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Counting and classifying blood cells is an important diagnostic tool in medicine. Support Vector Machines are increasingly popular and efficient and could replace artificial neural network systems. Here a method to classify blood cells is…

Applications · Statistics 2008-12-15 Tobias Abenius

Flow cytometry is a high-throughput technology used to quantify multiple surface and intracellular markers at the level of a single cell. This enables to identify cell sub-types, and to determine their relative proportions. Improvements of…

Machine Learning · Statistics 2022-11-10 Boris P. Hejblum , Chariff Alkhassim , Raphael Gottardo , François Caron , Rodolphe Thiébaut

Clustering algorithms have significantly improved along with Deep Neural Networks which provide effective representation of data. Existing methods are built upon deep autoencoder and self-training process that leverages the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2021-09-17 Xin Ma , Won Hwa Kim

An essential premise for neuroscience brain network analysis is the successful segmentation of the cerebral cortex into functionally homogeneous regions. Resting-state functional magnetic resonance imaging (rs-fMRI), capturing the…

Neurons and Cognition · Quantitative Biology 2023-09-20 Xiaoxiao Ma , Chunzhi Yi , Zhicai Zhong , Hui Zhou , Baichun Wei , Haiqi Zhu , Feng Jiang

The segmentation and classification of cardiac magnetic resonance imaging are critical for diagnosing heart conditions, yet current approaches face challenges in accuracy and generalizability. In this study, we aim to further advance the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Vitalii Slobodzian , Pavlo Radiuk , Oleksander Barmak , Iurii Krak

An innovative two-stage methodology for categorizing blood clot origins is presented in this paper, which is important for the diagnosis and treatment of ischemic stroke. First, a background classifier based on MobileNetV3 segments big…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Koushik Sivarama Krishnan , P. J. Joe Nikesh , Swathi Gnanasekar , Karthik Sivarama Krishnan

In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Shahira Abousamra , David Belinsky , John Van Arnam , Felicia Allard , Eric Yee , Rajarsi Gupta , Tahsin Kurc , Dimitris Samaras , Joel Saltz , Chao Chen

White blood cells (WBCs) play a crucial role in safeguarding the human body against pathogens and foreign substances. Leveraging the abundance of WBC imaging data and the power of deep learning algorithms, automated WBC analysis has the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-23 Aditya Shankar Pal , Debojyoti Biswas , Joy Mahapatra , Debasis Banerjee , Prantar Chakrabarti , Utpal Garain

Clustering is an essential technique for discovering patterns in data. The steady increase in amount and complexity of data over the years led to improvements and development of new clustering algorithms. However, algorithms that can…

Machine Learning · Statistics 2021-03-03 Shu Wang , Jonathan G. Yabes , Chung-Chou H. Chang

Inference in clustering is paramount to uncovering inherent group structure in data. Clustering methods which assess statistical significance have recently drawn attention owing to their importance for the identification of patterns in high…

Methodology · Statistics 2021-06-18 Debora Zava Bello , Marcio Valk , Gabriela Bettella Cybis

Detection and differentiation of circulating tumor cells (CTCs) and non-CTCs in blood draws of cancer patients pose multiple challenges. While the gold standard relies on tedious manual evaluation of an automatically generated selection of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Hümeyra Husseini-Wüsthoff , Sabine Riethdorf , Andreas Schneeweiss , Andreas Trumpp , Klaus Pantel , Harriet Wikman , Maximilian Nielsen , René Werner

In this paper, we present contemporary techniques for visualising the feature space of a deep learning image classification neural network. These techniques are viewed in the context of a feed-forward network trained to classify low…

Computer Vision and Pattern Recognition · Computer Science 2018-11-16 Ezra Webb , Cheng Lei , Chun-Jung Huang , Hirofumi Kobayashi , Hideharu Mikami , Keisuke Goda

Patch classification models based on deep learning have been utilized in whole-slide images (WSI) of H&E-stained tissue samples to assist pathologists in grading follicular lymphoma patients. However, these approaches still require…

Cluster analysis, or clustering, plays a crucial role across numerous scientific and engineering domains. Despite the wealth of clustering methods proposed over the past decades, each method is typically designed for specific scenarios and…

Methodology · Statistics 2026-01-22 Siyi Wang , Alexandre Leblanc , Paul D. McNicholas

As data sets continue to grow in size and complexity, effective and efficient techniques are needed to target important features in the variable space. Many of the variable selection techniques that are commonly used alongside clustering…

Computation · Statistics 2013-03-22 Jeffrey L. Andrews , Paul D. McNicholas

This work presents an unsupervised deep discriminant analysis for clustering. The method is based on deep neural networks and aims to minimize the intra-cluster discrepancy and maximize the inter-cluster discrepancy in an unsupervised…

Machine Learning · Computer Science 2022-06-13 Jinyu Cai , Wenzhong Guo , Jicong Fan

White blood cells, also known as leukocytes are group of heterogeneously nucleated cells which act as salient immune system cells. These are originated in the bone marrow and are found in blood, plasma, and lymph tissues. Leukocytes kill…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Shrijeet Biswas , Amartya Bhattacharya

In the current technological era, the medical profession has emerged as one of the researchers' favorite subject areas, and cancer is one of them. Because there is now no effective treatment for this illness, it is a matter of concern. Only…

Machine Learning · Computer Science 2024-10-23 Praneeth Kumar T , Nidhi Srivastava , Rakshith Mahishi , Chayadevi M L

We propose a deep learning clustering method that exploits dense features from a segmentation network for emphysema subtyping from computed tomography (CT) scans. Using dense features enables high-resolution visualization of image regions…

Image and Video Processing · Electrical Eng. & Systems 2021-06-03 Weiyi Xie , Colin Jacobs , Bram van Ginneken

Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

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