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This study investigates the behaviors of Large Language Models (LLMs) when faced with conflicting prompts versus their internal memory. This will not only help to understand LLMs' decision mechanism but also benefit real-world applications,…

Computation and Language · Computer Science 2024-02-21 Jiahao Ying , Yixin Cao , Kai Xiong , Yidong He , Long Cui , Yongbin Liu

As large language models (LLMs) become more powerful and are deployed more autonomously, it will be increasingly important to prevent them from causing harmful outcomes. Researchers have investigated a variety of safety techniques for this…

Machine Learning · Computer Science 2024-07-24 Ryan Greenblatt , Buck Shlegeris , Kshitij Sachan , Fabien Roger

Following multiple instructions is a crucial ability for large language models (LLMs). Evaluating this ability comes with significant challenges: (i) limited coherence between multiple instructions, (ii) positional bias where the order of…

Computation and Language · Computer Science 2025-12-12 Xinyi Chen , Baohao Liao , Jirui Qi , Panagiotis Eustratiadis , Christof Monz , Arianna Bisazza , Maarten de Rijke

Large Language Models (LLMs) have demonstrated promise in medical knowledge assessments, yet their practical utility in real-world clinical decision-making remains underexplored. In this study, we evaluated the performance of three…

Computation and Language · Computer Science 2025-12-30 Mengdi Chai , Ali R. Zomorrodi

Language models that can learn a task at inference time, called in-context learning (ICL), show increasing promise in natural language inference tasks. In ICL, a model user constructs a prompt to describe a task with a natural language…

Software Engineering · Computer Science 2024-04-22 Sarah Santos , Travis Breaux , Thomas Norton , Sara Haghighi , Sepideh Ghanavati

One of the most common complaints about large language models (LLMs) is their prompt sensitivity -- that is, the fact that their ability to perform a task or provide a correct answer to a question can depend unpredictably on the way the…

Large language models (LLMs) are increasingly applied in educational, clinical, and professional settings, but their tendency for sycophancy -- prioritizing user agreement over independent reasoning -- poses risks to reliability. This study…

Artificial Intelligence · Computer Science 2025-09-22 Aaron Fanous , Jacob Goldberg , Ank A. Agarwal , Joanna Lin , Anson Zhou , Roxana Daneshjou , Sanmi Koyejo

This study reveals a previously unexplored vulnerability in the safety alignment of Large Language Models (LLMs). Existing aligned LLMs predominantly respond to unsafe queries with refusals, which often begin with a fixed set of prefixes…

Cryptography and Security · Computer Science 2026-01-28 Yangyang Guo , Ziwei Xu , Si Liu , Zhiming Zheng , Mohan Kankanhalli

When the substantive content of a request is rewritten, do large language models still answer in the format the original task asked for? We find that they often do not, even at temperature zero. On a 150-query evaluation over five compact…

Computation and Language · Computer Science 2026-05-12 Aofan Liu , Jingxiang Meng

The advent of instruction-tuned Large Language Models designed for coding tasks (Code LLMs) has transformed software engineering practices. However, their robustness against various input challenges remains a critical concern. This study…

Software Engineering · Computer Science 2024-12-02 Md Imran Hossen , Xiali Hei

Instruction-tuned Large Language Models (LLMs) have achieved remarkable performance across various benchmark tasks. While providing instructions to LLMs for guiding their generations is user-friendly, assessing their instruction-following…

Computation and Language · Computer Science 2024-06-25 Rem Hida , Junki Ohmura , Toshiyuki Sekiya

Large language models (LLMs) have shown remarkable performance in various tasks and have been extensively utilized by the public. However, the increasing concerns regarding the misuse of LLMs, such as plagiarism and spamming, have led to…

Computation and Language · Computer Science 2024-05-16 Ning Lu , Shengcai Liu , Rui He , Qi Wang , Yew-Soon Ong , Ke Tang

Large Language Models (LLMs) are increasingly applied to automate software engineering tasks, including the generation of UML class diagrams from natural language descriptions. While prior work demonstrates that LLMs can produce…

Software Engineering · Computer Science 2026-04-07 Rabia Iftikhar , Andreas Rausch

We present and evaluate a suite of proof-of-concept (PoC), structured workflow prompts designed to elicit human-like hierarchical reasoning while guiding Large Language Models (LLMs) in the high-level semantic and linguistic analysis of…

Computation and Language · Computer Science 2025-06-18 Evgeny Markhasin

Large language models are trained to refuse harmful requests, but can they accurately predict when they will refuse before responding? We investigate this question through a systematic study where models first predict their refusal…

Computation and Language · Computer Science 2026-04-02 Tanay Gondil

Instruction fine-tuning (IFT) elicits instruction following capabilities and steers the behavior of large language models (LLMs) via supervised learning. However, existing models trained on open-source IFT datasets only have the ability to…

Computation and Language · Computer Science 2024-09-24 Kuan Wang , Alexander Bukharin , Haoming Jiang , Qingyu Yin , Zhengyang Wang , Tuo Zhao , Jingbo Shang , Chao Zhang , Bing Yin , Xian Li , Jianshu Chen , Shiyang Li

System prompts provide a lightweight yet powerful mechanism for conditioning large language models (LLMs) at inference time. While prior work has focused on English-only settings, real-world deployments benefit from having a single prompt…

Computation and Language · Computer Science 2025-12-03 Lechen Zhang , Yusheng Zhou , Tolga Ergen , Lajanugen Logeswaran , Moontae Lee , David Jurgens

Large Language Models (LLMs) increasingly use persistent memory from past interactions to enhance personalization and task performance. However, this memory introduces critical risks when sensitive information is revealed in inappropriate…

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

While defenses against single-turn jailbreak attacks on Large Language Models (LLMs) have improved significantly, multi-turn jailbreaks remain a persistent vulnerability, often achieving success rates exceeding 70% against models optimized…

Machine Learning · Computer Science 2025-08-12 Xiaoxue Yang , Jaeha Lee , Anna-Katharina Dick , Jasper Timm , Fei Xie , Diogo Cruz
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