-based approaches are…

Computation and Language · Computer Science 2024-03-01 Mahyar Abbasian , Zhongqi Yang , Elahe Khatibi , Pengfei Zhang , Nitish Nagesh , Iman Azimi , Ramesh Jain , Amir M. Rahmani

The ability to organically reason over and with both text and images is a pillar of human intelligence, yet the ability of Multimodal Large Language Models (MLLMs) to perform such multimodal reasoning remains under-explored. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Yunzhuo Hao , Jiawei Gu , Huichen Will Wang , Linjie Li , Zhengyuan Yang , Lijuan Wang , Yu Cheng

Dermatological care via telemedicine often lacks the rich context of in-person visits. Clinicians must make diagnoses based on a handful of images and brief descriptions, without the benefit of physical exams, second opinions, or reference…

Artificial Intelligence · Computer Science 2025-08-27 Karishma Thakrar , Shreyas Basavatia , Akshay Daftardar

Large Language Models (LLMs) have attained human-level accuracy on medical question-answer (QA) benchmarks. However, their limitations in navigating open-ended clinical scenarios have recently been shown, raising concerns about the…

Computation and Language · Computer Science 2025-11-13 Jonathan Kim , Anna Podlasek , Kie Shidara , Feng Liu , Ahmed Alaa , Danilo Bernardo

With the increasing demand for step-wise, cross-modal, and knowledge-grounded reasoning, multimodal large language models (MLLMs) are evolving beyond the traditional fixed retrieve-then-generate paradigm toward more sophisticated agentic…

Artificial Intelligence · Computer Science 2026-03-03 Xuying Ning , Dongqi Fu , Tianxin Wei , Mengting Ai , Jiaru Zou , Ting-Wei Li , Hanghang Tong , Yada Zhu , Hendrik Hamann , Jingrui He

Having revolutionized natural language processing (NLP) applications, large language models (LLMs) are expanding into the realm of multimodal inputs. Owing to their ability to interpret images, multimodal LLMs (MLLMs) have been primarily…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Jusung Lee , Sungguk Cha , Younghyun Lee , Cheoljong Yang

Large Language Models (LLMs) have shown impressive capabilities in generating human-like responses. However, their lack of domain-specific knowledge limits their applicability in healthcare settings, where contextual and comprehensive…

Computation and Language · Computer Science 2024-03-14 Subash Neupane , Shaswata Mitra , Sudip Mittal , Noorbakhsh Amiri Golilarz , Shahram Rahimi , Amin Amirlatifi

Though Large Vision-Language Models (LVLMs) are being actively explored in medicine, their ability to conduct complex real-world telemedicine consultations combining accurate diagnosis with professional dialogue remains underexplored. This…

Human-Computer Interaction · Computer Science 2025-11-12 Ivan Sviridov , Amina Miftakhova , Artemiy Tereshchenko , Galina Zubkova , Pavel Blinov , Andrey Savchenko