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Embedding algorithms are increasingly used to represent clinical concepts in healthcare for improving machine learning tasks such as clinical phenotyping and disease prediction. Recent studies have adapted state-of-the-art bidirectional…

Machine Learning · Computer Science 2021-12-07 Chao Pang , Xinzhuo Jiang , Krishna S Kalluri , Matthew Spotnitz , RuiJun Chen , Adler Perotte , Karthik Natarajan

Foundation models have demonstrated remarkable generalization, data efficiency, and robustness properties across various domains. In this paper, we explore the feasibility of foundation models for applications in the control domain. The…

Machine Learning · Computer Science 2024-12-18 Martin Ziegler , Andres Felipe Posada-Moreno , Friedrich Solowjow , Sebastian Trimpe

Motor condition monitoring is essential for ensuring system reliability and preventing catastrophic failures. However, data-driven diagnostic methods often suffer from sparse fault labels and severe class imbalance, which limit their…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Deyu Li , Xinyuan Liao , Shaowei Chen , Shuai Zhao

Graphs are a central representation in biomedical research, capturing molecular interaction networks, gene regulatory circuits, cell--cell communication maps, and knowledge graphs. Despite their importance, currently there is not a broadly…

Machine Learning · Computer Science 2026-04-09 Sakib Mostafa , Lei Xing , Md. Tauhidul Islam

The growing demand for accurate and equitable AI models in digital dermatology faces a significant challenge: the lack of diverse, high-quality labeled data. In this work, we investigate the potential of domain-specific foundation models…

Modeling temporal changes in subcortical structures is crucial for a better understanding of the progression of Alzheimer's disease (AD). Given their flexibility to adapt to heterogeneous sequence lengths, mesh-based transformer…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Ignacio Sarasua , Sebastian Pölsterl , Christian Wachinger

Recent advances in deep learning architectures for sequence modeling have not fully transferred to tasks handling time-series from electronic health records. In particular, in problems related to the Intensive Care Unit (ICU), the…

Machine Learning · Computer Science 2024-02-07 Rita Kuznetsova , Alizée Pace , Manuel Burger , Hugo Yèche , Gunnar Rätsch

Longitudinal data in electronic health records (EHRs) represent an individual`s clinical history through a sequence of codified concepts, including diagnoses, procedures, medications, and laboratory tests. Generative pre-trained…

In this work, we investigate unsupervised representation learning on medical time series, which bears the promise of leveraging copious amounts of existing unlabeled data in order to eventually assist clinical decision making. By evaluating…

Machine Learning · Computer Science 2018-12-04 Xinrui Lyu , Matthias Hueser , Stephanie L. Hyland , George Zerveas , Gunnar Raetsch

This article discusses the opportunities, applications and future directions of large-scale pre-trained models, i.e., foundation models, for analyzing medical images. Medical foundation models have immense potential in solving a wide range…

Image and Video Processing · Electrical Eng. & Systems 2023-11-23 Shaoting Zhang , Dimitris Metaxas

Foundation models refer to artificial intelligence (AI) models that are trained on massive amounts of data and demonstrate broad generalizability across various tasks with high accuracy. These models offer versatile, one-for-many or…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Rina Bao , Erfan Darzi , Sheng He , Chuan-Heng Hsiao , Mohammad Arafat Hussain , Jingpeng Li , Atle Bjornerud , Ellen Grant , Yangming Ou

Foundation models, particularly Large Language Models (LLMs), have revolutionized text and video processing, yet time series data presents distinct challenges for such approaches due to domain-specific features such as missing values,…

Machine Learning · Computer Science 2025-02-12 Defu Cao , Wen Ye , Yizhou Zhang , Yan Liu

Machine learning has revolutionized the modeling of clinical timeseries data. Using machine learning, a Deep Neural Network (DNN) can be automatically trained to learn a complex mapping of its input features for a desired task. This is…

Machine Learning · Computer Science 2024-10-15 Ryan King , Shivesh Kodali , Conrad Krueger , Tianbao Yang , Bobak J. Mortazavi

Deep learning models deployed in real-world applications (e.g., medicine) face challenges because source models do not generalize well to domain-shifted target data. Many successful domain adaptation (DA) approaches require full access to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Mainak Biswas , Ambedkar Dukkipati , Devarajan Sridharan

Existing foundation models (FMs) in the medical domain often require extensive fine-tuning or rely on training resource-intensive decoders, while many existing encoders are pretrained with objectives biased toward specific tasks. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Tim Veenboer , George Yiasemis , Eric Marcus , Vivien Van Veldhuizen , Cees G. M. Snoek , Jonas Teuwen , Kevin B. W. Groot Lipman

Electroencephalography (EEG) foundation models have shown strong potential for learning generalizable representations from large-scale neural data, yet their clinical deployment is hindered by distribution shifts across clinical settings,…

Machine Learning · Computer Science 2026-04-21 Gabriel Jason Lee , Jathurshan Pradeepkumar , Jimeng Sun

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to find meaningful temporal latent representations of an…

Clinical decision support tools built on electronic health records often experience performance drift due to temporal population shifts, particularly when changes in the clinical environment initially affect only a subset of patients,…

Machine Learning · Computer Science 2025-12-16 Mengying Yan , Ziye Tian , Siqi Li , Nan Liu , Benjamin A. Goldstein , Molei Liu , Chuan Hong

Randomized trials and observational studies, more often than not, run over a certain period of time. The treatment effect evolves during this period which provides crucial insights into the treatment response and the long-term effects. Many…

Methodology · Statistics 2020-04-13 Shu Li , Peter Bühlmann

In healthcare and biomedical applications, extreme computational requirements pose a significant barrier to adopting representation learning. Representation learning can enhance the performance of deep learning architectures by learning…

Machine Learning · Computer Science 2023-08-22 Pranav Singh , Jacopo Cirrone
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