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MEG are non invasive neuroimaging techniques with excellent temporal and spatial resolution, crucial for studying brain function in dementia and Alzheimer Disease. They identify changes in brain activity at various Alzheimer stages,…

Machine Learning · Computer Science 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

B-cell epitopes play a key role in stimulating B-cells, triggering the primary immune response which results in antibody production as well as the establishment of long-term immunity in the form of memory cells. Consequently, being able to…

Quantitative Methods · Quantitative Biology 2021-03-23 Bhargab Ghoshal , Biraja Ghoshal , Stephen Swift , Allan Tucker

The rise of Antimicrobial Resistance, particularly Multi-Drug Resistance (MDR), presents a critical challenge for clinical decision-making due to limited treatment options and delays in conventional susceptibility testing. This study…

Machine Learning · Computer Science 2026-03-03 Santanam Wishal , Riad Sahara

Identifying important biomarkers that are predictive for cancer patients' prognosis is key in gaining better insights into the biological influences on the disease and has become a critical component of precision medicine. The emergence of…

Methodology · Statistics 2016-03-22 Hyokyoung Grace Hong , Jian Kang , Yi Li

The so-called gut-brain axis has stimulated extensive research on microbiomes. One focus is to assess the association between certain clinical outcomes and the relative abundances of gut microbes, which can be presented as sub-compositional…

Methodology · Statistics 2020-06-02 Xiaokang Liu , Xiaomei Cong , Gen Li , Kendra Maas , Kun Chen

Breast cancer remains a significant global health challenge, with prognosis and treatment decisions largely dependent on clinical characteristics. Accurate prediction of patient outcomes is crucial for personalized treatment strategies.…

Transcranial photobiomodulation (tPBM) therapy is an emerging, non-invasive neuromodulation technique that has demonstrated considerable potential in the field of neuropsychiatric disorders. Several studies have found that pulsed wave (PW)…

Neurons and Cognition · Quantitative Biology 2025-12-02 Jiangshan He , Hui Xie , Yuqiang Yang , Chunli Jia , Dan Liang , Lianghua Zhang , Xiaoyu Wang , Tianyi Luo , Zexiao Dong , Huiting Yang , Zhen Yuan , Mingzhe Jiang , Xueli Chen

Identifying predictive covariates, which forecast individual treatment effectiveness, is crucial for decision-making across different disciplines such as personalized medicine. These covariates, referred to as biomarkers, are extracted from…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Shuhan Xiao , Lukas Klein , Jens Petersen , Philipp Vollmuth , Paul F. Jaeger , Klaus H. Maier-Hein

Cardiovascular diseases are the most common causes of death around the world. To detect and treat heart-related diseases, continuous Blood Pressure (BP) monitoring along with many other parameters are required. Several invasive and…

Readmission prediction is a critical but challenging clinical task, as the inherent relationship between high-dimensional covariates and readmission is complex and heterogeneous. Despite this complexity, models should be interpretable to…

Methodology · Statistics 2025-07-10 Wei Wang , Angela Bailey , Christopher Tignanelli , Jared D. Huling

Rapid and non-destructive assessment of milk quality is crucial to ensuring both nutritional value and food safety. In this study, we investigated the potential of visible and hyperspectral imaging as cost-effective and quick-response…

Bioelectrical properties of cells such as relative permittivity, conductivity, and characteristic time constants vary significantly between healthy and malignant cells across different frequencies. These distinctions provide a promising…

Signal Processing · Electrical Eng. & Systems 2026-03-16 Shadeeb Hossain

Bipolar Disorder (BD) is a complex disease. It is heterogeneous, both at the phenotypic and genetic level, although the extent and impact of this heterogeneity is not fully understood. In this paper, we leverage recent advances in…

Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…

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Photoplethysmography (PPG) is emerging as a crucial tool for monitoring human hemodynamics, with recent studies highlighting its potential in assessing vascular aging through deep learning. However, real-world age distributions are often…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Guangkun Nie , Qinghao Zhao , Gongzheng Tang , Jun Li , Shenda Hong

Randomized controlled trials estimate average treatment effects, but treatment response heterogeneity motivates personalized approaches. A critical question is whether statistically detectable heterogeneity translates into improved…

Machine Learning · Computer Science 2026-02-10 Cristian Minoccheri , Sophia Tesic , Kayvan Najarian , Ryan Stidham

Background: Accurate week-ahead forecasts of continuous glucose monitoring (CGM) derived metrics could enable proactive diabetes management, but relative performance of modern tabular learning approaches is incompletely defined. Methods: We…

Other Quantitative Biology · Quantitative Biology 2026-01-05 Simon Lebech Cichosz , Stine Hangaard , Thomas Kronborg , Peter Vestergaard , Morten Hasselstrøm Jensen

Speech impairments are prevalent biomarkers for Parkinson's Disease (PD), motivating the development of diagnostic techniques using speech data for clinical applications. Although deep acoustic features have shown promise for PD…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-01 Emmy Postma , Cristian Tejedor-Garcia

Randomized A/B tests within online learning platforms represent an exciting direction in learning sciences. With minimal assumptions, they allow causal effect estimation without confounding bias and exact statistical inference even in small…

Methodology · Statistics 2023-06-13 Adam C. Sales , Ethan B. Prihar , Johann A. Gagnon-Bartsch , Neil T. Heffernan

A lot of time is spent searching for the most performing data mining algorithms applied in clinical diagnosis. The study set out to identify the most performing predictive data mining algorithms applied in the diagnosis of…

Machine Learning · Computer Science 2015-01-06 Kwetishe Danjuma , Adenike O. Osofisan