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Incremental learning aims to enable models to continuously acquire knowledge from evolving data streams while preserving previously learned capabilities. While current research predominantly focuses on unimodal incremental learning and…

Machine Learning · Computer Science 2025-04-21 Yaguang Song , Xiaoshan Yang , Dongmei Jiang , Yaowei Wang , Changsheng Xu

In real-world multimodal applications, systems usually need to comprehend arbitrarily combined and interleaved multimodal inputs from users, while also generating outputs in any interleaved multimedia form. This capability defines the goal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yanlin Li , Minghui Guo , Kaiwen Zhang , Shize Zhang , Yiran Zhao , Haodong Li , Congyue Zhou , Weijie Zheng , Yushen Yan , Shengqiong Wu , Wei Ji , Lei Cui , Furu Wei , Hao Fei , Mong-Li Lee , Wynne Hsu

For machine learning-based prognosis and diagnosis of rare diseases, such as pediatric brain tumors, it is necessary to gather medical imaging data from multiple clinical sites that may use different devices and protocols. Deep…

Brain tumor segmentation requires accurate identification of hierarchical regions including whole tumor (WT), tumor core (TC), and enhancing tumor (ET) from multi-sequence magnetic resonance imaging (MRI) images. Due to tumor tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Mingda Zhang , Yuyang Zheng , Ruixiang Tang , Jingru Qiu , Haiyan Ding

Synthetic neuroimaging data can mitigate critical limitations of real-world datasets, including the scarcity of rare phenotypes, domain shifts across scanners, and insufficient longitudinal coverage. However, existing generative models…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Fabian Bongratz , Yitong Li , Sama Elbaroudy , Christian Wachinger

The clinical adoption of artificial intelligence (AI) in medical imaging requires models that are both diagnostically accurate and interpretable to clinicians. While current multimodal biomedical foundation models prioritize performance,…

The human brain is a complex, dynamic network, which is commonly studied using functional magnetic resonance imaging (fMRI) and modeled as network of Regions of interest (ROIs) for understanding various brain functions. Recent studies…

Quantitative Methods · Quantitative Biology 2024-06-26 Yifan Yang , Yutong Mao , Xufu Liu , Xiao Liu

Physiological signals such as electrocardiograms (ECG) and electroencephalograms (EEG) provide complementary insights into human health and cognition, yet multi-modal integration is challenging due to limited multi-modal labeled data, and…

Naturalistic fMRI characterizes the brain as a dynamic predictive engine driven by continuous sensory streams. However, modeling the causal forward evolution in realistic neural simulation is impeded by the timescale mismatch between…

Neurons and Cognition · Quantitative Biology 2026-02-05 Xuanhua Yin , Runkai Zhao , Lina Yao , Weidong Cai

In this work, we propose a simple transformer-based baseline for multimodal molecular representation learning, integrating three distinct modalities: SMILES strings, 2D graph representations, and 3D conformers of molecules. A key aspect of…

Machine Learning · Computer Science 2024-10-25 Andrei Manolache , Dragos Tantaru , Mathias Niepert

The idea that complex systems have a hierarchical modular organization originates in the early 1960s and has recently attracted fresh support from quantitative studies of large scale, real-life networks. Here we investigate the hierarchical…

Data Analysis, Statistics and Probability · Physics 2010-04-20 D. Meunier , R. Lambiotte , A. Fornito , K. D. Ersche , E. T. Bullmore

Unified models aim to support both understanding and generation by encoding images into discrete tokens and processing them alongside text within a single autoregressive framework. This unified design offers architectural simplicity and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ziyao Wang , Chen Chen , Jingtao Li , Weiming Zhuang , Jiabo Huang , Ang Li , Lingjuan Lyu

Deciphering brain function through non-invasive recordings requires synthesizing complementary high-frequency electromagnetic (EEG/MEG) and low-frequency metabolic (fMRI) signals. However, despite their shared neural origins, extreme…

Neurons and Cognition · Quantitative Biology 2026-02-26 Changli Tang , Shurui Li , Junliang Wang , Qinfan Xiao , Zhonghao Zhai , Lei Bai , Yu Qiao , Bowen Zhou , Wen Wu , Yuanning Li , Chao Zhang

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

Neurons and Cognition · Quantitative Biology 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Recent advancements in the acquisition of various brain data sources have created new opportunities for integrating multimodal brain data to assist in early detection of complex brain disorders. However, current data integration approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Reza Shirkavand , Liang Zhan , Heng Huang , Li Shen , Paul M. Thompson

Understanding how the brain's complex nonlinear dynamics give rise to cognitive function remains a central challenge in neuroscience. While brain functional dynamics exhibits scale-free and multifractal properties across temporal scales,…

Neurons and Cognition · Quantitative Biology 2025-06-18 Sangyoon Bae , Junbeom Kwon , Shinjae Yoo , Jiook Cha

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

The work proposes a novel deep-learning framework for the synthesis of three-dimensional MRI volumes from corresponding 3D ultrasound images of the brain, leveraging a modified iteration of the Pix2Pix Generative Adversarial Network (GAN)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Shubham Singh , Mrunal Bewoor , Ammar Ranapurwala , Satyam Rai , Sheetal Patil

Brain network analysis provides an interpretable framework for characterizing brain organization and has been widely used for neurological disorder identification. Recent advances in self-supervised learning have motivated the development…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jiaxing Xu , Jingying Ma , Xin Lin , Yuxiao Liu , Kai He , Qika Lin , Yiping Ke , Yang Li , Dinggang Shen , Mengling Feng