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Effective analysis in neuroscience benefits significantly from robust conceptual frameworks. Traditional metrics of interbrain synchrony in social neuroscience typically depend on fixed, correlation-based approaches, restricting their…

Neurons and Cognition · Quantitative Biology 2025-12-01 Nicolás Hinrichs , Noah Guzmán , Melanie Weber

Despite the progress in deep learning networks, efficient learning at the edge (enabling adaptable, low-complexity machine learning solutions) remains a critical need for defense and commercial applications. We envision a pipeline to…

Unlike the von Neumann architecture, which separates computation from memory, the brain tightly integrates them, an organization that large language models increasingly resemble. The crucial difference lies in the ratio of energy spent on…

Hardware Architecture · Computer Science 2026-03-30 Wonsuk Lee , Jehoshua Bruck

What is it about human brains that allows us to reason symbolically whereas most other animals cannot? There is evidence that dynamic binding, the ability to combine neurons into groups on the fly, is necessary for symbolic thought, but…

Neural and Evolutionary Computing · Computer Science 2025-08-22 John E. Hummel , Rachel F. Heaton

We propose a data-driven approach to represent neuronal network dynamics as a Probabilistic Graphical Model (PGM). Our approach learns the PGM structure by employing dimension reduction to network response dynamics evoked by stimuli applied…

Neurons and Cognition · Quantitative Biology 2017-11-02 Hexuan Liu , Jimin Kim , Eli Shlizerman

The design of artificial neural networks (ANNs) is inspired by the structure of the human brain, and in turn, ANNs offer a potential means to interpret and understand brain signals. Existing methods primarily align brain signals with…

Neurons and Cognition · Quantitative Biology 2025-10-08 Yang Xiao , Wang Lu , Jie Ji , Ruimeng Ye , Gen Li , Xiaolong Ma , Bo Hui

Mapping the connectivity of neurons in the brain (i.e., connectomics) is a challenging problem due to both the number of connections in even the smallest organisms and the nanometer resolution required to resolve them. Because of this,…

Neurons and Cognition · Quantitative Biology 2014-09-08 Ting Zhao , Stephen M Plaza

We present an account of neuroplasticity with respect to cell-internal processing pathways in relation to membrane and synaptic plasticity. We think traditional synapse-centric, weight-based models of memorization are not sufficient or…

Neurons and Cognition · Quantitative Biology 2026-04-27 Gabriele Scheler

Darwinian evolution tends to produce energy-efficient outcomes. On the other hand, energy limits computation, be it neural and probabilistic or digital and logical. Taking a particular energy-efficient viewpoint, we define neural…

Neurons and Cognition · Quantitative Biology 2021-04-05 William B Levy , Victoria G. Calvert

This paper formulates a generalized classification algorithm with an application to classifying (or `decoding') neural activity in the brain. Medical doctors and researchers have long been interested in how brain activity correlates to body…

Optimization and Control · Mathematics 2015-03-17 Cary Humber , Kazufumi Ito , Chad Bouton

Understanding the functional architecture of the brain in terms of networks is becoming increasingly common. In most fMRI applications functional networks are assumed to be stationary, resulting in a single network estimated for the entire…

Learning requires the traversal of inherently distinct cognitive states to produce behavioral adaptation. Yet, tools to explicitly measure these states with non-invasive imaging -- and to assess their dynamics during learning -- remain…

For constructing neuronal network models computational neuroscientists have access to wide-ranging anatomical data that nevertheless tend to cover only a fraction of the parameters to be determined. Finding and interpreting the most…

The brain forms and stores distributed representations from sparse external input that compete for neuronal resources with already stored memory traces. It is unclear what dynamical properties of neural systems allow formation and…

Neurons and Cognition · Quantitative Biology 2018-02-08 Quinton M Skilling , Daniel Maruyama , Nicolette Ognjanovski , Sara J Aton , Michal Zochowski

Understanding the complexity of biological neural networks like the human brain is one of the scientific challenges of our century. The organization of the brain can be described at different levels, ranging from small neural networks to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Stefano De Blasi

This chapter sheds light on the synaptic organization of the brain from the perspective of computational neuroscience. It provides an introductory overview on how to account for empirical data in mathematical models, implement such models…

Spiking neural networks (SNNs) communicate via discrete spikes in time rather than continuous activations. Their event-driven nature offers advantages for temporal processing and energy efficiency on resource-constrained hardware, but…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Karol C. Jurzec , Tomasz Szydlo , Maciej Wielgosz

The brain structural connectome is generated by a collection of white matter fiber bundles constructed from diffusion weighted MRI (dMRI), acting as highways for neural activity. There has been abundant interest in studying how the…

Methodology · Statistics 2022-11-03 Didong Li , Phuc Nguyen , Zhengwu Zhang , David B Dunson

Artificial Neural Networks (ANNs) inspired by biology are beginning to be widely used to model behavioral and neural data, an approach we call neuroconnectionism. ANNs have been lauded as the current best models of information processing in…

Memory is often defined as the mental capacity of retaining information about facts, events, procedures and more generally about any type of previous experience. Memories are remembered as long as they influence our thoughts, feelings, and…

Neurons and Cognition · Quantitative Biology 2017-06-16 Stefano Fusi