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We develop inductive biases for the machine learning of complex physical systems based on the port-Hamiltonian formalism. To satisfy by construction the principles of thermodynamics in the learned physics (conservation of energy,…

Machine Learning · Computer Science 2023-03-28 Quercus Hernández , Alberto Badías , Francisco Chinesta , Elías Cueto

Machine learning techniques paired with the availability of massive datasets dramatically enhance our ability to explore the chemical compound space by providing fast and accurate predictions of molecular properties. However, learning on…

A central open problem in nuclear physics is the determination of a physically robust equation of state (EoS) for dense nuclear matter, which directly informs our understanding of the internal composition and macroscopic properties of…

Nuclear Theory · Physics 2025-12-08 I. Stergakis , Th. Diakonidis , Ch. C. Moustakidis

We have investigated thermodynamic and dynamic properties as well as the dielectric constant of water-metha\-nol model mixtures in the entire range of composition by using constant pressure molecular dynamics simulations at ambient…

Soft Condensed Matter · Physics 2015-12-25 E. Galicia-Andrés , H. Dominguez , L. Pusztai , O. Pizio

Predicting the evolution of systems that exhibit spatio-temporal dynamics in response to external stimuli is a key enabling technology fostering scientific innovation. Traditional equations-based approaches leverage first principles to…

Machine Learning · Computer Science 2023-05-02 Francesco Regazzoni , Stefano Pagani , Matteo Salvador , Luca Dede' , Alfio Quarteroni

Scientific applications increasingly demand real-time surrogate models that can capture the behavior of strongly coupled multiphysics systems driven by multiple input functions, such as in thermo-mechanical and electro-thermal processes.…

Machine Learning · Computer Science 2025-07-08 Kazuma Kobayashi , Jaewan Park , Qibang Liu , Seid Koric , Diab Abueidda , Syed Bahauddin Alam

Molecular property prediction is essential in a variety of contemporary scientific fields, such as drug development and designing energy storage materials. Although there are many machine learning models available for this purpose, those…

Machine Learning · Computer Science 2025-06-03 Gihan Panapitiya , Peiyuan Gao , C Mark Maupin , Emily G Saldanha

Graph neural networks for molecular property prediction are frequently underspecified by data and fail to generalise to new scaffolds at test time. A potential solution is Bayesian learning, which can capture our uncertainty in the model…

Biomolecules · Quantitative Biology 2020-12-04 George Lamb , Brooks Paige

A deep neural network was developed for the purpose of predicting thermal conductivity with a case study performed on neutron irradiated nuclear fuel. Traditional thermal conductivity modeling approaches rely on existing theoretical…

Materials Science · Physics 2019-01-04 Elizabeth Kautz , Alexander Hagen , Jesse Johns , Douglas Burkes

The calculation of reactive properties is a challenging task in chemical reaction discovery. Machine learning (ML) methods play an important role in accelerating electronic structure predictions of activation energies and reaction…

Chemical Physics · Physics 2025-05-02 Joe Gilkes , Mark Storr , Reinhard J. Maurer , Scott Habershon

A major bottleneck in developing sustainable processes and materials is a lack of property data. Recently, machine learning approaches have vastly improved previous methods for predicting molecular properties. However, these machine…

Chemical Physics · Physics 2023-09-25 Benedikt Winter , Philipp Rehner , Timm Esper , Johannes Schilling , André Bardow

Predicting the physico-chemical properties of pure substances and mixtures is a central task in thermodynamics. Established prediction methods range from fully physics-based ab-initio calculations, which are only feasible for very simple…

Machine Learning · Computer Science 2024-12-02 Johannes Zenn , Dominik Gond , Fabian Jirasek , Robert Bamler

Deep learning is a potential approach to automatically develop kinetic models from experimental data. We propose a deep neural network model of KiNet to represent chemical kinetics. KiNet takes the current composition states and predicts…

Computational Physics · Physics 2021-08-03 Weiqi Ji , Sili Deng

Recent years have seen a significant increase in the use of machine intelligence for predicting electronic structure, molecular force fields, and the physicochemical properties of various condensed systems. However, substantial challenges…

Chemical Physics · Physics 2023-11-10 Jianzhong Wu , Mengyang Gu

Modeling buildings' heat dynamics is a complex process which depends on various factors including weather, building thermal capacity, insulation preservation, and residents' behavior. Gray-box models offer a causal inference of those…

Machine Learning · Computer Science 2019-02-20 Nilavra Pathak , James Foulds , Nirmalya Roy , Nilanjan Banerjee , Ryan Robucci

Atomistic simulations of properties of materials at finite temperatures are computationally demanding and require models that are more efficient than the ab initio approaches. Machine learning (ML) and artificial intelligence (AI) address…

Materials Science · Physics 2024-12-05 Alex Kutana , Koki Yoshimochi , Ryoji Asahi

Molecular property prediction integrates quantum chemistry, cheminformatics, and deep learning to connect molecular structure with physicochemical and biological behavior. This survey traces four complementary paradigms, including Quantum,…

The hydrogen trapping behaviour of metallic alloys is generally characterised using Thermal Desorption Spectroscopy (TDS). However, as an indirect method, extracting key parameters (trap binding energies and densities) remains a significant…

Machine Learning · Computer Science 2025-08-06 N. Marrani , T. Hageman , E. Martínez-Pañeda

Crystal property prediction, governed by quantum mechanical principles, is computationally prohibitive to solve exactly for large many-body systems using traditional density functional theory. While machine learning models have emerged as…

Materials Science · Physics 2026-01-28 Bin Cao , Yang Liu , Longhan Zhang , Yifan Wu , Zhixun Li , Yuyu Luo , Hong Cheng , Yang Ren , Tong-Yi Zhang

Due to its non-crystalline nature, the glassy state has remained one the most exciting scientific challenges. To study such materials, Molecular Dynamics (MD) simulations have been extensively used because they provide a direct view into…

Materials Science · Physics 2015-06-23 Mathieu Bauchy
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