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We describe an instrument which can be used to analyze complex chemical mixtures at high resolution and high sensitivity. Molecules are collisionally cooled with helium gas at cryogenic temperatures (~ 4-7 K), and subsequently detected…

Instrumentation and Detectors · Physics 2019-05-22 Jessica P. Porterfield , Lincoln Satterthwaite , Sandra Eibenberger , David Patterson , Michael C. McCarthy

The integration of biological principles into artificial olfactory systems has led to significant advancements in odor detection and classification. Inspired by the intricate mechanisms of natural olfaction, researchers are developing…

Neurons and Cognition · Quantitative Biology 2025-02-13 Ravirajan K , Arvind Sundararajan

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

Monolithic active pixel sensors (MAPS) produced in a 65 nm CMOS imaging technology are being investigated for applications in particle physics. The MAPS design has a small collection electrode characterized by an input capacitance of ~fF,…

There is a widely-accepted need to revise current forms of health-care provision, with particular interest in sensing systems in the home. Given a multiple-modality sensor platform with heterogeneous network connectivity, as is under…

Machine Learning · Statistics 2017-02-07 Tom Diethe , Niall Twomey , Meelis Kull , Peter Flach , Ian Craddock

Missing modalities remain a major challenge for multimodal sensing, because most existing methods adapt the fusion process to the observed subset by dropping absent branches, using subset-specific fusion, or reconstructing missing features.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Hao Wang , Yanyu Qian , Pengcheng Weng , Zixuan Xia , William Dan , Yangxin Xu , Fei Wang

Recent advances in high-throughput sequencing technologies have enabled the extraction of multiple features that depict patient samples at diverse and complementary molecular levels. The generation of such data has led to new challenges in…

Genomics · Quantitative Biology 2022-09-14 Hakim Benkirane , Yoann Pradat , Stefan Michiels , Paul-Henry Cournède

One of the most important processes in the fight against current and future pandemics is the rapid diagnosis and initiation of treatment of viruses in humans. In these times, the development of high-sensitivity tests and diagnostic kits is…

Optics · Physics 2022-12-13 Junfei Wang , Zhenyu Xu , Domna G. Kotsifaki

Over the last few decades, modern industrial processes have investigated several cost-effective methodologies to improve the productivity and yield of semiconductor manufacturing. While playing an essential role in facilitating real-time…

Machine Learning · Computer Science 2021-11-16 Jaswanth Yella , Chao Zhang , Sergei Petrov , Yu Huang , Xiaoye Qian , Ali A. Minai , Sthitie Bom

We present a new technique for obtaining simultaneous multimodal quantitative phase and fluorescence microscopy of biological cells, providing both quantitative phase imaging and molecular specificity using a single camera. Our system is…

Optics · Physics 2019-04-03 Yoav N. Nygate , Gyanendra Singh , Itay Barnea , Natan T. Shaked

A quantum wavemetry scheme based on the coherence de Broglie wavelength (CBW) is proposed using an M coupled Mach Zehnder interferometer (MZI) architecture to achieve superresolution sensing and metrology. Although CBW does not attain the…

Quantum Physics · Physics 2026-03-09 B. S. Ham

A fundamental issue in biomedical and environmental sciences is the development of sensitive and robust sensors able to probe the analyte of interest, under physiological and pathological conditions or in environmental samples, and with…

Materials Science · Physics 2015-11-10 Loretta L. del Mercato , Maria Moffa , Rosaria Rinaldi , Dario Pisignano

Pixel sensors using 8" CMOS processing technology have been designed and characterized offering the benefits of industrial sensor fabrication, including large wafers, high throughput and yield, as well as low cost. The pixel sensors are…

Instrumentation and Detectors · Physics 2017-08-02 D. -L. Pohl , T. Hemperek , I. Caicedo , L. Gonella , F. Hügging , J. Janssen , H. Krüger , A. Macchiolo , N. Owtscharenko , L. Vigani , N. Wermes

Performant on-chip spectrometers are important for advancing sensing technologies, from environmental monitoring to biomedical diagnostics. As device footprints approach the scale of the operating wavelength, previously strategies,…

Multimodal approaches that integrate histology and genomics hold strong potential for precision oncology. However, phenotypic and genotypic heterogeneity limits the quality of intra-modal representations and hinders effective inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Yupei Zhang , Yating Huang , Wanming Hu , Lequan Yu , Hujun Yin , Chao Li

In spite of the benefits of biometric-based authentication systems, there are few concerns raised because of the sensitivity of biometric data to outliers, low performance caused due to intra-class variations and privacy invasion caused by…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Rudresh Dwivedi , Somnath Dey

This paper proposes a novel wireless, battery-free, and label-free biosensor for minimally invasive and non-invasive permittivity sensing for applications such as detecting glucose levels in the interstitial dermal fluid. The miniaturized,…

Applied Physics · Physics 2022-10-19 Rehab S. Hassan

Optically addressable spin-based quantum sensors enable nanoscale measurements of temperature, magnetic field, pH, and other physical properties of a system. Advancing the sensors beyond proof-of-principle demonstrations in living cells and…

We report on the development of commercially fabricated multi-chroic antenna coupled Transition Edge Sensor (TES) bolometer arrays for Cosmic Microwave Background (CMB) polarimetry experiments. CMB polarimetry experiments have deployed…

Instrumentation and Methods for Astrophysics · Physics 2018-05-09 Aritoki Suzuki , Chris Bebek , Maurice Garcia-Sciveres , Stephen Holland , Akito Kusaka , Adrian T. Lee , Nicholas Palaio , Natalie Roe , Leo Steinmetz

We design and demonstrate a monolithically integrated silicon photonic multichannel optical hybrid for versatile broadband coherent reception, addressing the critical limitations of current wavelength multiplexed systems in scalability and…