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Biological tissues exhibit complex behaviors with their dynamics often resembling inert soft matter such as liquids, polymers, colloids, and liquid crystals. These analogies enable physics-based approaches for investigations of emergent…

Active solids consume energy to allow for actuation, shape change, and wave propagation not possible in equilibrium. Whereas active interfaces have been realized across many experimental systems, control of three-dimensional (3D) bulk…

Soft Condensed Matter · Physics 2022-03-23 Jack Binysh , Thomas R. Wilks , Anton Souslov

Active networks made of biopolymers and motor proteins are valuable bioinspired systems that have been used in the last decades to study the cytoskeleton and its self-organization under mechanical stimulation. Different techniques are…

Soft Condensed Matter · Physics 2023-05-15 Vahid Nasirimarekani , Olinka Ramìrez-Soto , Stefan Karpitschka , Isabella Guido

Plants are a paradigm for active shape control in response to stimuli. For instance, it is well-known that a tilted plant will eventually straighten vertically, demonstrating the influence of both an external stimulus, gravity, and an…

Biological Physics · Physics 2025-09-09 Hadrien Oliveri , Derek E. Moulton , Heather A. Harrington , Alain Goriely

The stability of the boundary between regenerating tissues is essential to the maintenance of their integrity and biological function. Stress is known to play an important role in the regulation of cell division, cell growth and cell death,…

Biological Physics · Physics 2024-11-20 Luis Gómez-Nava , Djamel Chekroun , Ioan Ionescu , Marc Durand

Convergent extension of epithelial tissue is a key motif of animal morphogenesis. On a coarse scale, cell motion resembles laminar fluid flow; yet in contrast to a fluid, epithelial cells adhere to each other and maintain the tissue layer…

Biological Physics · Physics 2024-10-04 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Biomaterial systems have allowed for the in vitro production of complex, emergent tissue behaviors that were not possible with conventional 2D culture systems allowing for analysis of the normal development as well as disease processes. We…

Tissues and Organs · Quantitative Biology 2019-10-16 Matthew S Hall , Joseph T Decker , Lonnie D Shea

Many complex structures and stochastic patterns emerge from simple kinetic rules and local interactions, and are governed by scale invariance properties in combination with effects of the global geometry. We consider systems that can be…

Statistical Mechanics · Physics 2013-09-17 Adnan Ali , Robin C. Ball , Stefan Grosskinsky , Ellak Somfai

Model-based manipulation of deformable objects has traditionally dealt with objects while neglecting their dynamics, thus mostly focusing on very lightweight objects at steady state. At the same time, soft robotic research has made…

Robotics · Computer Science 2025-10-21 Sebastien Tiburzio , Tomás Coleman , Daniel Feliu-Talegon , Cosimo Della Santina

Phase separation in passive systems leads to uncontrolled droplet growth, limiting structural control in soft materials and cells. We identify a generic mechanism to arrest coarsening based on chemical interconversion between molecular…

Soft Condensed Matter · Physics 2026-03-19 Florian Raßhofer , Erwin Frey

The directed migration of cells toward stiffer substrate regions or durotaxis is relevant to tissue development and tumor progression. Here, we introduce a phenomenological model for single cell durotaxis that incorporates both elastic…

Soft Condensed Matter · Physics 2024-12-24 Subhaya Bose , Haiqin Wang , Xinpeng Xu , Arvind Gopinath , Kinjal Dasbiswas

Predicting how the brain can be driven to specific states by means of internal or external control requires a fundamental understanding of the relationship between neural connectivity and activity. Network control theory is a powerful tool…

Neurons and Cognition · Quantitative Biology 2019-08-12 Teresa M. Karrer , Jason Z. Kim , Jennifer Stiso , Ari E. Kahn , Fabio Pasqualetti , Ute Habel , Danielle S. Bassett

Shapes of biological membranes are dynamically regulated in living cells. Although membrane shape deformation by proteins at thermal equilibrium has been extensively studied, nonequilibrium dynamics have been much less explored. Recently,…

Biological Physics · Physics 2020-11-19 Naoki Tamemoto , Hiroshi Noguchi

The automatic shape control of deformable objects is a challenging (and currently hot) manipulation problem due to their high-dimensional geometric features and complex physical properties. In this study, a new methodology to manipulate…

Robotics · Computer Science 2021-04-12 Jiaming Qi , Guangfu Ma , Peng Zhou , Haibo Zhang , Yueyong Lyu , David Navarro-Alarcon

The persistent dynamics in systems out of equilibrium, particularly those characterized by annihilation and creation of topological defects, is known to involve complicated spatiotemporal processes and is deemed difficult to control. Here…

Soft Condensed Matter · Physics 2022-11-22 Zhi-Feng Huang , Hartmut Löwen , Axel Voigt

We present a framework to take new measurements in nematic systems that contain active elements such as molecular motors. Spatio-temporal fields of stress, traction, velocity, pressure, and forces are estimated jointly from microscopy…

Soft Condensed Matter · Physics 2024-12-02 Aleix Boquet-Pujadas , Jérôme Hardouïn , Junhao Wen , Jordi Ignés-Mullol , Francesc Sagués

We study the dynamics of the boundary dilaton gravity coupled to N massles scalars. We rederive the boundary conditions of [1] and [3] in a way which makes the requirement of reparametrization invariance and role of conformal anomaly…

High Energy Physics - Theory · Physics 2015-06-26 Sumit R. Das , Sudipta Mukherji

We formulate the problem of material identification as a problem of optimal control in which the deformation of the specimen is the state variable and the unknown material law is the control variable. We assume that the material obeys…

Functional Analysis · Mathematics 2025-01-07 Sergio Conti , Michael Ortiz

Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

Soft Condensed Matter · Physics 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

In this paper, the dynamic of inertial capsules into microfluidic bifurcations is studied. The fluid evolution is based on the solution of the BGK -- lattice Boltzmann scheme including a forcing term accounting for immersed geometries. The…

Fluid Dynamics · Physics 2022-08-10 Alessandro Coclite , Marco D. de Tullio , Giuseppe Pascazio , Tiziano Politi
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