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High-dimensional tensors or multi-way data are becoming prevalent in areas such as biomedical imaging, chemometrics, networking and bibliometrics. Traditional approaches to finding lower dimensional representations of tensor data include…

Machine Learning · Statistics 2012-02-14 Genevera I. Allen

Topological data analysis (TDA) has emerged as one of the most promising techniques to reconstruct the unknown shapes of high-dimensional spaces from observed data samples. TDA, thus, yields key shape descriptors in the form of persistent…

Machine Learning · Statistics 2017-11-15 Wei Guo , Krithika Manohar , Steven L. Brunton , Ashis G. Banerjee

Spatial Transcriptomics enables mapping of gene expression within its native tissue context, but current platforms measure only a limited set of genes due to experimental constraints and excessive costs. To overcome this, computational…

Genomics · Quantitative Biology 2025-11-20 Amit Kumar , Maninder Kaur , Raghvendra Mall , Sukrit Gupta

Subspace clustering refers to the problem of clustering high-dimensional data into a union of low-dimensional subspaces. Current subspace clustering approaches are usually based on a two-stage framework. In the first stage, an affinity…

Machine Learning · Computer Science 2019-10-22 Shuai Yang , Wenqi Zhu , Yuesheng Zhu

Spatial Transcriptomics is a novel technology that aligns histology images with spatially resolved gene expression profiles. Although groundbreaking, it struggles with gene capture yielding high corruption in acquired data. Given potential…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Gabriel Mejia , Daniela Ruiz , Paula Cárdenas , Leonardo Manrique , Daniela Vega , Pablo Arbeláez

Widely used traditional pipelines for subcortical brain segmentation are often inefficient and slow, particularly when processing large datasets. Furthermore, deep learning models face challenges due to the high resolution of MRI images and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Aaron Cao , Zongyu Li , Jordan Jomsky , Andrew F. Laine , Jia Guo

Convolutional neural networks (CNNs) have become increasingly difficult to deploy in resource-constrained environments due to their large memory and computational requirements. Although low-rank compression methods can reduce this burden,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Sisipho Hamlomo , Marcellin Atemkeng , Habte Tadesse Likassa , Blaise Ravelo , Thierry Bouwmans , Sébastien Lalléchère , Antoine Vacavant , Ding-Geng Chen

Driven by a wide range of applications, many principal subspace estimation problems have been studied individually under different structural constraints. This paper presents a unified framework for the statistical analysis of a general…

Statistics Theory · Mathematics 2020-11-17 T. Tony Cai , Hongzhe Li , Rong Ma

Sequence classification has numerous applications in various fields. Despite extensive studies in the last decades, many challenges still exist, particularly in pattern-based methods. Existing pattern-based methods measure the…

Machine Learning · Computer Science 2023-10-23 Junjie Dong , Mudi Jiang , Lianyu Hu , Zengyou He

Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Yupei Zhang , Xiaofei Wang , Anran Liu , Lequan Yu , Chao Li

Contrastive dimension reduction (CDR) methods aim to extract signal unique to or enriched in a treatment (foreground) group relative to a control (background) group. This setting arises in many scientific domains, such as genomics, imaging,…

Methodology · Statistics 2025-10-15 Sam Hawke , Eric Zhang , Jiawen Chen , Didong Li

Deep learning models hold state of the art performance in many fields, yet their design is still based on heuristics or grid search methods that often result in overparametrized networks. This work proposes a method to analyze a trained…

Computer Vision and Pattern Recognition · Computer Science 2020-01-13 Isha Garg , Priyadarshini Panda , Kaushik Roy

Imaging modalities such as Computed Tomography (CT) and Positron Emission Tomography (PET) are key in cancer detection, inspiring Deep Neural Networks (DNN) models that merge these scans for tumor segmentation. When both CT and PET scans…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Nada Saadi , Numan Saeed , Mohammad Yaqub , Karthik Nandakumar

The joint optimization of the reconstruction and classification error is a hard non convex problem, especially when a non linear mapping is utilized. In order to overcome this obstacle, a novel optimization strategy is proposed, in which a…

Machine Learning · Computer Science 2022-11-07 Ioannis A. Nellas , Sotiris K. Tasoulis , Vassilis P. Plagianakos , Spiros V. Georgakopoulos

During the last decade, hyperspectral images have attracted increasing interest from researchers worldwide. They provide more detailed information about an observed area and allow an accurate target detection and precise discrimination of…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Asma Elmaizi , Hasna Nhaila , Elkebir Sarhrouni , Ahmed Hammouch , Nacir Chafik

Parameterizable machine learning (ML) accelerators are the product of recent breakthroughs in ML. To fully enable their design space exploration (DSE), we propose a physical-design-driven, learning-based prediction framework for…

Large-scale multimodal contrastive learning has recently achieved impressive success in learning rich and transferable representations, yet it remains fundamentally limited by the uniform treatment of feature dimensions and the neglect of…

Machine Learning · Computer Science 2026-02-11 Jinjin Guo , Yexin Li , Zhichao Huang , Jun Fang , Zhiyuan Liu , Chao Liu , Pengzhang Liu , Qixia Jiang

Recently, numerous learning-based compression methods have been developed with outstanding performance for the coding of the geometry information of point clouds. On the contrary, limited explorations have been devoted to point cloud…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Jianqiang Wang , Zhan Ma

We developed a deep ensemble learning model with a radiomics spatial encoding execution for improved glioma segmentation accuracy using multi-parametric MRI (mp-MRI). This model was developed using 369 glioma patients with a 4-modality…

Quantitative Methods · Quantitative Biology 2023-03-21 Yang Chen , Zhenyu Yang , Jingtong Zhao , Justus Adamson , Yang Sheng , Fang-Fang Yin , Chunhao Wang

Dimension reduction is often the first step in statistical modeling or prediction of multivariate spatial data. However, most existing dimension reduction techniques do not account for the spatial correlation between observations and do not…

Methodology · Statistics 2025-05-27 Si Cheng , Magali N. Blanco , Timothy V. Larson , Lianne Sheppard , Adam Szpiro , Ali Shojaie