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Divergent brain connectivity is thought to underlie the behavioral and cognitive symptoms observed in many neurodevelopmental disorders. Quantifying divergence from neurotypical connectivity patterns offers a promising pathway to inform…
Domain adaptation is pivotal for enabling deep learning models to generalize across diverse domains, a task complicated by variations in presentation and cognitive nuances. In this paper, we introduce AD-Aligning, a novel approach that…
Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…
Although DNA foundation models have advanced the understanding of genomes, they still face significant challenges in the limited scale and diversity of genomic data. This limitation starkly contrasts with the success of natural language…
In structure-based drug design, accurately estimating the binding affinity between a candidate ligand and its protein receptor is a central challenge. Recent advances in artificial intelligence, particularly deep learning, have demonstrated…
Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…
Graph neural networks (GNNs) excel at predictive tasks on graph-structured data but often lack the ability to incorporate symbolic domain knowledge and perform general reasoning. Relational Bayesian Networks (RBNs), in contrast, enable…
Logic-based machine learning aims to learn general, interpretable knowledge in a data-efficient manner. However, labelled data must be specified in a structured logical form. To address this limitation, we propose a neural-symbolic learning…
Legal texts often contain computational legal clauses--provisions whose understanding requires complex logic. While frontier Large Reasoning Models (LRMs) can describe such clauses, building production-ready systems is limited by reasoning…
The trade-off between accuracy and interpretability has long been a challenge in machine learning (ML). This tension is particularly significant for emerging interpretable-by-design methods, which aim to redesign ML algorithms for…
Artificial neural networks (ANNs) are typically confined to accomplishing pre-defined tasks by learning a set of static parameters. In contrast, biological neural networks (BNNs) can adapt to various new tasks by continually updating the…
Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…
The last decades have seen a drastic improvement of Machine Learning (ML), mainly driven by Deep Learning (DL). However, despite the resounding successes of ML in many domains, the impossibility to provide guarantees of conformity and the…
Graph embedding has been widely applied in areas such as network analysis, social network mining, recommendation systems, and bioinformatics. However, current graph construction methods often require the prior definition of neighborhood…
Multi-agent reinforcement learning (MARL) is well-suited for runtime decision-making in optimizing the performance of systems where multiple agents coexist and compete for shared resources. However, applying common deep learning-based MARL…
We propose associative domain adaptation, a novel technique for end-to-end domain adaptation with neural networks, the task of inferring class labels for an unlabeled target domain based on the statistical properties of a labeled source…
Learning medical visual representations from paired images and reports is a promising direction in representation learning. However, current vision-language pretraining methods in the medical domain often simplify clinical reports into…
The computational capabilities of a neural network are widely assumed to be determined by its static architecture. Here we challenge this view by establishing that a fixed neural structure can operate in fundamentally different…
Graph Self-Supervised Learning (GSSL) has emerged as a powerful paradigm for generating high-quality representations for graph-structured data. While multi-scale graph contrastive learning has received increasing attention, many existing…
Uncertainty estimation remains a key challenge when adapting pre-trained language models to downstream classification tasks, with overconfidence often observed for difficult inputs. While predictive entropy provides a strong baseline for…