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DNA methylation (DNAme) is a critical component of the epigenetic regulatory machinery and aberrations in DNAme patterns occur in many diseases, such as cancer. Mapping and understanding DNAme profiles offers considerable promise for…
Phase microscopy is an invaluable tool in the biosciences and in clinical diagnostics. The sensitivity of current phase microscopy techniques is optimized for one specific mean phase value and varies significantly across a given sample.…
Three-dimensional (3D) printing of bioelectronics offers a versatile platform for fabricating personalized and structurally integrated electronic systems within biological scaffolds. Biodegradable electronics, which naturally dissolve after…
Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel…
Contactless fingerprint recognition offers a higher level of user comfort and addresses hygiene concerns more effectively. However, it is also more vulnerable to presentation attacks such as photo paper, paper-printout, and various display…
Measuring gene expression simultaneously in both hosts and symbionts offers a powerful approach to explore the biology underlying species interactions. Such dual or simultaneous RNAseq approaches have primarily been used to gain insight…
Simulating in silico cellular responses to interventions is a promising direction to accelerate high-content image-based assays, critical for advancing drug discovery and gene editing. To support this, we introduce MorphGen, a…
In this letter, we propose a dielectric-modulated Impact-Ionization MOS (DIMOS) transistor based sensor for application in label-free detection of biomolecules. Numerous reports exist on the experimental demonstration of nanogap-embedded…
As spatial and temporal resolutions of scientific instruments improve, the explosion in the volume of data produced is becoming a key challenge. It can be a critical bottleneck for integration between scientific instruments at the edge and…
Clinical biosensors with low detection limit hold significant promise in the early diagnosis of debilitating diseases. Recent progress in sensor development has led to the demonstration of detection capable of detecting target molecules…
Optical biosensors based on micro-/nano-fibers are highly valuable for probing and monitoring liquid environments and bioactivity. Most of current optical biosensors, however, are still based on glass, semiconductors, or metallic materials,…
Machine learning sensors represent a paradigm shift for the future of embedded machine learning applications. Current instantiations of embedded machine learning (ML) suffer from complex integration, lack of modularity, and privacy and…
A maskless post-processing technique for CMOS chips is developed that enables the fabrication of RF MEMS parallel-plate capacitors with a high quality factor and a very compact size. Simulations and measured results are presented for…
The continuous growth in data volume has sparked interest in silicon-organic-hybrid nanophotonic devices integrated into silicon photonic integrated circuits (PICs). SOH devices offer improved speed and energy efficiency compared to silicon…
Parallel acquisition systems arise in various applications in order to moderate problems caused by insufficient measurements in single-sensor systems. These systems allow simultaneous data acquisition in multiple sensors, thus alleviating…
Most of the existing bi-modal (RGB-D and RGB-T) salient object detection methods utilize the convolution operation and construct complex interweave fusion structures to achieve cross-modal information integration. The inherent local…
For the Inner Tracking System 3 (ITS3) upgrade, the ALICE experiment at CERN requires monolithic active pixel sensors of dimensions up to 97~mm$\,\times\,$266~mm, occupying a large fraction of a 300 mm wafer. To manufacture such a…
Integrated micro-nanochannel networks in fluidic devices are desirable in a number of applications ranging from self-healing/cooling materials to bioengineering. The conventional micro-manufacturing techniques are capable of either…
Quantum sensing has drawn considerable attention as a means to overcome the fundamental limitations in classical sensing. In practice, however, quantum sensing has been strongly constrained by the photon loss, the achievable photon number N…
Size and shape are critical discriminators between molecular species and states. We describe a micro-chip based high-throughput imaging approach offering rapid and precise determination of molecular properties under native solution…