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By coupling peptides with DNA tags (i.e., 'barcodes'), it is now possible to harness high-throughput sequencing (HTS) technologies to enable highly multiplexed peptide-based assays, which have a variety of potential applications including…

Quantitative Methods · Quantitative Biology 2020-07-13 Zane W. Fink , Vidal Martinez , John Altin , Jason T. Ladner

There is a compelling demand for the data integration and exploitation of heterogeneous biomedical information for improved clinical practice, medical research, and personalised healthcare across the EU. The area of paediatric information…

Databases · Computer Science 2014-02-25 Richard McClatchey

We introduce DataCI, a comprehensive open-source platform designed specifically for data-centric AI in dynamic streaming data settings. DataCI provides 1) an infrastructure with rich APIs for seamless streaming dataset management,…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-04 Huaizheng Zhang , Yizheng Huang , Yuanming Li

Secure and scalable data sharing is essential for collaborative clinical decision making. Conventional clinical data efforts are often siloed, however, which creates barriers to efficient information exchange and impedes effective treatment…

Computers and Society · Computer Science 2018-07-11 Peng Zhang , Jules White , Douglas C. Schmidt , Gunther Lenz , S. Trent Rosenbloom

The library scikit-fda is a Python package for Functional Data Analysis (FDA). It provides a comprehensive set of tools for representation, preprocessing, and exploratory analysis of functional data. The library is built upon and integrated…

With the rapid development of computer software and hardware technologies, more and more healthcare data are becoming readily available from clinical institutions, patients, insurance companies and pharmaceutical industries, among others.…

Machine Learning · Computer Science 2020-08-24 Jie Xu , Benjamin S. Glicksberg , Chang Su , Peter Walker , Jiang Bian , Fei Wang

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor…

Whole Slide Image (WSI) analysis plays a crucial role in modern digital pathology, enabling large-scale feature extraction from tissue samples. However, traditional feature extraction pipelines based on tools like CellProfiler often involve…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Yuechen Yang , Yu Wang , Tianyuan Yao , Ruining Deng , Mengmeng Yin , Shilin Zhao , Haichun Yang , Yuankai Huo

SOFIA presents a number of interesting challenges for the development of a data reduction environment which, at its initial phase, will have to incorporate pipelines from seven different instruments. Therefore, the SOFIA data reduction…

Instrumentation and Methods for Astrophysics · Physics 2015-03-17 M. V. Charcos-Llorens , R. Krzaczek , R. Y. Shuping , L. Lin

Research in ultrasound imaging is limited in reproducibility by two factors: First, many existing ultrasound pipelines are protected by intellectual property, rendering exchange of code difficult. Second, most pipelines are implemented in…

Computer Vision and Pattern Recognition · Computer Science 2018-05-11 Rüdiger Göbl , Nassir Navab , Christoph Hennersperger

Managing personal health data is a challenge in today's fragmented and institution-centric healthcare ecosystem. Individuals often lack meaningful control over their medical records, which are scattered across incompatible systems and…

Multimedia · Computer Science 2026-02-24 Sujaya Maiyya , Shantanu Sharma , Avinash Kumar

Digital health applications that leverage multiple sources of patient data for insights to patients' behaviours or disease symptoms as well as remote patient monitoring, nudging and treatments are becoming increasingly popular in various…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-06-25 Wenhao Li , Niranjan Bidargaddi , John Fouyaxis

Individual health data is crucial for scientific advancements, particularly in developing Artificial Intelligence (AI); however, sharing real patient information is often restricted due to privacy concerns. A promising solution to this…

For clinical data integration and healthcare services, the HL7 FHIR standard has established itself as a desirable format for interoperability between complex health data. Previous attempts at automating the translation from free-form…

Computation and Language · Computer Science 2026-04-21 Johann Frei , Nils Feldhus , Lisa Raithel , Roland Roller , Alexander Meyer , Frank Kramer

Data de-identification makes it possible to glean insights from data while preserving user privacy. The use of Trusted Execution Environments (TEEs) allow for the execution of de-identification applications on the cloud without the need for…

Electronic Health Records (EHR) have revolutionized healthcare by digitizing patient data, improving accessibility, and streamlining clinical workflows. However, extracting meaningful insights from these complex and multimodal datasets…

Artificial Intelligence · Computer Science 2025-10-27 Naama Kashani , Mira Cohen , Uri Shaham

The extraction of relevant data from Electronic Health Records (EHRs) is crucial to identifying symptoms and automating epidemiological surveillance processes. By harnessing the vast amount of unstructured text in EHRs, we can detect…

Computation and Language · Computer Science 2025-02-10 Juliano Genari , Guilherme Tegoni Goedert

DAPHNE is a new open-source software infrastructure designed to address the increasing demands of integrated data analysis (IDA) pipelines, comprising data management (DM), high performance computing (HPC), and machine learning (ML)…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-04 Ahmed Eleliemy , Florina M. Ciorba

The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is…

Machine Learning · Computer Science 2023-12-25 Aakash Tripathi , Asim Waqas , Kavya Venkatesan , Yasin Yilmaz , Ghulam Rasool

We present Pipe3D, an analysis pipeline based on the FIT3D fitting tool, devel- oped to explore the properties of the stellar populations and ionized gas of Integral Field Spectroscopy data. Pipe3D was created to provide with coherent,…