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Bayesian Graph Neural Networks for Molecular Property Prediction

Biomolecules 2020-12-04 v1 Machine Learning

Abstract

Graph neural networks for molecular property prediction are frequently underspecified by data and fail to generalise to new scaffolds at test time. A potential solution is Bayesian learning, which can capture our uncertainty in the model parameters. This study benchmarks a set of Bayesian methods applied to a directed MPNN, using the QM9 regression dataset. We find that capturing uncertainty in both readout and message passing parameters yields enhanced predictive accuracy, calibration, and performance on a downstream molecular search task.

Keywords

Cite

@article{arxiv.2012.02089,
  title  = {Bayesian Graph Neural Networks for Molecular Property Prediction},
  author = {George Lamb and Brooks Paige},
  journal= {arXiv preprint arXiv:2012.02089},
  year   = {2020}
}

Comments

Presented at NeurIPS 2020 Machine Learning for Molecules workshop

R2 v1 2026-06-23T20:42:42.668Z