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Machine learning (ML) tools such as encoder-decoder convolutional neural networks (CNN) can represent incredibly complex nonlinear functions which map between combinations of images and scalars. For example, CNNs can be used to map…

Machine Learning · Computer Science 2021-10-27 Alexander Scheinker

We propose a novel method that performs adaptive clustering with DPMM using collapsed VI, while incorporating weakly-informative priors for DP concentration parameter alpha and base distribution G0. We illustrate the importance of G0…

Methodology · Statistics 2026-02-19 Annesh Pal , Aguirre Mimoun , Rodolphe Thiébaut , Boris P. Hejblum

The growing number of dimensionality reduction methods available for data visualization has recently inspired the development of quality assessment measures, in order to evaluate the resulting low-dimensional representation independently…

Machine Learning · Computer Science 2011-10-19 Wouter Lueks , Bassam Mokbel , Michael Biehl , Barbara Hammer

In this paper, the existing Scheduling Dimension Reduction (SDR) methods for Linear Parameter-Varying (LPV) models are reviewed and a Deep Neural Network (DNN) approach is developed that achieves higher model accuracy under scheduling…

Systems and Control · Electrical Eng. & Systems 2020-12-10 P. J. W. Koelewijn , R. Tóth

Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological assessment as well as localized readouts that can be aligned…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Konstantin Hemker , Andrew H. Song , Cristina Almagro-Pérez , Guillaume Jaume , Sophia J. Wagner , Anurag Vaidya , Nikola Simidjievski , Mateja Jamnik , Faisal Mahmood

Sparse autoencoders (SAEs) have been applied to large language models and protein language models, but not systematically to electronic health record (EHR) foundation models. We train TopK SAEs on FlatASCEND, a 14.5-million-parameter…

Machine Learning · Computer Science 2026-05-07 Chris Sainsbury , Feng Dong , Andreas Karwath

Dimensionality reduction is a crucial step for pattern recognition and data mining tasks to overcome the curse of dimensionality. Principal component analysis (PCA) is a traditional technique for unsupervised dimensionality reduction, which…

Machine Learning · Computer Science 2017-05-04 Zan Gao , Guotai Zhang , Feiping Nie , Hua Zhang

An efficient computational approach for optimal reconstruction of binary-type images suitable for models in various applications including biomedical imaging is developed and validated. The methodology includes derivative-free optimization…

Optimization and Control · Mathematics 2022-09-27 Paul R. Arbic , Vladislav Bukshtynov

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

Sparse autoencoders (SAEs) are one of the main methods to interpret the inner workings of deep neural networks (DNNs), decomposing activations into higher-dimensional features. However, they exhibit critical shortcomings where a large…

Machine Learning · Computer Science 2026-05-19 Michał Brzozowski , Neo Christopher Chung

Real-time data collection and analysis in large experimental facilities present a great challenge across multiple domains, including high energy physics, nuclear physics, and cosmology. To address this, machine learning (ML)-based methods…

Machine Learning · Computer Science 2021-11-11 Yi Huang , Yihui Ren , Shinjae Yoo , Jin Huang

Creating large datasets of medical radiology images from several sources can be challenging because of the differences in the acquisition and storage standards. One possible way of controlling and/or assessing the image selection process is…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Teo Manojlović , Matija Milanič , Ivan Štajduhar

We propose a new framework of variance-reduced Hamiltonian Monte Carlo (HMC) methods for sampling from an $L$-smooth and $m$-strongly log-concave distribution, based on a unified formulation of biased and unbiased variance reduction…

Machine Learning · Computer Science 2021-02-10 Zhengmian Hu , Feihu Huang , Heng Huang

Recently, a number of works have studied clustering strategies that combine classical clustering algorithms and deep learning methods. These approaches follow either a sequential way, where a deep representation is learned using a deep…

Machine Learning · Computer Science 2019-06-13 Severine Affeldt , Lazhar Labiod , Mohamed Nadif

Clustering short text embeddings is a foundational task in natural language processing, yet remains challenging due to the need to specify the number of clusters in advance. We introduce a scalable spectral method that estimates the number…

Machine Learning · Computer Science 2025-11-26 Nikita Neveditsin , Pawan Lingras , Vijay Mago

In surface defect detection, due to the extreme imbalance in the number of positive and negative samples, positive-samples-based anomaly detection methods have received more and more attention. Specifically, reconstruction-based methods are…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Wei Luo , Tongzhi Niu , Lixin Tang , Wenyong Yu , Bin Li

Evaluating LLMs and text-to-image models is a computationally intensive task often overlooked. Efficient evaluation is crucial for understanding the diverse capabilities of these models and enabling comparisons across a growing number of…

Randomized algorithms can be used to speed up the analysis of large datasets. In this paper, we develop a unified methodology for statistical inference via randomized sketching or projections in two of the most fundamental problems in…

Statistics Theory · Mathematics 2024-04-02 Leda Wang , Zhixiang Zhang , Edgar Dobriban

Clinical MRI encompasses diverse imaging protocols--spanning anatomical targets (cardiac, brain, knee), contrasts (T1, T2, mapping), sampling patterns (Cartesian, radial, spiral, kt-space), and acceleration factors--yet current deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Puyang Wang , Pengfei Guo , Keyi Chai , Jinyuan Zhou , Daguang Xu , Shanshan Jiang

Analyzing and visualizing scientific ensemble datasets with high dimensionality and complexity poses significant challenges. Dimensionality reduction techniques and autoencoders are powerful tools for extracting features, but they often…

Machine Learning · Computer Science 2026-01-19 Hamid Gadirov , Lennard Manuel , Steffen Frey