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Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…
We report an angle-tilted, wavelength-multiplexed ptychographic modulation approach for multispectral lensless on-chip microscopy. In this approach, we illuminate the specimen with lights at 5 wavelengths simultaneously. A prism is added at…
The traditional wisdom for achieving transparency is to minimize disordered scattering within and on the surface of materials, so as to avoid translucency. However, the lack of disordered scattering also deprives the possibility of…
Spectral differences between lensed quasar image components are common. Since lensing is intrinsically achromatic, these differences are typically explained as the effect of either microlensing, or as light path time delays sampling…
Since the first detection of gravitational waves in 2015, gravitational-wave astronomy has emerged as a rapidly advancing field that holds great potential for studying the cosmos, from probing the properties of black holes to testing the…
Inhomogeneities in the refractive index of a biological sample can introduce phase aberrationsin microscopy systems, severely impairing the quality of images. Adaptive optics can be employed to correct for phase aberrations and improve…
Optical imaging deep inside scattering media remains a fundamental problem in bio-imaging. While wavefront shaping has been shown to allow focusing of coherent light at depth, achieving it non-invasively remains a challenge. Various…
Wide-angle optical functionality is crucial for implementation of advanced imaging and image projection devices. Conventionally, wide-angle operation is attained by complicated assembly of multiple optical elements. Recent advances in…
Correlative computational microscopy can accelerate imaging and modeling of cellular dynamics by relaxing trade-offs inherent to dynamic imaging. Existing computational microscopy frameworks are either specialized or overly generic,…
The small correction volume for conventional wavefront shaping methods limits their applications in biological imaging through scattering media. We demonstrate large volume wavefront shaping through a scattering layer with a single…
Sensing and manipulating targets hidden under scattering media are universal problems that take place in applications ranging from deep-tissue optical imaging to laser surgery. A major issue in these applications is the shallow light…
Starting from well-known absolute instruments for perfect imaging, we introduce a type of rotational-symmetrical compact closed manifolds, namely geodesic lenses. We demonstrate that light rays confined on geodesic lenses are closed…
We describe the apparatus of a fluorescence optical microscope with both single-photon and two-photon non-diffracting light sheets excitation for large volume imaging. With special design to accommodate two different wavelength ranges…
Ultrathin and flat optical lenses are essential for modern optical imaging, spectroscopy, and energy harvesting. Dielectric metasurfaces comprising nanoscale quasi-periodic resonator arrays are promising for such applications, as they can…
In optical devices like diffraction gratings and Fresnel lenses, light wavefront is engineered through the structuring of device surface morphology, within thicknesses comparable to the light wavelength. Fabrication of such diffractive…
A metasurface lens (meta-lens) bends light using nanostructures on a flat surface. Macroscopic meta-lenses (mm- to cm-scale diameter) have been quite difficult to simulate and optimize, due to the large area, the lack of periodicity, and…
On the quest towards full control over wave propagation, the development of compact devices that allow asymmetric response is a challenge. In this Letter, we introduce a new paradigm for the engineering of asymmetry in planar structures,…
Label-free microscopy exploits light scattering to obtain a three-dimensional image of biological tissues. However, light propagation is affected by aberrations and multiple scattering, which drastically degrade the image quality and limit…
The thin and flexible nature of optical fibres often makes them the ideal technology to view biological processes in-vivo, but current microendoscopic approaches are limited in spatial resolution. Here, we demonstrate a new route to high…
Metasurface lenses are miniature flat lenses that can precisely control the phase, amplitude, and polarization of incident light by modulating the parameters of each unit on the substrate. Compared with conventional optical lenses, they…