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Related papers: TractoTransformer: Diffusion MRI Streamline Tracto…

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Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…

As tractography datasets continue to grow in size, there is a need for improved visualization methods that can capture structural patterns occurring in large tractography datasets. Transparency is an increasingly important aspect of finding…

Graphics · Computer Science 2023-08-17 Besm Osman , Mestiez Pereira , Huub van de Wetering , Maxime Chamberland

Inferring which pathways are affected by a brain lesion is key for both pre and post-treatment planning. However, many disruptive lesions cause changes in the tissue that interrupt tractography algorithms. In such cases, aggregating…

Quantitative Methods · Quantitative Biology 2021-10-05 Guillermo Gallardo , Gaston Zanitti , Mat Higger , Sylvain Bouix , Demian Wassermann

Tractograms are virtual representations of the white matter fibers of the brain. They are of primary interest for tasks like presurgical planning, and investigation of neuroplasticity or brain disorders. Each tractogram is composed of…

Neurons and Cognition · Quantitative Biology 2020-07-10 Pietro Astolfi , Ruben Verhagen , Laurent Petit , Emanuele Olivetti , Jonathan Masci , Davide Boscaini , Paolo Avesani

Tractography is typically performed for each subject using the diffusion tensor imaging (DTI) data in its native subject space rather than in some space common to the entire study cohort. Despite performing tractography on a population…

Fiber tracking based on diffusion weighted Magnetic Resonance Imaging (dMRI) allows for noninvasive reconstruction of fiber bundles in the human brain. In this chapter, we discuss sources of error and uncertainty in this technique, and…

Computer Vision and Pattern Recognition · Computer Science 2013-07-15 Thomas Schultz , Anna Vilanova , Ralph Brecheisen , Gordon Kindlmann

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

Subtle changes in white matter (WM) microstructure have been associated with normal aging and neurodegeneration. To study these associations in more detail, it is highly important that the WM tracts can be accurately and reproducibly…

Image and Video Processing · Electrical Eng. & Systems 2020-05-27 Bo Li , Marius de Groot , Rebecca M. E. Steketee , Rozanna Meijboom , Marion Smits , Meike W. Vernooij , M. Arfan Ikram , Jiren Liu , Wiro J. Niessen , Esther E. Bron

We present a geometric framework for aligning white matter fiber tracts. By registering fiber tracts between brains, one expects to see overlap of anatomical structures that often provide meaningful comparisons across subjects. However, the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Andrew Lizarraga , David Lee , Antoni Kubicki , Ashish Sahib , Elvis Nunez , Katherine Narr , Shantanu H. Joshi

Tractography algorithms are used extensively to delineate white matter structures, by operating on the voxel-wise information generated through the application of diffusion tensor imaging (DTI) or other models to diffusion weighted (DW)…

Quantitative Methods · Quantitative Biology 2024-03-05 Richard G. Carson , Alexander Leemans

White matter parcellation classifies tractography streamlines into clusters or anatomically meaningful tracts to enable quantification and visualization. Most parcellation methods focus on the deep white matter (DWM), while fewer methods…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Tengfei Xue , Fan Zhang , Chaoyi Zhang , Yuqian Chen , Yang Song , Nikos Makris , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

Ultra-low-field (ULF) MRI is emerging as an alternative modality to high-field (HF) MRI due to its lower cost, minimal siting requirements, portability, and enhanced accessibility factors that enable large-scale deployment. Although ULF-MRI…

We present a novel dual-encoded magnetization transfer (MT) and diffusion-weighted sequence and demonstrate its potential to resolve distinct properties of white matter fiber tracts at the sub-voxel level. The sequence was designed and…

The study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool…

This paper presents DDTracking, a novel deep generative framework for diffusion MRI tractography that formulates streamline propagation as a conditional denoising diffusion process. In DDTracking, we introduce a dual-pathway encoding…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Yijie Li , Wei Zhang , Xi Zhu , Ye Wu , Yogesh Rathi , Lauren J. O'Donnell , Fan Zhang

In the human brain, white matter development is a complex and long-lasting process involving intermingling micro-and macrostructural mechanisms, such as fiber growth, pruning and myelination. Did you know that all these neurodevelopmental…

Neurons and Cognition · Quantitative Biology 2025-04-30 Jessica Dubois , Mareike Grotheer , Joseph Yuan-Mou Yang , Jacques-Donald Tournier , Christian Beaulieu , Catherine Lebel

Brain tissue segmentation has demonstrated great utility in quantifying MRI data through Voxel-Based Morphometry and highlighting subtle structural changes associated with various conditions within the brain. However, manual segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-02 Vishwanatha M. Rao , Zihan Wan , Soroush Arabshahi , David J. Ma , Pin-Yu Lee , Ye Tian , Xuzhe Zhang , Andrew F. Laine , Jia Guo

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

Diffusion magnetic resonance imaging, a non-invasive tool to infer white matter fiber connections, produces a large number of streamlines containing a wealth of information on structural connectivity. The size of these tractography outputs…

Computer Vision and Pattern Recognition · Computer Science 2018-04-17 Kuldeep Kumar , Kaleem Siddiqi , Christian Desrosiers

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…