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In many settings, interventions may be more effective for some individuals than others, so that targeting interventions may be beneficial. We analyze the value of targeting in the context of a large-scale field experiment with over 53,000…

Econometrics · Economics 2024-06-04 Susan Athey , Niall Keleher , Jann Spiess

Qatar has undergone distinct waves of COVID-19 infections, compounded by the emergence of variants, posing additional complexities. This research uniquely delves into the varied efficacy of existing vaccines and the pivotal role of…

Applications · Statistics 2023-12-29 Elizabeth Amona , Indranil Sahoo , Edward Boone , Ryad Ghanam

This paper investigates the effects of vaccination on the dynamics of infectious disease, which is spreading in a population concurrently with awareness. The model considers contributions to the overall awareness from a global information…

Quantitative Methods · Quantitative Biology 2018-05-14 G. O. Agaba , Y. N. Kyrychko , K. B. Blyuss

Often, vaccination programs are carried out based on self-interest rather than being mandatory. Owing to the perceptions about risks associated with vaccines and the `herd immunity' effect, it may provide suboptimal vaccination coverage for…

Physics and Society · Physics 2012-07-20 Hai-Feng Zhang , Zhi-Xi Wu , Xiao-Ke Xu , Michael Small , Bing-Hong Wang

Background: By the beginning of December 2020, some vaccines against COVID-19 already presented efficacy and security, which qualify them to be used in mass vaccination campaigns. Thus, setting up strategies of vaccination became crucial to…

Populations and Evolution · Quantitative Biology 2021-02-25 Vinicius V. L. Albani , Jennifer Loria , Eduardo Massad , Jorge P. Zubelli

Factorial experiments are ubiquitous in the social and biomedical sciences, but when units fail to comply with each assigned factors, identification and estimation of the average treatment effects become impossible without strong…

Methodology · Statistics 2025-08-06 Matthew Blackwell , Nicole E. Pashley

Effective vaccine prioritization is critical for epidemic control, yet real outbreaks exhibit memory effects that inflate state space and make long-term prediction and optimization challenging. As a result, many strategies are tuned to…

Biological Physics · Physics 2025-11-11 Mi Feng , Liang Tian , Changsong Zhou

Covid-19 vaccination has posed crucial challenges to policymakers and health administrations worldwide. In addition to the pressure posed by the pandemic, government administration has to strive against vaccine hesitancy, which seems to be…

Applications · Statistics 2022-03-29 Giulio Grossi

COVID-19 vaccines have proven to be effective against SARS-CoV-2 infection. However, the dynamics of vaccine-induced immunological memory development and neutralizing antibodies generation are not fully understood, limiting vaccine…

Quantitative Methods · Quantitative Biology 2022-04-06 Xin Gao , Jianwei Li , Dianjie Li

Recent approaches to real-time long video generation typically employ streaming tuning strategies, attempting to train a long-context student using a short-context (memoryless) teacher. In these frameworks, the student performs long…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Shuo Chen , Cong Wei , Sun Sun , Ping Nie , Kai Zhou , Ge Zhang , Ming-Hsuan Yang , Wenhu Chen

The proximal causal inference framework enables the identification and estimation of causal effects in the presence of unmeasured confounding by leveraging two disjoint sets of observed strong proxies: negative control treatments and…

Methodology · Statistics 2025-12-16 Antonio Olivas-Martinez , Peter B. Gilbert , Andrea Rotnitzky

Modern longitudinal studies collect feature data at many timepoints, often of the same order of sample size. Such studies are typically affected by {dropout} and positivity violations. We tackle these problems by generalizing effects of…

Methodology · Statistics 2022-03-16 Kwangho Kim , Edward H. Kennedy , Ashley I. Naimi

Background: Phase I trials desire to identify the maximum tolerated dose (MTD) early and proceed quickly to an expansion cohort or phase II trial for efficacy. We propose an early completion method based on multiple dosages to accelerate…

Quantitative Methods · Quantitative Biology 2021-10-04 Masahiro Kojima

In controlling transmission of COVID-19, the effectiveness of border quarantine strategies is a key concern for jurisdictions in which the local prevalence of disease and immunity is low. In settings like this such as China, Australia, and…

Populations and Evolution · Quantitative Biology 2021-09-28 Cameron Zachreson , Freya M. Shearer , David J. Price , Michael J. Lydeamore , Jodie McVernon , James McCaw , Nicholas Geard

By the end of 2020, a year since the first cases of infection by the Covid-19 virus have been reported, there is a light at the end of the tunnel. Several pharmaceutical companies made significant progress in developing effective vaccines…

Populations and Evolution · Quantitative Biology 2021-08-04 Hilla De-Leon , Francesco Pederiva

We explore the causal relationship between COVID-19 lockdown policies and changes in personal computer usage. In particular, we examine how lockdown policies affected average daily computer usage, as well as how it affected usage patterns…

Applications · Statistics 2025-03-14 Mingjia Zhu , Lechuan Wang , Julien Sebot , Bijan Arbab , Babak Salimi , Alexander Cloninger

Mass vaccination remains a long-lasting challenge for disease control and prevention with upticks in vaccine hesitancy worldwide. Here, we introduce an experience-based learning (Q-learning) dynamics model of vaccination behavior in social…

Physics and Society · Physics 2025-11-03 Atticus McWhorter , Feng Fu

Considering the global pandemic of coronavirus disease 2019 (COVID-19), around the world several vaccines are being developed. Till now, these vaccines are the most effective way to reduce the high burden on the global health…

Physics and Society · Physics 2023-02-22 Dibyajyoti Mallick , Aniruddha Ray , Ankita Das , Sayantari Ghosh

A reinforcement learning agent that needs to pursue different goals across episodes requires a goal-conditional policy. In addition to their potential to generalize desirable behavior to unseen goals, such policies may also enable…

Machine Learning · Computer Science 2019-02-21 Paulo Rauber , Avinash Ummadisingu , Filipe Mutz , Juergen Schmidhuber

This study aims to statistically assess the effectiveness of vaccination against SARS-CoV-2. It is indispensable to investigate the relationship between Covid-19 deadliness and vaccination in order to study the impact of vaccine in…

Quantitative Methods · Quantitative Biology 2022-02-04 MD. Rayhan , M. Abdullah-Al-Wadud , M. Helal Uddin Ahmed