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Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 David Restrepo , Ira Ktena , Maria Vakalopoulou , Stergios Christodoulidis , Enzo Ferrante

Content-based medical image retrieval is an important diagnostic tool that improves the explainability of computer-aided diagnosis systems and provides decision making support to healthcare professionals. Medical imaging data, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Yunyan Xing , Benjamin J. Meyer , Mehrtash Harandi , Tom Drummond , Zongyuan Ge

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Deep learning offers transformative potential in medical imaging, yet its clinical adoption is frequently hampered by challenges such as data scarcity, distribution shifts, and the need for robust task generalization. Prompt-based…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Hao Yang , Xinlong Liang , Zhang Li , Yue Sun , Zheyu Hu , Xinghe Xie , Behdad Dashtbozorg , Jincheng Huang , Shiwei Zhu , Luyi Han , Jiong Zhang , Shanshan Wang , Ritse Mann , Qifeng Yu , Tao Tan

Medical image analysis increasingly relies on the integration of multiple imaging modalities to capture complementary anatomical and functional information, enabling more accurate diagnosis and treatment planning. Achieving aligned feature…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Yunhao Liu , Suyang Xi , Shiqi Liu , Hong Ding , Chicheng Jin , Chong Zhong , Junjun He , Catherine C. Liu , Yiqing Shen

Joint image-text embedding extracted from medical images and associated contextual reports is the bedrock for most biomedical vision-and-language (V+L) tasks, including medical visual question answering, clinical image-text retrieval,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Yikuan Li , Hanyin Wang , Yuan Luo

Modeling multi-modal time-series data is critical for capturing system-level dynamics, particularly in biosignals where modalities such as ECG, PPG, EDA, and accelerometry provide complementary perspectives on interconnected physiological…

Machine Learning · Computer Science 2025-10-14 Wanting Mao , Maxwell A Xu , Harish Haresamudram , Mithun Saha , Santosh Kumar , James Matthew Rehg

Existing machine learning methods for molecular (e.g., gene) embeddings are restricted to specific tasks or data modalities, limiting their effectiveness within narrow domains. As a result, they fail to capture the full breadth of gene…

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single…

Machine Learning · Computer Science 2025-05-13 Fergus Imrie , Stefan Denner , Lucas S. Brunschwig , Klaus Maier-Hein , Mihaela van der Schaar

Cross-modal retrieval methods build a common representation space for samples from multiple modalities, typically from the vision and the language domains. For images and their captions, the multiplicity of the correspondences makes the…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Sanghyuk Chun , Seong Joon Oh , Rafael Sampaio de Rezende , Yannis Kalantidis , Diane Larlus

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Taha Koleilat , Hojat Asgariandehkordi , Omid Nejati Manzari , Berardino Barile , Yiming Xiao , Hassan Rivaz

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Obtaining large pre-trained models that can be fine-tuned to new tasks with limited annotated samples has remained an open challenge for medical imaging data. While pre-trained deep networks on ImageNet and vision-language foundation models…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Duy M. H. Nguyen , Hoang Nguyen , Nghiem T. Diep , Tan N. Pham , Tri Cao , Binh T. Nguyen , Paul Swoboda , Nhat Ho , Shadi Albarqouni , Pengtao Xie , Daniel Sonntag , Mathias Niepert

Vision-language models pre-trained on large scale of unlabeled biomedical images and associated reports learn generalizable semantic representations. These multi-modal representations can benefit various downstream tasks in the biomedical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Xinliu Zhong , Kayhan Batmanghelich , Li Sun

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Large Multimodal Models (LMMs) have shown remarkable progress in medical Visual Question Answering (Med-VQA), achieving high accuracy on existing benchmarks. However, their reliability under robust evaluation is questionable. This study…

Artificial Intelligence · Computer Science 2025-06-12 Qianqi Yan , Xuehai He , Xiang Yue , Xin Eric Wang

Histo-genomic multimodal survival prediction has garnered growing attention for its remarkable model performance and potential contributions to precision medicine. However, a significant challenge in clinical practice arises when only…

Machine Learning · Computer Science 2025-03-17 Fengchun Liu , Linghan Cai , Zhikang Wang , Zhiyuan Fan , Jin-gang Yu , Hao Chen , Yongbing Zhang

Multi-modal fusion approaches aim to integrate information from different data sources. Unlike natural datasets, such as in audio-visual applications, where samples consist of "paired" modalities, data in healthcare is often collected…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Nasir Hayat , Krzysztof J. Geras , Farah E. Shamout

Simulation-based Medical Education (SBME) has been developed as a cost-effective means of enhancing the diagnostic skills of novice physicians and interns, thereby mitigating the need for resource-intensive mentor-apprentice training.…

Human-Computer Interaction · Computer Science 2023-07-25 Yang Ouyang , Yuchen Wu , He Wang , Chenyang Zhang , Furui Cheng , Chang Jiang , Lixia Jin , Yuanwu Cao , Quan Li