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The Average Gradient Outer Product (AGOP) governs feature learning in neural networks: the Neural Feature Ansatz states that weight Gram matrices at each layer align with the corresponding AGOP matrices computed over the training…

Machine Learning · Computer Science 2026-05-14 Raj Kiran Gupta Katakam

Motivated by the need for computationally tractable spatial methods in neuroimaging studies, we develop a distributed and integrated framework for estimation and inference of Gaussian process model parameters with ultra-high-dimensional…

Methodology · Statistics 2024-02-09 Emily C. Hector , Brian J. Reich , Ani Eloyan

Interpreting machine learning model decisions is crucial for high-risk applications like healthcare. In digital pathology, large whole slide images (WSIs) are decomposed into smaller tiles and tile-derived features are processed by…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Tomé Albuquerque , Anil Yüce , Markus D. Herrmann , Alvaro Gomariz

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Generative machine learning models offer a powerful framework for therapeutic design by efficiently exploring large spaces of biological sequences enriched for desirable properties. Unlike supervised learning methods, which require both…

Recent research has demonstrated that feature attribution methods for deep networks can themselves be incorporated into training; these attribution priors optimize for a model whose attributions have certain desirable properties -- most…

Machine Learning · Computer Science 2020-11-12 Gabriel Erion , Joseph D. Janizek , Pascal Sturmfels , Scott Lundberg , Su-In Lee

Decision trees are ubiquitous in machine learning for their ease of use and interpretability. Yet, these models are not typically employed in reinforcement learning as they cannot be updated online via stochastic gradient descent. We…

Machine Learning · Computer Science 2020-06-29 Andrew Silva , Taylor Killian , Ivan Dario Jimenez Rodriguez , Sung-Hyun Son , Matthew Gombolay

This study explores a novel approach to advancing dementia care by integrating socially assistive robotics, reinforcement learning (RL), large language models (LLMs), and clinical domain expertise within a simulated environment. This…

Artificial Intelligence · Computer Science 2025-01-30 Fengpei Yuan , Nehal Hasnaeen , Ran Zhang , Bryce Bible , Joseph Riley Taylor , Hairong Qi , Fenghui Yao , Xiaopeng Zhao

Grouping has been commonly used in deep metric learning for computing diverse features. However, current methods are prone to overfitting and lack interpretability. In this work, we propose an improved and interpretable grouping method to…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Xinyi Xu , Zhengyang Wang , Cheng Deng , Hao Yuan , Shuiwang Ji

Variational inference in Bayesian deep learning often involves computing the gradient of an expectation that lacks a closed-form solution. In these cases, pathwise and score-function gradient estimators are the most common approaches. The…

Machine Learning · Statistics 2024-10-10 Kenyon Ng , Susan Wei

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

Genomics · Quantitative Biology 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

Importance weighting (IW) is a golden solver for joint distribution shift, where the joint distributions differ between the training and test data. To solve this problem, IW estimates test-to-training density ratios as importance weights…

Machine Learning · Computer Science 2026-05-26 Tongtong Fang , Nan Lu , Gang Niu , Kenji Fukumizu , Masashi Sugiyama

Integrated Information Theory (IIT) has emerged as one of the leading research lines in computational neuroscience to provide a mechanistic and mathematically well-defined description of the neural correlates of consciousness. Integrated…

Quantum Physics · Physics 2018-12-11 Paolo Zanardi , Michael Tomka , Lorenzo Campos Venuti

Deep neural network models have been proven to be very successful in image classification tasks, also for medical diagnosis, but their main concern is its lack of interpretability. They use to work as intuition machines with high…

Machine Learning · Computer Science 2019-04-26 Jordi de la Torre , Aida Valls , Domenec Puig

Deep neural network training involves both forward propagation (from features through logits to loss) and backward propagation (from loss through gradients to parameter updates). While perturbations along the forward chain, including…

Machine Learning · Computer Science 2026-05-29 Hua Li

An emerging problem in trustworthy machine learning is to train models that produce robust interpretations for their predictions. We take a step towards solving this problem through the lens of axiomatic attribution of neural networks. Our…

Machine Learning · Computer Science 2019-10-29 Jiefeng Chen , Xi Wu , Vaibhav Rastogi , Yingyu Liang , Somesh Jha

The partially observable generalized linear model (POGLM) is a powerful tool for understanding neural connectivity under the assumption of existing hidden neurons. With spike trains only recorded from visible neurons, existing works use…

Machine Learning · Computer Science 2024-02-08 Chengrui Li , Weihan Li , Yule Wang , Anqi Wu

Interpreting the decision-making process of deep convolutional neural networks remains a central challenge in achieving trustworthy and transparent artificial intelligence. Explainable AI (XAI) techniques, particularly Class Activation Map…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Hajar Dekdegue , Moncef Garouani , Josiane Mothe , Jordan Bernigaud

Due to their high computational complexity, deep neural networks are still limited to powerful processing units. To promote a reduced model complexity by dint of low-bit fixed-point quantization, we propose a gradient-based optimization…

Machine Learning · Computer Science 2019-07-18 Lukas Enderich , Fabian Timm , Lars Rosenbaum , Wolfram Burgard

Deep learning systems often struggle with processing long sequences, where computational complexity can become a bottleneck. Current methods for automated dementia detection using speech frequently rely on static, time-agnostic features or…

Sound · Computer Science 2025-10-02 Chukwuemeka Ugwu , Oluwafemi Oyeleke