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Related papers: Clinical Uncertainty Impacts Machine Learning Eval…

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This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

Many important computer vision applications are naturally formulated as regression problems. Within medical imaging, accurate regression models have the potential to automate various tasks, helping to lower costs and improve patient…

Machine Learning · Computer Science 2023-11-08 Fredrik K. Gustafsson , Martin Danelljan , Thomas B. Schön

Quantifying aleatoric uncertainty in medical image segmentation is critical since it is a reflection of the natural variability observed among expert annotators. A conventional approach is to model the segmentation distribution using the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Phi Van Nguyen , Ngoc Huynh Trinh , Duy Minh Lam Nguyen , Phu Loc Nguyen , Quoc Long Tran

Measuring uncertainties in the output of a deep learning method is useful in several ways, such as in assisting with interpretation of the outputs, helping build confidence with end users, and for improving the training and performance of…

Machine Learning · Computer Science 2022-09-20 Luke Whitbread , Mark Jenkinson

Uncertainty quantification is a key pillar of trustworthy machine learning. It enables safe reactions under unsafe inputs, like predicting only when the machine learning model detects sufficient evidence, discarding anomalous data, or…

Machine Learning · Computer Science 2024-08-27 Michael Kirchhof

Many operational AI systems depend on large-scale human annotation to detect rare but consequential events (e.g., fraud, defects, and medical abnormalities). When positives are rare, the prevalence effect induces systematic cognitive biases…

Human-Computer Interaction · Computer Science 2026-03-13 Gunnar P. Epping , Andrew Caplin , Erik Duhaime , William R. Holmes , Daniel Martin , Jennifer S. Trueblood

Supervised classification heavily depends on datasets annotated by humans. However, in subjective tasks such as toxicity classification, these annotations often exhibit low agreement among raters. Annotations have commonly been aggregated…

Computation and Language · Computer Science 2024-05-17 Negar Mokhberian , Myrl G. Marmarelis , Frederic R. Hopp , Valerio Basile , Fred Morstatter , Kristina Lerman

Medical imaging classifiers can achieve high predictive accuracy, but quantifying their uncertainty remains an unresolved challenge, which prevents their deployment in medical clinics. We present an algorithm that can modify any classifier…

Machine Learning · Computer Science 2024-08-12 Roy Hirsch , Jacob Goldberger

Researchers have raised awareness about the harms of aggregating labels especially in subjective tasks that naturally contain disagreements among human annotators. In this work we show that models that are only provided aggregated labels…

Computation and Language · Computer Science 2024-03-08 Abhishek Anand , Negar Mokhberian , Prathyusha Naresh Kumar , Anweasha Saha , Zihao He , Ashwin Rao , Fred Morstatter , Kristina Lerman

As a means of human-based computation, crowdsourcing has been widely used to annotate large-scale unlabeled datasets. One of the obvious challenges is how to aggregate these possibly noisy labels provided by a set of heterogeneous…

Machine Learning · Computer Science 2020-10-20 Xuan Wei , Daniel Dajun Zeng , Junming Yin

Rigorous statistical methods, including parameter estimation with accompanying uncertainties, underpin the validity of scientific discovery, especially in the natural sciences. With increasingly complex data models such as deep learning…

Machine Learning · Computer Science 2026-02-18 Aurora Grefsrud , Nello Blaser , Trygve Buanes

Probably yes. -- Supervised Deep Learning dominates performance scores for many computer vision tasks and defines the state-of-the-art. However, medical image analysis lags behind natural image applications. One of the many reasons is the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-02 Samuel Budd , Thomas Day , John Simpson , Karen Lloyd , Jacqueline Matthew , Emily Skelton , Reza Razavi , Bernhard Kainz

Datasets labelled by human annotators are widely used in the training and testing of machine learning models. In recent years, researchers are increasingly paying attention to label quality. However, it is not always possible to objectively…

Computer Vision and Pattern Recognition · Computer Science 2024-05-15 Luisa Schwirten , Jannes Scholz , Daniel Kondermann , Janis Keuper

Current medical language model (LM) benchmarks often over-simplify the complexities of day-to-day clinical practice tasks and instead rely on evaluating LMs on multiple-choice board exam questions. In psychiatry especially, these challenges…

Current deep learning paradigms largely benefit from the tremendous amount of annotated data. However, the quality of the annotations often varies among labelers. Multi-observer studies have been conducted to study these annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Xiaosong Wang , Ziyue Xu , Dong Yang , Leo Tam , Holger Roth , Daguang Xu

Algorithms and technologies are essential tools that pervade all aspects of our daily lives. In the last decades, health care research benefited from new computer-based recruiting methods, the use of federated architectures for data…

Computers and Society · Computer Science 2023-01-26 Chiara Criscuolo , Tommaso Dolci , Mattia Salnitri

Aleatoric uncertainty quantification seeks for distributional knowledge of random responses, which is important for reliability analysis and robustness improvement in machine learning applications. Previous research on aleatoric uncertainty…

Machine Learning · Computer Science 2022-06-10 Ziyi Huang , Henry Lam , Haofeng Zhang

Majority voting and averaging are common approaches employed to resolve annotator disagreements and derive single ground truth labels from multiple annotations. However, annotators may systematically disagree with one another, often…

Computation and Language · Computer Science 2021-10-13 Aida Mostafazadeh Davani , Mark Díaz , Vinodkumar Prabhakaran

When constructing models that learn from noisy labels produced by multiple annotators, it is important to accurately estimate the reliability of annotators. Annotators may provide labels of inconsistent quality due to their varying…

Computation and Language · Computer Science 2019-05-14 Maolin Li , Arvid Fahlström Myrman , Tingting Mu , Sophia Ananiadou

Uncertainty in machine learning models is a timely and vast field of research. In supervised learning, uncertainty can already occur in the first stage of the training process, the annotation phase. This scenario is particularly evident…

Machine Learning · Computer Science 2024-07-24 Katharina Hechinger , Christoph Koller , Xiao Xiang Zhu , Göran Kauermann