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Cellular renewing active matter - assemblies of proliferating and apoptotic cells - underlies tissue homeostasis, morphogenesis, and clonal competition. Previous work in one-dimensional periodic systems identified a fitness advantage…

Soft Condensed Matter · Physics 2025-12-02 Patrick Zimmer , Philip Bittihn , Yoav G. Pollack

Using novel micro-printing techniques, we develop a versatile experimental setup that allows us to study how lateral confinement tames the active flows and defect properties of the microtubule/kinesin active nematic system. We demonstrate…

Implicit neural representations have emerged as a powerful approach for encoding complex geometries as continuous functions. These implicit models are widely used in computer vision and 3D content creation, but their integration into…

We introduce NeuralMLS, a space-based deformation technique, guided by a set of displaced control points. We leverage the power of neural networks to inject the underlying shape geometry into the deformation parameters. The goal of our…

Graphics · Computer Science 2022-06-14 Meitar Shechter , Rana Hanocka , Gal Metzer , Raja Giryes , Daniel Cohen-Or

Many living and physical systems such as cell aggregates, tissues or bacterial colonies behave as unconventional systems of particles that are strongly constrained by volume exclusion and shape interactions. Understanding how these…

Quantitative Methods · Quantitative Biology 2026-05-20 Antoine Diez , Jean Feydy

We propose a linear programming (LP) framework for steady-state diffusion and flux optimization on geometric networks. The state variable satisfies a discrete diffusion law on a weighted, oriented graph, where conductances are scaled by…

Optimization and Control · Mathematics 2025-11-06 Harbir Antil , Rainald Löhner , Felipe Pérez

Organoids are in vitro cellular collectives from which brain-like, or gut-like, or kidney-like structures emerge. To make quantitative predictions regarding the morphology and rheology of a cellular collective in its initial stages of…

Soft Condensed Matter · Physics 2023-01-12 Tao Zhang , J. M. Schwarz

Cells and tissues change shape both to carry out their function and during pathology. In most cases, these deformations are driven from within the systems themselves. This is permitted by a range of molecular actors, such as active…

Biological Physics · Physics 2022-10-18 Alexander Erlich , Jocelyn Étienne , Jonathan Fouchard , Tom Wyatt

We propose a PDE-constrained shape registration algorithm that captures the deformation and growth of biological tissue from imaging data. Shape registration is the process of evaluating optimum alignment between pairs of geometries through…

Biological Physics · Physics 2022-04-07 Aishwarya Pawar , Linlin Li , Arun K Gosain , David M Umulis , Adrian B Tepole

Recent biological experiments have shown that certain types of cells are able to move in structured and confined environment even without the activation of focal adhesion. Focusing on this particular phenomenon and based on previous works,…

Analysis of PDEs · Mathematics 2022-12-05 Chiara Giverso , Gaspard Jankowiak , Luigi Preziosi , Christian Schmeiser

Recent techniques have been successful in reconstructing surfaces as level sets of learned functions (such as signed distance fields) parameterized by deep neural networks. Many of these methods, however, learn only closed surfaces and are…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 David Palmer , Dmitriy Smirnov , Stephanie Wang , Albert Chern , Justin Solomon

The collective action of actively contractile units embedded in elastic biopolymer networks plays a crucial role in regulating the network's macroscopic mechanical response. Here, we investigate how the macroscopic boundary stress in model…

Soft Condensed Matter · Physics 2026-03-25 Abhinav Kumar , David A. Quint , Kinjal Dasbiswas

Grain boundary (GB) migration governs microstructure evolution and can mediate plastic deformation through sliding or shear coupling. Numerous experimental and numerical studies have reported a wide range of behaviors associated with…

Materials Science · Physics 2026-02-03 Brandon Runnels

Cells and microorganisms employ dynamic shape changes to enable steering and avoidance for efficient spatial exploration and collective organization. In contrast, active colloids, their synthetic counterparts, currently lack similar…

Soft Condensed Matter · Physics 2025-01-03 Stefania Ketzetzi , Lorenzo Caprini , Vivien Willems , Laura Alvarez , Hartmut Löwen , Lucio Isa

Active matter systems typically exhibit a trade-off between structural robustness and dynamical freedom, limiting independent control over structure and motion. Here, we show that encoding interactions in a shared field overcomes this…

Soft Condensed Matter · Physics 2026-04-16 Yuanmei Li , Rahil Valani

We investigate photo-responsive structure formation in a minimal model of dry active nematics. Combining microscopic simulations with the analysis of the corresponding hydrodynamic theory, we show that the system generically self-assembles…

Soft Condensed Matter · Physics 2026-05-29 Giuseppe Fava , Francesco Ginelli , Benoît Mahault

Collective cell motions underlie structure formation during embryonic development. Tissues exhibit emergent multicellular characteristics such as jamming, rigidity transitions, and glassy dynamics, but there remain questions about how those…

Biological Physics · Physics 2023-12-13 Evan Thomas , Sevan Hopyan

External fields can decidedly alter the free energy landscape of soft materials and can be exploited as a powerful tool for the assembly of targeted nanostructures and colloidal materials. Here, we use computer simulations to demonstrate…

Soft Condensed Matter · Physics 2019-02-08 Ahmad K. Omar , Yanze Wu , Zhen-Gang Wang , John F. Brady

Understanding the mechanical instabilities of two-dimensional membranes has strong connection to the subjects of structure instabilities, morphology control and materials failures. In this work, we investigate the plastic mechanism…

Soft Condensed Matter · Physics 2024-04-30 Honghui Sun , Zhenwei Yao

The macroscopic behaviour of active matter arises from nonequilibrium microscopic processes. In soft materials, active stresses typically drive macroscopic shape changes, which in turn alter the geometry constraining the microscopic…

Soft Condensed Matter · Physics 2024-11-26 Tim Dullweber , Roman Belousov , Anna Erzberger