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Predicting protein secondary structure is a fundamental problem in protein structure prediction. Here we present a new supervised generative stochastic network (GSN) based method to predict local secondary structure with deep hierarchical…

Quantitative Methods · Quantitative Biology 2014-03-07 Jian Zhou , Olga G. Troyanskaya

Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Siyuan Yan , Chi Liu , Zhen Yu , Lie Ju , Dwarikanath Mahapatra , Brigid Betz-Stablein , Victoria Mar , Monika Janda , Peter Soyer , Zongyuan Ge

With the incredible results achieved from generative pre-trained transformers (GPT) and diffusion models, generative AI (GenAI) is envisioned to yield remarkable breakthroughs in various industrial and academic domains. In this paper, we…

Information Theory · Computer Science 2023-09-19 Mehdi Letafati , Samad Ali , Matti Latva-aho

Spatial transcriptomics offers spatially resolved gene expression profiling within tissue sections, but its cost and limited throughput hinder large-scale deployment. To extend this capability to routine practice, recent computational…

Machine Learning · Computer Science 2026-05-07 Keunho Byeon , Jin Tae Kwak

Unsupervised Contrastive learning has gained prominence in fields such as vision, and biology, leveraging predefined positive/negative samples for representation learning. Data augmentation, categorized into hand-designed and model-based…

Machine Learning · Computer Science 2024-05-28 Zelin Zang , Hao Luo , Kai Wang , Panpan Zhang , Fan Wang , Stan. Z Li , Yang You

Data based materials science is the new promise to accelerate materials design. Especially in computational materials science, data generation can easily be automatized. Usually, the focus is on processing and evaluating the data to derive…

Materials Science · Physics 2022-04-28 Martin Kroll , Timo Schmalofski , Holger Dette , Rebecca Janisch

Animals are known to make efficient probabilistic inferences based on uncertain and noisy information from the outside world. Although it is known that generic neural networks can perform near-optimal point estimation by probabilistic…

Neurons and Cognition · Quantitative Biology 2021-11-10 Kohei Ichikawa , Asaki Kataoka

An important goal of medical imaging is to be able to precisely detect patterns of disease specific to individual scans; however, this is challenged in brain imaging by the degree of heterogeneity of shape and appearance. Traditional…

Automatic font generation without human experts is a practical and significant problem, especially for some languages that consist of a large number of characters. Existing methods for font generation are often in supervised learning. They…

Computer Vision and Pattern Recognition · Computer Science 2023-01-02 Xinyuan Chen , Yangchen Xie , Li Sun , Yue Lu

Diffusion Models (DMs) have emerged as powerful generative models with unprecedented image generation capability. These models are widely used for data augmentation and creative applications. However, DMs reflect the biases present in the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-11 Rishubh Parihar , Abhijnya Bhat , Abhipsa Basu , Saswat Mallick , Jogendra Nath Kundu , R. Venkatesh Babu

Symbolic regression (SR) models complex systems by discovering mathematical expressions that capture underlying relationships in observed data. However, most SR methods prioritize minimizing prediction error over identifying the governing…

Machine Learning · Computer Science 2026-03-31 Giorgio Morales , John W. Sheppard

Semantic GP is a promising approach that introduces semantic awareness during genetic evolution. This paper presents a new Semantic GP approach based on Dynamic Target (SGP-DT) that divides the search problem into multiple GP runs. The…

Neural and Evolutionary Computing · Computer Science 2020-02-03 Stefano Ruberto , Valerio Terragni , Jason H. Moore

Developing mathematical models of dynamic systems is central to many disciplines of engineering and science. Models facilitate simulations, analysis of the system's behavior, decision making and design of automatic control algorithms. Even…

Machine Learning · Computer Science 2020-06-19 Erik Derner , Jiří Kubalík , Nicola Ancona , Robert Babuška

Domain-general semantic parsing is a long-standing goal in natural language processing, where the semantic parser is capable of robustly parsing sentences from domains outside of which it was trained. Current approaches largely rely on…

Computation and Language · Computer Science 2022-02-10 Abulhair Saparov

We investigate the addition of constraints on the function image and its derivatives for the incorporation of prior knowledge in symbolic regression. The approach is called shape-constrained symbolic regression and allows us to enforce e.g.…

Neural and Evolutionary Computing · Computer Science 2021-06-01 Gabriel Kronberger , Fabricio Olivetti de França , Bogdan Burlacu , Christian Haider , Michael Kommenda

Symbolic regression that aims to detect underlying data-driven models has become increasingly important for industrial data analysis. For most existing algorithms such as genetic programming (GP), the convergence speed might be too slow for…

Neural and Evolutionary Computing · Computer Science 2017-10-31 Chen Chen , Changtong Luo , Zonglin Jiang

Domain adaptive semantic segmentation aims to generate accurate and dense predictions for an unlabeled target domain by leveraging a supervised model trained on a labeled source domain. The prevalent self-training approach involves…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Nazanin Moradinasab , Laura S. Shankman , Rebecca A. Deaton , Gary K. Owens , Donald E. Brown

Unsupervised Domain Adaptation (UDA) aims to align source and target domain distributions to close the domain gap, but still struggles with obtaining the target data. Fortunately, Domain Generalization (DG) excels without the need for any…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Binbin Wei , Yuhang Zhang , Shishun Tian , Muxin Liao , Wei Li , Wenbin Zou

Single domain generalization (SDG) aims to train a robust model against unknown target domain shifts using data from a single source domain. Data augmentation has been proven an effective approach to SDG. However, the utility of standard…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Guangtao Zheng , Mengdi Huai , Aidong Zhang

Symbolic regression, as one of the most crucial tasks in AI for science, discovers governing equations from experimental data. Popular approaches based on genetic programming, Monte Carlo tree search, or deep reinforcement learning learn…

Neural and Evolutionary Computing · Computer Science 2023-09-18 Nan Jiang , Yexiang Xue
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