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Multiple sclerosis (MS) is a demyelinating disease that affects more than 2 million people worldwide. The most used imaging technique to help in its diagnosis and follow-up is magnetic resonance imaging (MRI). Fluid Attenuated Inversion…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Paulo G. L. Freire , Ricardo J. Ferrari

In medical vision, different imaging modalities provide complementary information. However, in practice, not all modalities may be available during inference or even training. Previous approaches, e.g., knowledge distillation or image…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Aishik Konwer , Xiaoling Hu , Joseph Bae , Xuan Xu , Chao Chen , Prateek Prasanna

Multimodal MR images can provide complementary information for accurate brain tumor segmentation. However, it's common to have missing imaging modalities in clinical practice. Since there exists a strong correlation between multi…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

Medical foundation models (MFMs) aim to learn universal representations from multimodal medical images that can generalize effectively to diverse downstream clinical tasks. However, most existing MFMs suffer from information ambiguity that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Yihang Liu , Longzhen Yang , Jiaxiong Yang , Ying Wen , Lianghua He , Heng Tao Shen

The integration of multi-modal Magnetic Resonance Imaging (MRI) and clinical data holds great promise for enhancing the diagnosis of neurological disorders (NDs) in real-world clinical settings. Deep Learning (DL) has recently emerged as a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Wajih Hassan Raza , Aamir Bader Shah , Yu Wen , Yidan Shen , Juan Diego Martinez Lemus , Mya Caryn Schiess , Timothy Michael Ellmore , Renjie Hu , Xin Fu

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Multimodal sentiment analysis relies on textual, acoustic, and visual signals, yet real-world data often suffer from modality missing and quality imbalance. Existing methods generate features for modality missing from available ones, but…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Chenglizhao Chen , Yuchen Cao , Xinyu Liu , Mengke Song , Guisheng Zhang , Xiaomin Yu

Multimodal ophthalmic imaging-based diagnosis integrates color fundus image with optical coherence tomography (OCT) to provide a comprehensive view of ocular pathologies. However, the uneven global distribution of healthcare resources often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Qinkai Yu , Jianyang Xie , Yitian Zhao , Cheng Chen , Lijun Zhang , Liming Chen , Jun Cheng , Lu Liu , Yalin Zheng , Yanda Meng

Purpose: Deep learning methods have shown promising results in the segmentation, and detection of diseases in medical images. However, most methods are trained and tested on data from a single source, modality, organ, or disease type,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Nchongmaje Ndipenocha , Alina Mirona , Kezhi Wanga , Yongmin Li

Multimodal Magnetic Resonance (MR) Imaging plays a crucial role in disease diagnosis due to its ability to provide complementary information by analyzing a relationship between multimodal images on the same subject. Acquiring all MR…

Image and Video Processing · Electrical Eng. & Systems 2024-02-02 Jihoon Cho , Xiaofeng Liu , Fangxu Xing , Jinsong Ouyang , Georges El Fakhri , Jinah Park , Jonghye Woo

Multi-modal magnetic resonance imaging (MRI) plays a crucial role in comprehensive disease diagnosis in clinical medicine. However, acquiring certain modalities, such as T2-weighted images (T2WIs), is time-consuming and prone to be with…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Qi Wang , Zhijie Wen , Jun Shi , Qian Wang , Dinggang Shen , Shihui Ying

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

While multi-modal learning has been widely used for MRI reconstruction, it relies on paired multi-modal data which is difficult to acquire in real clinical scenarios. Especially in the federated setting, the common situation is that several…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Yunlu Yan , Chun-Mei Feng , Yuexiang Li , Rick Siow Mong Goh , Lei Zhu

Robust localization of lymph nodes (LNs) in multiparametric MRI (mpMRI) is critical for the assessment of lymphadenopathy. Radiologists routinely measure the size of LN to distinguish benign from malignant nodes, which would require…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tejas Sudharshan Mathai , Sungwon Lee , Thomas C. Shen , Zhiyong Lu , Ronald M. Summers

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

Recent studies on T1-assisted MRI reconstruction for under-sampled images of other modalities have demonstrated the potential of further accelerating MRI acquisition of other modalities. Most of the state-of-the-art approaches have achieved…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Junwei Yang , Xiao-Xin Li , Feihong Liu , Dong Nie , Pietro Lio , Haikun Qi , Dinggang Shen

Multimodal learning integrates information from different modalities to enhance model performance, yet it often suffers from modality imbalance, where dominant modalities overshadow weaker ones during joint optimization. This paper reveals…

Machine Learning · Computer Science 2025-10-17 Xiaoyu Ma , Hao Chen

Medical image recognition serves as a key way to aid in clinical diagnosis, enabling more accurate and timely identification of diseases and abnormalities. Vision transformer-based approaches have proven effective in handling various…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Zunhui Xia , Hongxing Li , Libin Lan

Medical imaging is a cornerstone of therapy and diagnosis in modern medicine. However, the choice of imaging modality for a particular theranostic task typically involves trade-offs between the feasibility of using a particular modality…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Mayur Mallya , Ghassan Hamarneh