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The delayed access to specialized psychiatric assessments and care for patients at risk of suicidal tendencies in emergency departments creates a notable gap in timely intervention, hindering the provision of adequate mental health support…

We present constraints on the baryonic matter density parameter, $\Omega_b$, within the framework of the $\Lambda$CDM model. Our analysis utilizes observational data on the effective optical depth from high-redshift quasars. To parameterize…

Cosmology and Nongalactic Astrophysics · Physics 2025-01-31 Wen-Fei Liu , Yuan-Bo Xie , Zhi-E Liu , Jin Qin , Kang Jiao , Dong-Yao Zhao , Tong-Jie Zhang

Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…

Quantitative Methods · Quantitative Biology 2025-05-23 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Photoplethysmography (PPG) signals encode information about relative changes in blood volume that can be used to assess various aspects of cardiac health non-invasively, e.g.\ to detect atrial fibrillation (AF) or predict blood pressure…

Machine Learning · Computer Science 2025-05-19 Ciaran Bench , Vivek Desai , Mohammad Moulaeifard , Nils Strodthoff , Philip Aston , Andrew Thompson

At the time of diagnosis, prostate cancer can appear deceptively mild or already display signs of widespread disease. Predicting long-term outcomes is often uncertain. This research focused on measuring CD276/B7-H3, an immune checkpoint…

Quantitative Methods · Quantitative Biology 2025-08-14 Adam Yusuf , Paramahansa Pramanik

Most pregnancies and births result in a good outcome, but complications are not uncommon and when they do occur, they can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve…

Clinical decision support using data mining techniques offers more intelligent way to reduce the decision error in the last few years. However, clinical datasets often suffer from high missingness, which adversely impacts the quality of…

Machine Learning · Computer Science 2020-11-20 Xuetong Wu , Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Zobaida Edib , Michelle Peate

Calibrated probability outputs of trained classifiers are increasingly used as inputs to downstream regression estimands such as effects, prevalences, or disparities for a latent group observed only on a small labelled subset. A standard…

Methodology · Statistics 2026-05-14 Marcell T. Kurbucz

Background. Real-world data show that approximately 50% of psoriasis patients treated with a biologic agent will discontinue the drug because of loss of efficacy. History of previous therapy with another biologic, female sex and obesity…

Machine Learning · Statistics 2019-08-27 Sepideh Emam , Amy X. Du , Philip Surmanowicz , Simon F. Thomsen , Russ Greiner , Robert Gniadecki

Our knowledge of the organisation of the human brain at the population-level is yet to translate into power to predict functional differences at the individual-level, limiting clinical applications, and casting doubt on the generalisability…

Neurons and Cognition · Quantitative Biology 2024-04-04 James K Ruffle , Robert J Gray , Samia Mohinta , Guilherme Pombo , Chaitanya Kaul , Harpreet Hyare , Geraint Rees , Parashkev Nachev

We describe the Bedside Patient Rescue (BPR) project, the goal of which is risk prediction of adverse events for non-ICU patients using ~200 variables (vitals, lab results, assessments, ...). There are several missing predictor values for…

Breast cancer is the most common cancers and early detection from mammography screening is crucial in improving patient outcomes. Assessing mammographic breast density is clinically important as the denser breasts have higher risk and are…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Charles Lu , Ken Chang , Praveer Singh , Jayashree Kalpathy-Cramer

As we gain access to a greater depth and range of health-related information about individuals, three questions arise: (1) Can we build better models to predict individual-level risk of ill health? (2) How much data do we need to…

Machine Learning · Statistics 2021-04-27 Mark Green

As machine learning models are increasingly deployed in high-stakes domains, the need for interpretability has grown to meet strict regulatory and accountability constraints. Despite this interest, systematic evaluations of inherently…

Machine Learning · Computer Science 2026-03-27 Mattia Billa , Giovanni Orlandi , Veronica Guidetti , Federica Mandreoli

Diabetes is a chronic metabolic disease characterized by elevated blood glucose levels, leading to complications like heart disease, kidney failure, and nerve damage. Accurate state-level predictions are vital for effective healthcare…

Machine Learning · Computer Science 2025-06-18 Vuong M. Ngo , Tran Quang Vinh , Patricia Kearney , Mark Roantree

The proliferation of early diagnostic technologies, including self-monitoring systems and wearables, coupled with the application of these technologies on large segments of healthy populations may significantly aggravate the problem of…

Machine Learning · Computer Science 2021-07-23 Anna Fedyukova , Douglas Pires , Daniel Capurro

Caco-2 permeability serves as a critical in vitro indicator for predicting the oral absorption of drug candidates during early-stage drug discovery. To enhance the accuracy and efficiency of computational predictions, we systematically…

Quantitative Methods · Quantitative Biology 2025-06-11 Huong Van Le , Weibin Ren , Junhong Kim , Yukyung Yun , Young Bin Park , Young Jun Kim , Bok Kyung Han , Inho Choi , Jong IL Park , Hwi-Yeol Yun , Jae-Mun Choi

Predictive modelling is vital to guide preventive efforts. Whilst large-scale prospective cohort studies and a diverse toolkit of available machine learning (ML) algorithms have facilitated such survival task efforts, choosing the…

Early detection of chronic diseases is beneficial to healthcare by providing a golden opportunity for timely interventions. Although numerous prior studies have successfully used machine learning (ML) models for disease diagnoses, they…

Computers and Society · Computer Science 2024-10-07 Di Wang , Yidan Hu , Eng Sing Lee , Hui Hwang Teong , Ray Tian Rui Lai , Wai Han Hoi , Chunyan Miao

Background: Photoplethysmography (PPG), increasingly available through wearable devices, provides a non-invasive means of monitoring human hemodynamics. In this study, we introduce artificial intelligence-derived photoplethysmography…

Signal Processing · Electrical Eng. & Systems 2025-09-26 Guangkun Nie , Qinghao Zhao , Gongzheng Tang , Yaxin Li , Shenda Hong
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