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Three-dimensional, time-dependent direct simulations of step emulsification micro-devices highlight two essential mechanisms for droplet formation: first, the onset of an adverse pressure gradient driving a back-flow of the continuous phase…

Computational Physics · Physics 2020-06-22 Andrea Montessori , Marco Lauricella , Sauro Succi , Elad Stolovicki , David A. Weitz

Microscopic active droplets are able to swim autonomously in viscous flows: this puzzling feature stems from solute exchanges with the surrounding fluid via surface reactions or their spontaneous solubilisation, and the interfacial flows…

Fluid Dynamics · Physics 2022-12-01 Sebastien Michelin

Active systems of self-propelled agents, e.g., birds, fish, and bacteria, can organize their collective motion into myriad autonomous behaviors. Ubiquitous in nature and across length scales, such phenomena are also amenable to artificial…

Soft Condensed Matter · Physics 2024-04-17 Yuchen Xi , Trevor J. Jones , Richard Huang , Tom Marzin , P. -T. Brun

Droplets are natural candidates for use as microfluidic reactors, if active control of their formation and transport can be achieved. We show here that localized heating from a laser can block the motion of a water-oil interface, acting as…

Fluid Dynamics · Physics 2015-06-26 C. N. Baroud , J. -P. Delville , F. Gallaire , R. Wunenburger

Directed assembly of colloids is an exciting field in materials science to form structures with new symmetries and responses. Fluid interfaces have been widely exploited to make densely packed ordered structures. We have been studying how…

Soft Condensed Matter · Physics 2017-07-03 Iris B. Liu , Giulia Bigazzi , Nima Sharifi-Mood , Lu Yao , Kathleen J. Stebe

Controlling interfaces of phase separating fluid mixtures is key to creating diverse functional soft materials. Traditionally, this is accomplished with surface-modifying chemical agents. Using experiment and theory, we study how mechanical…

Soft Condensed Matter · Physics 2022-08-15 Raymond Adkins , Itamar Kolvin , Zhihong You , Sven Witthaus , M. Cristina Marchetti , Zvonimir Dogic

We have developed a coupled level set and volume of fluid-based computational fluid dynamics model to analyze the droplet formation mechanism in a square flow-focusing microchannel. We demonstrate a flexible manipulation of droplet…

Fluid Dynamics · Physics 2025-10-09 Somasekhara Goud Sontti , Arnab Atta

The development of microfluidic devices is still hindered by the lack of robust fundamental building blocks that constitute any fluidic system. An attractive approach is optical actuation because light field interaction is contactless and…

Numerous cell-types have shown a remarkable ability to detect and move along gradients in stiffness of an underlying substrate -- a process known as durotaxis. The mechanisms underlying durotaxis are still unresolved, but generally believed…

Microfluidic droplet screens serve as an innovative platform for high-throughput biotechnology, enabling significant advancements in discovery, product optimization, and analysis. This review sheds light on the emerging trend of interaction…

Quantitative Methods · Quantitative Biology 2023-09-11 Carolus Vitalis , Tobias Wenzel

Droplet-based microfluidics has emerged as a powerful technology for the miniaturization and automation of biochemical assays. The replacement of surfactants by nanoparticles as interfacial stabilizers has gained increasing interest.…

Soft Condensed Matter · Physics 2019-06-21 Laura Andreina Chacon Orellana , Jean-Christophe Baret

Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

Soft Condensed Matter · Physics 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson

We report an experimental investigation of the spontaneous motion of liquid droplets on soft gels with a crosslinking gradient. By systematically adjusting the spatial difference in crosslinking density, we observed that millimeter-sized…

Soft Condensed Matter · Physics 2025-01-29 Weiwei Zhao , Wenjie Qian , Chang Xu , Qin Xu

The controllability of passive microparticles that are advected with the fluid flow generated by an actively controlled one is studied. The particles are assumed to be suspended in a viscous fluid and well separated so that the far-field…

Fluid Dynamics · Physics 2025-02-05 Henry Shum , Marta Zoppello , Michael Astwood , Marco Morandotti

Many biological, culinary, and engineering processes lead to the co-encapsulation of several soft particles within a liquid interface. In these situations the particles are bound together by the capillary forces that deform them and…

Soft Condensed Matter · Physics 2026-01-01 Shunsuke Saita , Finn Bastian Molzahn , Clara Delahousse , Julien Husson , Charles N. Baroud

Many complex wetting behaviors of fibrous materials are rooted in the behaviors of individual droplets attached to pairs of fibers. Here, we study the splitting of a droplet held between the tips of two cylindrical fibers. We discover a…

Phase separation in passive systems leads to uncontrolled droplet growth, limiting structural control in soft materials and cells. We identify a generic mechanism to arrest coarsening based on chemical interconversion between molecular…

Soft Condensed Matter · Physics 2026-03-19 Florian Raßhofer , Erwin Frey

Active fluids operate by constantly dissipating energy at the particle level to perform a directed motion, yielding dynamics and phases without any equilibrium equivalent. The emerging behaviors have been studied extensively, yet…

Statistical Mechanics · Physics 2020-02-03 Étienne Fodor , Takahiro Nemoto , Suriyanarayanan Vaikuntanathan

Active matter comprises self-driven units, such as bacteria and synthetic microswimmers, that can spontaneously form complex patterns and assemble into functional microdevices. These processes are possible thanks to the out-of-equilibrium…

Soft Condensed Matter · Physics 2021-11-17 Jens Grauer , Falko Schmidt , Jesus Pineda , Benjamin Midtvedt , Hartmut Löwen , Giovanni Volpe , Benno Liebchen

We study the interaction of small hydrophobic particles on the surface of an ultra-soft elastic gel, in which a small amount of elasticity of the medium balances the weights of the particles. The excess energy of the surface of the deformed…

Soft Condensed Matter · Physics 2014-06-09 Aditi Chakrabarti , Manoj K. Chaudhury