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Microbiome interventions provide valuable data about microbial ecosystem structure and dynamics. Despite their ubiquity in microbiome research, few rigorous data analysis approaches are available. In this study, we extend transfer…

Applications · Statistics 2023-06-13 Kris Sankaran , Pratheepa Jeganathan

Accurate estimates of microbial species abundances are needed to advance our understanding of the role that microbiomes play in human and environmental health. However, artificially constructed microbiomes demonstrate that intuitive…

Methodology · Statistics 2025-03-17 David S Clausen , Amy D Willis

We analyze different types of simulations that applied researchers can use to assess whether their inference methods reliably control false-positive rates. We show that different assessments involve trade-offs, varying in the types of…

Econometrics · Economics 2025-10-03 Bruno Ferman

Machine learning (ML) is poised to drive innovations in clinical microbiomics, such as in disease diagnostics and prognostics. However, the successful implementation of ML in these domains necessitates the development of reproducible,…

Genomics · Quantitative Biology 2024-12-02 Natasha K. Dudek , Mariam Chakhvadze , Saba Kobakhidze , Omar Kantidze , Yuriy Gankin

Correlation coefficient is widely used in biomedical and biological literature, yet its frequent misuse and misinterpretation undermine the credibility and reproducibility of the scientific findings. We systematically reviewed 1326 records…

Methodology · Statistics 2025-11-19 Jiayang Xu , Xintong Chen , Yufeng Liu , Xiaoli Guo , Shanbao Tong

In biomedical and public health association studies, binary outcome variables may be subject to misclassification, resulting in substantial bias in effect estimates. The feasibility of addressing binary outcome misclassification in…

Methodology · Statistics 2024-03-19 Kimberly A. Hochstedler Webb , Martin T. Wells

In this paper, some points to the convergence analysis performed in the paper [A new computing approach for power signal modeling using fractional adaptive algorithms, ISA Transactions 68 (2017) 189-202] are presented. It is highlighted…

Optimization and Control · Mathematics 2020-03-24 Abdul Wahab , Shujaat Khan , Farrukh Zeeshan Khan

Medical imaging is an important research field with many opportunities for improving patients' health. However, there are a number of challenges that are slowing down the progress of the field as a whole, such optimizing for publication. In…

Image and Video Processing · Electrical Eng. & Systems 2022-05-14 Gaël Varoquaux , Veronika Cheplygina

A recent paper [1] (El Aroudi, 2012) misapplied a critical condition (Fang and Abed, 2001) to a well-known example. Even if the mistake is corrected, the results in [1] are applicable only to buck converters and period-doubling bifurcation.…

Systems and Control · Computer Science 2015-03-20 Chung-Chieh Fang

Many researchers have identified distribution shift as a likely contributor to the reproducibility crisis in behavioral and biomedical sciences. The idea is that if treatment effects vary across individual characteristics and experimental…

Applications · Statistics 2023-09-06 Ying Jin , Kevin Guo , Dominik Rothenhäusler

Information extracted from electrohysterography recordings could potentially prove to be an interesting additional source of information to estimate the risk on preterm birth. Recently, a large number of studies have reported near-perfect…

Estimating nonlinear functionals of probability distributions from samples is a fundamental statistical problem. The "plug-in" estimator obtained by applying the target functional to the empirical distribution of samples is biased.…

Statistics Theory · Mathematics 2026-02-20 Florian Schäfer

Diagnosing and mitigating changes in model fairness under distribution shift is an important component of the safe deployment of machine learning in healthcare settings. Importantly, the success of any mitigation strategy strongly depends…

In particle physics, as in many areas of science, parameter inference relies on simulations to bridge the gap between theory and experiment. Recent developments in simulation-based inference have boosted the sensitivity of analyses;…

High Energy Physics - Phenomenology · Physics 2026-04-23 Ezequiel Alvarez , Sean Benevedes , Manuel Szewc , Jesse Thaler

This paper offers a synthesis of the empirical literature on the effects of monetary policy. Using the findings from an extensive collection of meta-analyses, it evaluates the effectiveness of conventional and unconventional monetary policy…

Theoretical Economics · Economics 2025-09-25 Ricardo Alonzo Fernandez Salguero

Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

Machine Learning · Computer Science 2025-08-01 Rabeya Tus Sadia , Qiang Cheng

Numerous studies have shown that microbial metabolites, which represent the products of bacteria in the human gut, play a key role in shaping cancer risk and response to treatment. However, metabolite data typically contain a large…

Applications · Statistics 2026-05-19 Kai Jiang , Satabdi Saha , Christine B. Peterson

In the note two errors in Low and Lapsley's article "Optimization Flow Control, I: Basic Algorithm and Convergence", "IEEE/ACM Transactions on Networking", 7(6), pp. 861-874, 1999, are shown. Because of these errors the proofs of both…

Networking and Internet Architecture · Computer Science 2016-10-11 Andrzej Karbowski

This paper proposes a hierarchical Bayesian multitask learning model that is applicable to the general multi-task binary classification learning problem where the model assumes a shared sparsity structure across different tasks. We derive a…

Analysis of survival data with biased samples caused by left-truncation or length-biased sampling has received extensive interest. Many inference methods have been developed for various survival models. These methods, however, break down…

Statistics Theory · Mathematics 2018-12-31 Li-Pang Chen
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