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Modeling the nonlinear dynamics of neuronal populations represents a key pursuit in computational neuroscience. Recent research has increasingly focused on jointly modeling neural activity and behavior to unravel their interconnections.…

Neural and Evolutionary Computing · Computer Science 2025-02-07 Zhengrui Guo , Fangxu Zhou , Wei Wu , Qichen Sun , Lishuang Feng , Jinzhuo Wang , Hao Chen

High-dimensional imaging of neural activity, such as widefield calcium and functional ultrasound imaging, provide a rich source of information for understanding the relationship between brain activity and behavior. Accurately modeling…

Neurons and Cognition · Quantitative Biology 2025-09-24 Mohammad Hosseini , Maryam M. Shanechi

Recurrent Neural Networks (RNNs) are popular models of brain function. The typical training strategy is to adjust their input-output behavior so that it matches that of the biological circuit of interest. Even though this strategy ensures…

Neurons and Cognition · Quantitative Biology 2020-11-09 Alessandro Salatiello , Martin A. Giese

Modeling continuous dynamical systems from discretely sampled observations is a fundamental problem in data science. Often, such dynamics are the result of non-local processes that present an integral over time. As such, these systems are…

Human-aligned deep learning models exhibit behaviors consistent with human values, such as robustness, fairness, and honesty. Transferring these behavioral properties to models trained on different tasks or data distributions remains…

Machine Learning · Computer Science 2025-06-02 Galen Pogoncheff , Michael Beyeler

The principled design and discovery of biologically- and physically-informed models of neuronal dynamics has been advancing since the mid-twentieth century. Recent developments in artificial intelligence (AI) have accelerated this progress.…

Neurons and Cognition · Quantitative Biology 2021-12-24 Mahta Ramezanian Panahi , Germán Abrevaya , Jean-Christophe Gagnon-Audet , Vikram Voleti , Irina Rish , Guillaume Dumas

Dynamic brain data, teeming with biological and functional insights, are becoming increasingly accessible through advanced measurements, providing a gateway to understanding the inner workings of the brain in living subjects. However, the…

Neurons and Cognition · Quantitative Biology 2025-08-19 Zixia Zhou , Junyan Liu , Wei Emma Wu , Ruogu Fang , Sheng Liu , Qingyue Wei , Rui Yan , Yi Guo , Qian Tao , Yuanyuan Wang , Md Tauhidul Islam , Lei Xing

Deep learning using neural networks has revolutionized machine learning and put artificial intelligence into everyday life. In order to introduce self-learning to dynamic systems other than neural networks, we extend the Brandt-Lin learning…

Systems and Control · Electrical Eng. & Systems 2023-08-22 Omar Makke , Feng Lin

Understanding human activity is very challenging even with the recently developed 3D/depth sensors. To solve this problem, this work investigates a novel deep structured model, which adaptively decomposes an activity instance into temporal…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Liang Lin , Keze Wang , Wangmeng Zuo , Meng Wang , Jiebo Luo , Lei Zhang

In the realm of autonomous driving, conventional approaches for vehicle perception and decision-making primarily rely on sensor input and rule-based algorithms. However, these methodologies often suffer from lack of interpretability and…

Robotics · Computer Science 2025-02-25 Haidong Wang , Pengfei Xiao , Ao Liu , Qia Shan , Jianhua Zhang

Brain-wide recordings of large-scale networks of neurons now provide an unprecedented view into how the brain drives behavior. However, brain activity contains both information directly related to behavior as well as the potential for many…

Neurons and Cognition · Quantitative Biology 2026-05-06 Eva Yezerets , En Yang , Misha B. Ahrens , Adam S. Charles

Dynamical modeling of multisite human intracranial neural recordings is essential for developing neurotechnologies such as brain-computer interfaces (BCIs). Linear dynamical models are widely used for this purpose due to their…

Neurons and Cognition · Quantitative Biology 2025-12-30 Kiarash Vaziri , Lucine L. Oganesian , HyeongChan Jo , Roberto M. C. Vera , Charles Y. Liu , Brian Lee , Maryam M. Shanechi

To fully understand, analyze, and determine the behavior of dynamical systems, it is crucial to identify their intrinsic modal coordinates. In nonlinear dynamical systems, this task is challenging as the modal transformation based on the…

Machine Learning · Computer Science 2025-03-13 Abdolvahhab Rostamijavanani , Shanwu Li , Yongchao Yang

Uncovering the fundamental neural correlates of biological intelligence, developing mathematical models, and conducting computational simulations are critical for advancing new paradigms in artificial intelligence (AI). In this study, we…

Neural and Evolutionary Computing · Computer Science 2024-09-05 Jie Su , Fang Cai , Shu-Kuo Zhao , Xin-Yi Wang , Tian-Yi Qian , Da-Hui Wang , Bo Hong

Neural population activity exhibits complex, nonlinear dynamics, varying in time, over trials, and across experimental conditions. Here, we develop Conditionally Linear Dynamical System (CLDS) models as a general-purpose method to…

Neurons and Cognition · Quantitative Biology 2025-10-31 Victor Geadah , Amin Nejatbakhsh , David Lipshutz , Jonathan W. Pillow , Alex H. Williams

Neural network modules conditioned by known priors can be effectively trained and combined to represent systems with nonlinear dynamics. This work explores a novel formulation for data-efficient learning of deep control-oriented nonlinear…

Dynamical Systems · Mathematics 2021-01-07 Elliott Skomski , Soumya Vasisht , Colby Wight , Aaron Tuor , Jan Drgona , Draguna Vrabie

Our ability to use deep learning approaches to decipher neural activity would likely benefit from greater scale, in terms of both model size and datasets. However, the integration of many neural recordings into one unified model is…

Neural-network-based dynamics models learned from observational data have shown strong predictive capabilities for scene dynamics in robotic manipulation tasks. However, their inherent non-linearity presents significant challenges for…

Robotics · Computer Science 2025-03-18 Keyi Shen , Jiangwei Yu , Jose Barreiros , Huan Zhang , Yunzhu Li

A body of recent work in modeling neural activity focuses on recovering low-dimensional latent features that capture the statistical structure of large-scale neural populations. Most such approaches have focused on linear generative models,…

Neurons and Cognition · Quantitative Biology 2016-10-26 Yuanjun Gao , Evan Archer , Liam Paninski , John P. Cunningham

Understanding neural activity and information representation is crucial for advancing knowledge of brain function and cognition. Neural activity, measured through techniques like electrophysiology and neuroimaging, reflects various aspects…

Neurons and Cognition · Quantitative Biology 2024-07-22 Fengyu Yang , Chao Feng , Daniel Wang , Tianye Wang , Ziyao Zeng , Zhiyang Xu , Hyoungseob Park , Pengliang Ji , Hanbin Zhao , Yuanning Li , Alex Wong
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