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AI development environments are evolving into observability first platforms that integrate real time telemetry, prompt traces, and evaluation feedback into the developer workflow. This paper introduces telemetry aware integrated development…

Software Engineering · Computer Science 2025-06-16 Vincent Koc , Jacques Verre , Douglas Blank , Abigail Morgan

The Model Context Protocol (MCP) represents a significant advancement in AI-tool integration, enabling seamless communication between AI agents and external services. However, this connectivity introduces novel attack vectors that remain…

Cryptography and Security · Computer Science 2025-07-29 Nicola Croce , Tobin South

Large language models and autonomous AI agents have evolved rapidly, resulting in a diverse array of evaluation benchmarks, frameworks, and collaboration protocols. Driven by the growing need for standardized evaluation and integration, we…

Artificial Intelligence · Computer Science 2026-03-10 Mohamed Amine Ferrag , Norbert Tihanyi , Merouane Debbah

Addressing the challenge of multimodal data fusion in high-dimensional biomedical informatics, we propose MMCTOP, a MultiModal Clinical-Trial Outcome Prediction framework that integrates heterogeneous biomedical signals spanning (i)…

Machine Learning · Computer Science 2025-12-29 Carolina Aparício , Qi Shi , Bo Wen , Tesfaye Yadete , Qiwei Han

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

Cancer is a complex disease driven by genomic alterations, and tumor sequencing is becoming a mainstay of clinical care for cancer patients. The emergence of multi-institution sequencing data presents a powerful resource for learning…

Genomics · Quantitative Biology 2024-10-31 Yuan Chen , Ronglai Shen , Xiwen Feng , Katherine Panageas

Large language model (LLM)-based agents are increasingly used to perform complex, multi-step workflows in regulated settings such as compliance and due diligence. However, many agentic architectures rely primarily on prompt engineering of a…

Artificial Intelligence · Computer Science 2026-02-03 Ananya Joshi , Michael Rudow

Motivation: Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulators do not always take full advantage of modern hardware and often have a field-specific software design. Results:…

Model Context Protocol (MCP) is increasingly adopted for tool-integrated LLM agents, but its multi-layer design and third-party server ecosystem expand risks across tool metadata, untrusted outputs, cross-tool flows, multimodal inputs, and…

Cryptography and Security · Computer Science 2026-04-24 Run Hao , Zhuoran Tan

The rapid evolution of artificial intelligence (AI) has introduced AI agents as a disruptive paradigm across various industries, yet their application in machine translation (MT) remains underexplored. This paper describes and analyses the…

Computation and Language · Computer Science 2025-04-18 Vicent Briva-Iglesias

Large language models (LLMs) are increasingly envisioned as decision-support tools in clinical practice, yet safe clinical reasoning demands integrating heterogeneous knowledge bases -- trials, primary studies, regulatory documents, and…

Computation and Language · Computer Science 2025-05-22 Shan Chen , Pedro Moreira , Yuxin Xiao , Sam Schmidgall , Jeremy Warner , Hugo Aerts , Thomas Hartvigsen , Jack Gallifant , Danielle S. Bitterman

The rapid growth of scientific software has created practical barriers for bioinformatics research. Although powerful statistical, artificial intelligence (AI)-based methods are now widely available, their effective use is often hindered by…

Software Engineering · Computer Science 2026-04-24 Simon Süwer , Zoe Chervontseva , Kester Bagemihl , Jan Baumbach , Olga Tsoy , Andreas Maier

The rapid progress of Large Multimodal Models (LMMs) and cloud-based AI agents is transforming human-AI collaboration into bidirectional, multimodal interaction. However, existing codecs remain optimized for unimodal, one-way communication,…

Artificial Intelligence · Computer Science 2025-09-29 Qi Mao , Tinghan Yang , Jiahao Li , Bin Li , Libiao Jin , Yan Lu

The Model Context Protocol (MCP) has emerged as a de facto standard for integrating Large Language Models with external tools, yet no formal security analysis of the protocol specification exists. We present the first rigorous security…

Cryptography and Security · Computer Science 2026-01-27 Narek Maloyan , Dmitry Namiot

The integration of Large Language Models (LLMs) into network operations (AIOps) is hindered by two fundamental challenges: the stochastic grounding problem, where LLMs struggle to reliably parse unstructured, vendor-specific CLI output, and…

Networking and Internet Architecture · Computer Science 2026-02-02 Devansh Lodha , Mohit Panchal , Sameer G. Kulkarni

Bio-digital systems that merge microbial life with technology promise new modes of computation, combining biological adaptability with digital precision. Yet realizing this potential symbiotically -- where biological and digital agents…

Human-Computer Interaction · Computer Science 2026-01-23 Zoë Breed , Elvin Karana , Alessandro Bozzon , Katherine W. Song

Multi-agents systems communication is a technology, which provides a way for multiple interacting intelligent agents to communicate with each other and with environment. Multiple-agent systems are used to solve problems that are difficult…

Multiagent Systems · Computer Science 2017-03-01 S. Ponomarev , A. E. Voronkov

With the rise of LLMs, a large number of Model Context Protocol (MCP) services have emerged since the end of 2024. However, the effectiveness and efficiency of MCP servers have not been well studied. To study these questions, we propose an…

Information Retrieval · Computer Science 2025-04-21 Zhiling Luo , Xiaorong Shi , Xuanrui Lin , Jinyang Gao

AI for IT Operations (AIOps) aims to automate complex operational tasks, such as fault localization and root cause analysis, to reduce human workload and minimize customer impact. While traditional DevOps tools and AIOps algorithms often…

Artificial Intelligence · Computer Science 2025-01-14 Yinfang Chen , Manish Shetty , Gagan Somashekar , Minghua Ma , Yogesh Simmhan , Jonathan Mace , Chetan Bansal , Rujia Wang , Saravan Rajmohan

The Model Context Protocol (MCP) has rapidly become a de facto standard for connecting LLM-based agents with external tools via reusable MCP servers. In practice, however, server selection and onboarding rely heavily on free-text tool…

Software Engineering · Computer Science 2026-02-24 Peiran Wang , Ying Li , Yuqiang Sun , Chengwei Liu , Yang Liu , Yuan Tian