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Integrating artificial intelligence (AI) with healthcare data is rapidly transforming medical diagnostics and driving progress toward precision medicine. However, effectively leveraging multimodal data, particularly digital pathology whole…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Areej Alsaafin , Abubakr Shafique , Saghir Alfasly , Krishna R. Kalari , H. R. Tizhoosh

Multimodal Sentiment Analysis is an active area of research that leverages multimodal signals for affective understanding of user-generated videos. The predominant approach, addressing this task, has been to develop sophisticated fusion…

Computation and Language · Computer Science 2020-10-20 Devamanyu Hazarika , Roger Zimmermann , Soujanya Poria

Establishing dense anatomical correspondence across distinct imaging modalities is a foundational yet challenging procedure for numerous medical image analysis studies and image-guided radiotherapy. Existing multi-modality image…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Tony C. W. Mok , Zi Li , Yunhao Bai , Jianpeng Zhang , Wei Liu , Yan-Jie Zhou , Ke Yan , Dakai Jin , Yu Shi , Xiaoli Yin , Le Lu , Ling Zhang

Joint embeddings between medical imaging modalities and associated radiology reports have the potential to offer significant benefits to the clinical community, ranging from cross-domain retrieval to conditional generation of reports to the…

Machine Learning · Computer Science 2018-11-28 Tzu-Ming Harry Hsu , Wei-Hung Weng , Willie Boag , Matthew McDermott , Peter Szolovits

The acquisition of different data modalities can enhance our knowledge and understanding of various diseases, paving the way for a more personalized healthcare. Thus, medicine is progressively moving towards the generation of massive…

Image and Video Processing · Electrical Eng. & Systems 2024-05-06 Tiago Mota , M. Rita Verdelho , Alceu Bissoto , Carlos Santiago , Catarina Barata

We present a tool for resolution recovery in multimodal clinical magnetic resonance imaging (MRI). Such images exhibit great variability, both biological and instrumental. This variability makes automated processing with neuroimaging…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Mikael Brudfors , Yael Balbastre , Parashkev Nachev , John Ashburner

Background: The integration of multi-stain histopathology images through deep learning poses a significant challenge in digital histopathology. Current multi-modal approaches struggle with data heterogeneity and missing data. This study…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Valentin Koch , Sabine Bauer , Valerio Luppberger , Michael Joner , Heribert Schunkert , Julia A. Schnabel , Moritz von Scheidt , Carsten Marr

Multimodal learning is susceptible to modality missing, which poses a major obstacle for its practical applications and, thus, invigorates increasing research interest. In this paper, we investigate two challenging problems: 1) when…

Machine Learning · Computer Science 2023-12-19 Jun Sun , Xinxin Zhang , Shoukang Han , Yu-ping Ruan , Taihao Li

Early multiple sclerosis (MS) disability progression prediction is challenging due to disease heterogeneity. This work predicts 48- and 72-week disability using sparse baseline clinical data and 12 weeks of daily digital Floodlight data…

Machine Learning · Computer Science 2025-06-19 Maxime Usdin , Lito Kriara , Licinio Craveiro

An incomplete field-of-view (FOV) in diffusion magnetic resonance imaging (dMRI) can severely hinder the volumetric and bundle analyses of whole-brain white matter connectivity. Although existing works have investigated imputing the missing…

We present an end-to-end deep learning framework for automated liver cirrhosis stage estimation from multi-sequence MRI. Cirrhosis is the severe scarring (fibrosis) of the liver and a common endpoint of various chronic liver diseases. Early…

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Lijun Yan , Churan Wang , Fangwei Zhong , Yizhou Wang

Audio-visual learning helps to comprehensively understand the world by fusing practical information from multiple modalities. However, recent studies show that the imbalanced optimization of uni-modal encoders in a joint-learning model is a…

Sound · Computer Science 2023-03-14 Ruize Xu , Ruoxuan Feng , Shi-Xiong Zhang , Di Hu

Healthcare data now span EHRs, medical imaging, genomics, and wearable sensors, but most diagnostic models still process these modalities in isolation. This limits their ability to capture early, cross-modal disease signatures. This paper…

Machine Learning · Computer Science 2025-12-18 Md Talha Mohsin , Ismail Abdulrashid

In healthcare, the integration of multimodal data is pivotal for developing comprehensive diagnostic and predictive models. However, managing missing data remains a significant challenge in real-world applications. We introduce MARIA…

Machine Learning · Computer Science 2026-03-13 Camillo Maria Caruso , Paolo Soda , Valerio Guarrasi

Medical records often consist of different modalities, such as images, text, and tabular information. Integrating all modalities offers a holistic view of a patient's condition, while analyzing them longitudinally provides a better…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Boqi Chen , Junier Oliva , Marc Niethammer

Multi-modal image segmentation faces real-world deployment challenges from incomplete/corrupted modalities degrading performance. While existing methods address training-inference modality gaps via specialized per-combination models, they…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Xiaoqi Zhao , Youwei Pang , Chenyang Yu , Lihe Zhang , Huchuan Lu , Shijian Lu , Georges El Fakhri , Xiaofeng Liu

Multimodal learning, which integrates diverse data sources such as images, text, and structured data, has proven superior to unimodal counterparts in high-stakes decision-making. However, while performance gains remain the gold standard for…

Artificial Intelligence · Computer Science 2025-05-07 Kishore Sampath , Pratheesh , Ayaazuddin Mohammad , Resmi Ramachandranpillai

Multimodal recommender systems (RSs) represent items in the catalog through multimodal data (e.g., product images and descriptions) that, in some cases, might be noisy or (even worse) missing. In those scenarios, the common practice is to…

Information Retrieval · Computer Science 2026-02-20 Daniele Malitesta , Emanuele Rossi , Claudio Pomo , Tommaso Di Noia , Fragkiskos D. Malliaros

Accurate diagnosis of glaucoma is challenging, as early-stage changes are subtle and often lack clear structural or appearance cues. Most existing approaches rely on a single modality, such as fundus or optical coherence tomography (OCT),…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Zhiwei Wang , Yuxing Li , Meilu Zhu , Defeng He , Edmund Y. Lam