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Multimodal semantic understanding often has to deal with uncertainty, which means the obtained messages tend to refer to multiple targets. Such uncertainty is problematic for our interpretation, including inter- and intra-modal uncertainty.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Yatai Ji , Junjie Wang , Yuan Gong , Lin Zhang , Yanru Zhu , Hongfa Wang , Jiaxing Zhang , Tetsuya Sakai , Yujiu Yang

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

Quantitative Methods · Quantitative Biology 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

Multimodal deep learning holds promise for improving clinical prediction by integrating diverse patient data, including text, imaging, time-series, and structured demographics. Contrastive learning facilitates this integration by producing…

Machine Learning · Computer Science 2025-07-08 Michal Golovanevsky , Pranav Mahableshwarkar , Carsten Eickhoff , Ritambhara Singh

Medical image segmentation aims to identify anatomical structures at the voxel-level. Segmentation accuracy relies on distinguishing voxel differences. Compared to advancements achieved in studies of the inter-class variance, the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Yali Bi , Enyu Che , Yinan Chen , Yuanpeng He , Jingwei Qu

Semi-supervised learning addresses the issue of limited annotations in medical images effectively, but its performance is often inadequate for complex backgrounds and challenging tasks. Multi-modal fusion methods can significantly improve…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Dongdong Meng , Sheng Li , Hao Wu , Guoping Wang , Xueqing Yan

Multimodal learning typically relies on the assumption that all modalities are fully available during both the training and inference phases. However, in real-world scenarios, consistently acquiring complete multimodal data presents…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Donggeun Kim , Taesup Kim

Vision-Language Pre-training (VLP) has shown the merits of analysing medical images, by leveraging the semantic congruence between medical images and their corresponding reports. It efficiently learns visual representations, which in turn…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Xiaoxuan He , Yifan Yang , Xinyang Jiang , Xufang Luo , Haoji Hu , Siyun Zhao , Dongsheng Li , Yuqing Yang , Lili Qiu

Large-scale multi-modal deep learning models have revolutionized domains such as healthcare, highlighting the importance of computational power. However, in resource-constrained regions like Low and Middle-Income Countries (LMICs), limited…

Vision-language models (VLMs), such as CLIP, have gained popularity for their strong open vocabulary classification performance, but they are prone to assigning high confidence scores to misclassifications, limiting their reliability in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Zhenxiang Lin , Maryam Haghighat , Will Browne , Dimity Miller

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

Multimodal approaches that integrate histology and genomics hold strong potential for precision oncology. However, phenotypic and genotypic heterogeneity limits the quality of intra-modal representations and hinders effective inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Yupei Zhang , Yating Huang , Wanming Hu , Lequan Yu , Hujun Yin , Chao Li

Deep learning and multi-modal fusion have demonstrated transformative potential in medical diagnosis by integrating diverse data sources. However, accurate prognosis for ischemic stroke remains challenging due to limitations in existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Liren Chen , Lidong Sun , Mingyan Huang , Junzhe Tang , Yinghui Zhu , Guanjie Wang , Yiqing Xia , Ting Xiao

Chest X-ray images are commonly used for predicting acute and chronic cardiopulmonary conditions, but efforts to integrate them with structured clinical data face challenges due to incomplete electronic health records (EHR). This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Mai A. Shaaban , Adnan Khan , Mohammad Yaqub

Recent advances in multimodal large language models have enabled unified processing of visual and textual inputs, offering promising applications in general-purpose medical AI. However, their ability to generalize compositionally across…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Pooja Singh , Siddhant Ujjain , Tapan Kumar Gandhi , Sandeep Kumar

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

In recent years, the growing demand for medical imaging diagnosis has placed a significant burden on radiologists. As a solution, Medical Vision-Language Pre-training (Med-VLP) methods have been proposed to learn universal representations…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Zhang , Yan Yang , Jun Yu , Hanliang Jiang , Jianping Fan , Qingming Huang , Weidong Han

Medical image segmentation is more clinically valuable when it supports diagnosis rather than merely producing lesion masks. However, diagnostically relevant lesion cues are often subtle and localized, while existing models may be…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Fengyi Zhang , Xujie Zeng , Mohan Liu , Zengyi Wang , Yalong Jiang

With recent advancements in Large Multimodal Models (LMMs) across various domains, a novel prompting method called visual referring prompting has emerged, showing significant potential in enhancing human-computer interaction within…

Computer Vision and Pattern Recognition · Computer Science 2023-12-08 Zongjie Li , Chaozheng Wang , Chaowei Liu , Pingchuan Ma , Daoyuan Wu , Shuai Wang , Cuiyun Gao

Probabilistic embeddings have proven useful for capturing polysemous word meanings, as well as ambiguity in image matching. In this paper, we study the advantages of probabilistic embeddings in a cross-modal setting (i.e., text and images),…

Machine Learning · Computer Science 2022-04-21 Leila Pishdad , Ran Zhang , Konstantinos G. Derpanis , Allan Jepson , Afsaneh Fazly

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these…