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Antibiotics are a vital class of drugs closely associated with the prevention and treatment of bacterial infections. Accurate prediction of molecular antimicrobial activity remains a key challenge in the pursuit of novel antibiotic…

Quantitative Methods · Quantitative Biology 2025-09-23 R. He

We present an automatic mortality prediction scheme based on the unstructured textual content of clinical notes. Proposing a convolutional document embedding approach, our empirical investigation using the MIMIC-III intensive care database…

Computation and Language · Computer Science 2016-12-05 Paulina Grnarova , Florian Schmidt , Stephanie L. Hyland , Carsten Eickhoff

Word embeddings, made widely popular in 2013 with the release of word2vec, have become a mainstay of NLP engineering pipelines. Recently, with the release of BERT, word embeddings have moved from the term-based embedding space to the…

Information Retrieval · Computer Science 2022-02-17 Arthur Câmara , Claudia Hauff

Contextual word embeddings (e.g. GPT, BERT, ELMo, etc.) have demonstrated state-of-the-art performance on various NLP tasks. Recent work with the multilingual version of BERT has shown that the model performs very well in zero-shot and…

Computation and Language · Computer Science 2020-03-23 Phillip Keung , Yichao Lu , Vikas Bhardwaj

In this study, we implement a novel BERT architecture for multitask fine-tuning on three downstream tasks: sentiment classification, paraphrase detection, and semantic textual similarity prediction. Our model, Multitask BERT, incorporates…

Computation and Language · Computer Science 2024-08-29 Christopher Sun , Abishek Satish

The success of pre-trained word embeddings has motivated its use in tasks in the biomedical domain. The BERT language model has shown remarkable results on standard performance metrics in tasks such as Named Entity Recognition (NER) and…

Computation and Language · Computer Science 2020-04-24 Vladimir Araujo , Andres Carvallo , Carlos Aspillaga , Denis Parra

The absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties are important in drug discovery as they define efficacy and safety. In this work, we applied an ensemble of features, including fingerprints and…

Biomolecules · Quantitative Biology 2022-09-20 Hao Tian , Rajas Ketkar , Peng Tao

Antimicrobial resistance (AMR) poses a significant public health and economic challenge, increasing treatment costs and reducing antibiotic effectiveness. This study employs machine learning to analyze genomic and epidemiological data from…

Quantitative Methods · Quantitative Biology 2025-09-05 Shubham Mishra , The Anh Han , Bruno Silvester Lopes , Shatha Ghareeb , Zia Ush Shamszaman

Deep learning (DL) based predictive models from electronic health records (EHR) deliver impressive performance in many clinical tasks. Large training cohorts, however, are often required to achieve high accuracy, hindering the adoption of…

Computation and Language · Computer Science 2020-05-27 Laila Rasmy , Yang Xiang , Ziqian Xie , Cui Tao , Degui Zhi

Human decision-making differs due to variation in both incentives and available information. This constitutes a substantial challenge for the evaluation of whether and how machine learning predictions can improve decision outcomes. We…

General Economics · Economics 2020-11-24 Michael Allan Ribers , Hannes Ullrich

We present FireBERT, a set of three proof-of-concept NLP classifiers hardened against TextFooler-style word-perturbation by producing diverse alternatives to original samples. In one approach, we co-tune BERT against the training data and…

Computation and Language · Computer Science 2020-08-11 Gunnar Mein , Kevin Hartman , Andrew Morris

To combat adversarial spelling mistakes, we propose placing a word recognition model in front of the downstream classifier. Our word recognition models build upon the RNN semi-character architecture, introducing several new backoff…

Computation and Language · Computer Science 2019-08-30 Danish Pruthi , Bhuwan Dhingra , Zachary C. Lipton

Adversarial attacks for discrete data (such as texts) have been proved significantly more challenging than continuous data (such as images) since it is difficult to generate adversarial samples with gradient-based methods. Current…

Computation and Language · Computer Science 2020-10-05 Linyang Li , Ruotian Ma , Qipeng Guo , Xiangyang Xue , Xipeng Qiu

Sentence embeddings encode sentences in fixed dense vectors and have played an important role in various NLP tasks and systems. Methods for building sentence embeddings include unsupervised learning such as Quick-Thoughts and supervised…

Computation and Language · Computer Science 2021-06-10 Danqi Liao

Backdoor attacks are an insidious security threat against machine learning models. Adversaries can manipulate the predictions of compromised models by inserting triggers into the training phase. Various backdoor attacks have been devised…

Computation and Language · Computer Science 2023-05-29 Xuanli He , Jun Wang , Benjamin Rubinstein , Trevor Cohn

Recently proposed BERT-based evaluation metrics for text generation perform well on standard benchmarks but are vulnerable to adversarial attacks, e.g., relating to information correctness. We argue that this stems (in part) from the fact…

Computation and Language · Computer Science 2023-12-27 Yanran Chen , Steffen Eger

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

Computers and Society · Computer Science 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

New antibiotics are needed to battle growing antibiotic resistance, but the development process from hit, to lead, and ultimately to a useful drug, takes decades. Although progress in molecular property prediction using machine-learning…

Recent developments in adversarial attacks on deep learning leave many mission-critical natural language processing (NLP) systems at risk of exploitation. To address the lack of computationally efficient adversarial defense methods, this…

Computation and Language · Computer Science 2024-10-17 Hao-Yuan Chang , Kang L. Wang

Pre-trained language models (PLMs) have consistently demonstrated outstanding performance across a diverse spectrum of natural language processing tasks. Nevertheless, despite their success with unseen data, current PLM-based…

Computation and Language · Computer Science 2024-03-19 Javad Rafiei Asl , Prajwal Panzade , Eduardo Blanco , Daniel Takabi , Zhipeng Cai