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Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Supply Chain Management requires addressing a variety of complex decision-making challenges, from sourcing strategies to planning and execution. Over the last few decades, advances in computation and information technologies have enabled…

Artificial Intelligence · Computer Science 2025-07-30 David Simchi-Levi , Konstantina Mellou , Ishai Menache , Jeevan Pathuri

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

Artificial Intelligence · Computer Science 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee

Advances in large language models (LLMs) provide new opportunities in healthcare for improved patient care, clinical decision-making, and enhancement of physician and administrator workflows. However, the potential of these models…

Computation and Language · Computer Science 2024-02-27 Salman Rahman , Lavender Yao Jiang , Saadia Gabriel , Yindalon Aphinyanaphongs , Eric Karl Oermann , Rumi Chunara

The job shop scheduling problem (JSSP) remains a significant hurdle in optimizing production processes. This challenge involves efficiently allocating jobs to a limited number of machines while minimizing factors like total processing time…

Artificial Intelligence · Computer Science 2024-08-14 Henrik Abgaryan , Ararat Harutyunyan , Tristan Cazenave

Fine-tuning large language models (LLMs) with limited data poses a practical challenge in low-resource languages, specialized domains, and constrained deployment settings. While pre-trained LLMs provide strong foundations, effective…

Computation and Language · Computer Science 2025-10-29 Marton Szep , Daniel Rueckert , Rüdiger von Eisenhart-Rothe , Florian Hinterwimmer

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

Large language model (LLM)-based systems are becoming increasingly popular for solving tasks by constructing executable workflows that interleave LLM calls, information retrieval, tool use, code execution, memory updates, and verification.…

Artificial Intelligence · Computer Science 2026-03-25 Ling Yue , Kushal Raj Bhandari , Ching-Yun Ko , Dhaval Patel , Shuxin Lin , Nianjun Zhou , Jianxi Gao , Pin-Yu Chen , Shaowu Pan

Medical large language models (LLMs) have gained popularity recently due to their significant practical utility. However, most existing research focuses on general medicine, and there is a need for in-depth study of LLMs in specific fields…

Computation and Language · Computer Science 2024-03-06 Zhonghai Wang , Jie Jiang , Yibing Zhan , Bohao Zhou , Yanhong Li , Chong Zhang , Liang Ding , Hua Jin , Jun Peng , Xu Lin , Weifeng Liu

Clinical patient notes are critical for documenting patient interactions, diagnoses, and treatment plans in medical practice. Ensuring accurate evaluation of these notes is essential for medical education and certification. However, manual…

Computation and Language · Computer Science 2024-01-25 Jingyu Xu , Yifeng Jiang , Bin Yuan , Shulin Li , Tianbo Song

Large Language Models (LLMs) have demonstrated remarkable language understanding and generation capabilities. However, training, deploying, and accessing these models pose notable challenges, including resource-intensive demands, extended…

Computation and Language · Computer Science 2024-01-31 Souvika Sarkar , Mohammad Fakhruddin Babar , Monowar Hasan , Shubhra Kanti Karmaker

We study clinical trial table reasoning, where answers are not directly stored in visible cells but must be reasoned from semantic understanding through normalization, classification, extraction, or lightweight domain reasoning. Motivated…

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Large language models (LLMs) have revolutionized applications such as code completion, chatbots, and online classification. To elevate user experiences, service level objectives (SLOs) serve as crucial benchmarks for assessing inference…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-13 Jinqi Huang , Yi Xiong , Xuebing Yu , Wenjie Huang , Entong Li , Li Zeng , Xin Chen

The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

Machine Learning · Computer Science 2025-07-31 Peng-Yi Wu , Pei-Cing Huang , Ting-Yu Chen , Chantung Ku , Ming-Yen Lin , Yihuang Kang

Modern deployments of Large Language Models (LLMs) increasingly require serving multiple models with diverse architectures, sizes, and specialization on shared, heterogeneous hardware. This setting introduces new challenges for resource…

Artificial Intelligence · Computer Science 2026-05-20 Mert Yildiz , Pietro Spadaccino , Alexey Rolich , Francesca Cuomo , Andrea Baiocchi

The language generation and reasoning capabilities of large language models (LLMs) have enabled conversational systems with impressive performance in a variety of tasks, from code generation, to composing essays, to passing STEM and legal…

Artificial Intelligence · Computer Science 2025-02-28 Konstantina Christakopoulou , Iris Qu , John Canny , Andrew Goodridge , Cj Adams , Minmin Chen , Maja Matarić

Optimization algorithms and large language models (LLMs) enhance decision-making in dynamic environments by integrating artificial intelligence with traditional techniques. LLMs, with extensive domain knowledge, facilitate intelligent…

Neural and Evolutionary Computing · Computer Science 2024-05-17 Sen Huang , Kaixiang Yang , Sheng Qi , Rui Wang

The growing need to integrate information from a large number of diverse sources poses significant scalability challenges for data integration systems. These systems often rely on manually written schema mappings, which are complex,…

Databases · Computer Science 2025-06-02 Christopher Buss , Mahdis Safari , Arash Termehchy , Stefan Lee , David Maier