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Divergent brain connectivity is thought to underlie the behavioral and cognitive symptoms observed in many neurodevelopmental disorders. Quantifying divergence from neurotypical connectivity patterns offers a promising pathway to inform…

Neurons and Cognition · Quantitative Biology 2024-11-19 Rui Sherry Shen , Yusuf Osmanlıoğlu , Drew Parker , Darien Aunapu , Benjamin E. Yerys , Birkan Tunç , Ragini Verma

Domain adaptation is pivotal for enabling deep learning models to generalize across diverse domains, a task complicated by variations in presentation and cognitive nuances. In this paper, we introduce AD-Aligning, a novel approach that…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Zhuoying Li , Bohua Wan , Cong Mu , Ruzhang Zhao , Shushan Qiu , Chao Yan

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Although DNA foundation models have advanced the understanding of genomes, they still face significant challenges in the limited scale and diversity of genomic data. This limitation starkly contrasts with the success of natural language…

Genomics · Quantitative Biology 2024-02-14 Huixin Zhan , Ying Nian Wu , Zijun Zhang

In structure-based drug design, accurately estimating the binding affinity between a candidate ligand and its protein receptor is a central challenge. Recent advances in artificial intelligence, particularly deep learning, have demonstrated…

Biomolecules · Quantitative Biology 2025-09-18 Md Masud Rana , Farjana Tasnim Mukta , Duc D. Nguyen

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…

Machine Learning · Computer Science 2024-12-10 Zhepeng Wang , Runxue Bao , Yawen Wu , Guodong Liu , Lei Yang , Liang Zhan , Feng Zheng , Weiwen Jiang , Yanfu Zhang

Graph neural networks (GNNs) excel at predictive tasks on graph-structured data but often lack the ability to incorporate symbolic domain knowledge and perform general reasoning. Relational Bayesian Networks (RBNs), in contrast, enable…

Artificial Intelligence · Computer Science 2025-07-30 Raffaele Pojer , Andrea Passerini , Kim G. Larsen , Manfred Jaeger

Logic-based machine learning aims to learn general, interpretable knowledge in a data-efficient manner. However, labelled data must be specified in a structured logical form. To address this limitation, we propose a neural-symbolic learning…

Machine Learning · Computer Science 2023-01-06 Daniel Cunnington , Mark Law , Alessandra Russo , Jorge Lobo

Legal texts often contain computational legal clauses--provisions whose understanding requires complex logic. While frontier Large Reasoning Models (LRMs) can describe such clauses, building production-ready systems is limited by reasoning…

Computation and Language · Computer Science 2026-05-05 Stanisław Sójka , Witold Kowalczyk

The trade-off between accuracy and interpretability has long been a challenge in machine learning (ML). This tension is particularly significant for emerging interpretable-by-design methods, which aim to redesign ML algorithms for…

Machine Learning · Computer Science 2025-05-28 Geyu Liang , Senne Michielssen , Salar Fattahi

Artificial neural networks (ANNs) are typically confined to accomplishing pre-defined tasks by learning a set of static parameters. In contrast, biological neural networks (BNNs) can adapt to various new tasks by continually updating the…

Artificial Intelligence · Computer Science 2022-09-20 Fan Wang , Hao Tian , Haoyi Xiong , Hua Wu , Jie Fu , Yang Cao , Yu Kang , Haifeng Wang

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

The last decades have seen a drastic improvement of Machine Learning (ML), mainly driven by Deep Learning (DL). However, despite the resounding successes of ML in many domains, the impossibility to provide guarantees of conformity and the…

Machine Learning · Computer Science 2024-09-23 Arthur Ledaguenel , Céline Hudelot , Mostepha Khouadjia

Graph embedding has been widely applied in areas such as network analysis, social network mining, recommendation systems, and bioinformatics. However, current graph construction methods often require the prior definition of neighborhood…

Machine Learning · Computer Science 2025-10-08 S. Peng , L. Hu , W. Zhang , B. Jie , Y. Luo

Multi-agent reinforcement learning (MARL) is well-suited for runtime decision-making in optimizing the performance of systems where multiple agents coexist and compete for shared resources. However, applying common deep learning-based MARL…

We propose associative domain adaptation, a novel technique for end-to-end domain adaptation with neural networks, the task of inferring class labels for an unlabeled target domain based on the statistical properties of a labeled source…

Computer Vision and Pattern Recognition · Computer Science 2017-08-04 Philip Haeusser , Thomas Frerix , Alexander Mordvintsev , Daniel Cremers

Learning medical visual representations from paired images and reports is a promising direction in representation learning. However, current vision-language pretraining methods in the medical domain often simplify clinical reports into…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Wei Li , Xun Gong , Jiao Li , Xiaobin Sun

The computational capabilities of a neural network are widely assumed to be determined by its static architecture. Here we challenge this view by establishing that a fixed neural structure can operate in fundamentally different…

Neural and Evolutionary Computing · Computer Science 2025-09-24 Xia Chen

Graph Self-Supervised Learning (GSSL) has emerged as a powerful paradigm for generating high-quality representations for graph-structured data. While multi-scale graph contrastive learning has received increasing attention, many existing…

Machine Learning · Computer Science 2026-05-14 Mohamed Mahmoud Amar , Nairouz Mrabah , Mohamed Bouguessa , Abdoulaye Baniré Diallo

Uncertainty estimation remains a key challenge when adapting pre-trained language models to downstream classification tasks, with overconfidence often observed for difficult inputs. While predictive entropy provides a strong baseline for…

Computation and Language · Computer Science 2026-04-07 Artem Zabolotnyi , Roman Makarov , Mile Mitrovic , Polina Proskura , Oleg Travkin , Roman Alferov , Alexey Zaytsev
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