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Spatial transcriptomics enables gene expression profiling with spatial context, offering unprecedented insights into the tissue microenvironment. However, most computational models treat genes as isolated numerical features, ignoring the…

Machine Learning · Computer Science 2025-11-17 Jiangkai Long , Yanran Zhu , Chang Tang , Kun Sun , Yuanyuan Liu , Xuesong Yan

Genetic programming is an often-used technique for symbolic regression: finding symbolic expressions that match data from an unknown function. To make the symbolic regression more efficient, one can also use dimensionally-aware genetic…

Neural and Evolutionary Computing · Computer Science 2020-04-28 Marko Durasevic , Domagoj Jakobovic , Marcella Scoczynski Ribeiro Martins , Stjepan Picek , Markus Wagner

We develop a symbolic regression framework for extracting the governing mathematical expressions from observed data. The evolutionary approach, faiGP, is designed to leverage the properties of a function algebra that have been encoded into…

Neural and Evolutionary Computing · Computer Science 2022-03-18 Shahab Razavi , Eric R. Gamazon

We introduce a data-driven framework to automatically identify interpretable and physically meaningful hyperelastic constitutive models from sparse data. Leveraging symbolic regression, an algorithm based on genetic programming, our…

Symbolic Computation · Computer Science 2025-01-14 Jixin Hou , Xianyan Chen , Taotao Wu , Ellen Kuhl , Xianqiao Wang

Genetic programming has been widely used in the engineering field. Compared with the conventional genetic programming and artificial neural network, geometric semantic genetic programming (GSGP) is superior in astringency and computing…

Neural and Evolutionary Computing · Computer Science 2017-12-06 Juncai Xu , Zhenzhong Shen , Qingwen Ren , Xin Xie , Zhengyu Yang

The pretraining-finetuning paradigm is a crucial strategy in metallic surface defect detection for mitigating the challenges posed by data scarcity. However, its implementation presents a critical dilemma. Pretraining on natural image…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Chuni Liu , Hongjie Li , Jiaqi Du , Yangyang Hou , Qian Sun , Lei Jin , Ke Xu

Data-driven constitutive modeling is an emerging field in computational solid mechanics with the prospect of significantly relieving the computational costs of hierarchical computational methods. Traditionally, these surrogates have been…

Computational Engineering, Finance, and Science · Computer Science 2022-04-20 Jan Niklas Fuhg , Nikolaos Bouklas

Growing interest in modelling complex systems from brains to societies to cities using networks has led to increased efforts to describe generative processes that explain those networks. Recent successes in machine learning have prompted…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Govind Gandhi

In this paper, a nonlinear symbolic regression technique using an evolutionary algorithm known as multi-gene genetic programming (MGGP) is applied for a data-driven modelling between the dependent and the independent variables. The…

Neural and Evolutionary Computing · Computer Science 2014-03-05 Indranil Pan , Daya Shankar Pandey , Saptarshi Das

Symbolic regression is a powerful system identification technique in industrial scenarios where no prior knowledge on model structure is available. Such scenarios often require specific model properties such as interpretability, robustness,…

This paper presents a Domain-Inspired Sharpness-Aware Minimization (DISAM) algorithm for optimization under domain shifts. It is motivated by the inconsistent convergence degree of SAM across different domains, which induces optimization…

Computer Vision and Pattern Recognition · Computer Science 2024-05-30 Ruipeng Zhang , Ziqing Fan , Jiangchao Yao , Ya Zhang , Yanfeng Wang

Domain Generalized Semantic Segmentation (DGSS) is a critical yet challenging task, as domain shifts in unseen environments can severely compromise model performance. While recent studies enhance feature alignment by projecting features…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 I-Hsiang Chen , Hua-En Chang , Wei-Ting Chen , Jenq-Neng Hwang , Sy-Yen Kuo

The Diffusion Probabilistic Model (DPM) has emerged as a highly effective generative model in the field of computer vision. Its intermediate latent vectors offer rich semantic information, making it an attractive option for various…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Haipeng Zhou , Lei Zhu , Yuyin Zhou

Domain Generalization (DG) is a critical area that focuses on developing models capable of performing well on data from unseen distributions, which is essential for real-world applications. Existing approaches primarily concentrate on…

Machine Learning · Computer Science 2026-01-28 Xudong Han , Senkang Hu , Yihang Tao , Yu Guo , Philip Birch , Sam Tak Wu Kwong , Yuguang Fang

With recent advancements in non-invasive techniques for measuring brain activity, such as magnetic resonance imaging (MRI), the study of structural and functional brain networks through graph signal processing (GSP) has gained notable…

Machine Learning · Computer Science 2025-11-13 Martín Schmidt , Sara Silva , Federico Larroca , Gonzalo Mateos , Pablo Musé

Discrete diffusion models generate sequences by iteratively denoising samples corrupted by categorical noise, offering an appealing alternative to autoregressive decoding for structured and symbolic generation. However, standard training…

Machine Learning · Computer Science 2026-02-04 Huu Binh Ta , Michael Cardei , Alvaro Velasquez , Ferdinando Fioretto

Black box deep learning models trained on genomic sequences excel at predicting the outcomes of different gene regulatory mechanisms. Therefore, interpreting these models may provide novel insights into the underlying biology, supporting…

Machine Learning · Computer Science 2024-07-18 Pedro Barbosa , Rosina Savisaar , Alcides Fonseca

Genetic variation in human populations is influenced by geographic ancestry due to spatial locality in historical mating and migration patterns. Spatial population structure in genetic datasets has been traditionally analyzed using either…

Populations and Evolution · Quantitative Biology 2016-10-26 Anand Bhaskar , Adel Javanmard , Thomas A. Courtade , David Tse

Repetitive DNA (repeats) poses significant challenges for accurate and efficient genome assembly and sequence alignment. This is particularly true for metagenomic data, where genome dynamics such as horizontal gene transfer, gene…

Machine Learning · Computer Science 2024-02-15 Ali Azizpour , Advait Balaji , Todd J. Treangen , Santiago Segarra

Most of the dynamic graph representation learning methods involve dividing a dynamic graph into discrete snapshots to capture the evolving behavior of nodes over time. Existing methods primarily capture only local or global structures of…

Machine Learning · Computer Science 2025-12-23 Bizhan Alipour Pijan , Serdar Bozdag