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Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

In healthcare, clinical risks are crucial for treatment decisions, yet the analysis of their associations is often overlooked. This gap is particularly significant when balancing risks that are weighed against each other, as in the case of…

Applications · Statistics 2024-06-03 Yajie Duan , Javier Cabrera , Davit Sargsyan

Deep learning for medical imaging is hampered by task-specific models that lack generalizability and prognostic capabilities, while existing 'universal' approaches suffer from simplistic conditioning and poor medical semantic understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Numan Saeed , Tausifa Jan Saleem , Fadillah Maani , Muhammad Ridzuan , Hu Wang , Mohammad Yaqub

Remote sensing (RS) image-text retrieval plays a critical role in understanding massive RS imagery. However, the dense multi-object distribution and complex backgrounds in RS imagery make it difficult to simultaneously achieve fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Xi Chen , Xu Chen , Xiangyang Jia , Xu Zhang , Shuquan Wei , Wei Wang

Glaucoma is one of the leading causes of irreversible blindness. Segmentation of optic disc (OD) and optic cup (OC) on fundus images is a crucial step in glaucoma screening. Although many deep learning models have been constructed for this…

Image and Video Processing · Electrical Eng. & Systems 2023-04-11 Ziyang Chen , Yongsheng Pan , Yong Xia

Optical coherence tomography (OCT) based measurements of retinal layer thickness, such as the retinal nerve fibre layer (RNFL) and the ganglion cell with inner plexiform layer (GCIPL) are commonly used for the diagnosis and monitoring of…

Computer Vision and Pattern Recognition · Computer Science 2019-10-25 Stefan Maetschke , Bhavna Antony , Hiroshi Ishikawa , Gadi Wollstein , Joel S. Schuman , Rahil Garnavi

Despite the impressive performance of recent unbiased Scene Graph Generation (SGG) methods, the current debiasing literature mainly focuses on the long-tailed distribution problem, whereas it overlooks another source of bias, i.e., semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Shuzhou Sun , Shuaifeng Zhi , Qing Liao , Janne Heikkilä , Li Liu

We describe a new approach to automated Glaucoma detection in 3D Spectral Domain Optical Coherence Tomography (OCT) optic nerve scans. First, we gathered a unique and diverse multi-ethnic dataset of OCT scans consisting of glaucoma and…

Survival prediction plays a crucial role in assisting clinicians with the development of cancer treatment protocols. Recent evidence shows that multimodal data can help in the diagnosis of cancer disease and improve survival prediction.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ruiquan Ge , Xiangyang Hu , Rungen Huang , Gangyong Jia , Yaqi Wang , Renshu Gu , Changmiao Wang , Elazab Ahmed , Linyan Wang , Juan Ye , Ye Li

In this paper, we have proposed a new glaucoma classification approach that employs a wavelet neural network (WNN) on optimally enhanced retinal images features. To avoid tedious and error prone manual analysis of retinal images by…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 N. Krishna Santosh , Soubhagya Sankar Barpanda

Longitudinal medical images are essential for monitoring disease progression by capturing spatiotemporal changes associated with dynamic biological processes. While current methods have made progress in modeling spatiotemporal patterns,…

Quantitative Methods · Quantitative Biology 2025-09-15 Shuaitong Zhang , Yuchen Sun , Yong Ao , Xuehuan Zhang , Ruoshui Yang , Jiantao Xu , Zuwu Ai , Haike Zhang , Xiang Yang , Yao Xu , Kunwei Li , Duanduan Chen

Glaucoma is a serious ocular disorder for which the screening and diagnosis are carried out by the examination of the optic nerve head (ONH). The color fundus image (CFI) is the most common modality used for ocular screening. In CFI, the…

Image and Video Processing · Electrical Eng. & Systems 2019-02-05 Sharath M Shankaranarayana , Keerthi Ram , Kaushik Mitra , Mohanasankar Sivaprakasam

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

When fitting statistical models, some predictors are often found to be correlated with each other, and functioning together. Many group variable selection methods are developed to select the groups of predictors that are closely related to…

Methodology · Statistics 2021-03-25 Zhiyuan Li

Deep learning has significantly advanced automatic medical diagnostics and released the occupation of human resources to reduce clinical pressure, yet the persistent challenge of data scarcity in this area hampers its further improvements…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Zehui Zhao , Laith Alzubaidi , Jinglan Zhang , Ye Duan , Usman Naseem , Yuantong Gu

Alzheimer's disease is a progressive neurodegenerative disorder that remains challenging to predict due to its multifactorial etiology and the complexity of multimodal clinical data. Accurate forecasting of clinically relevant biomarkers,…

Machine Learning · Computer Science 2026-02-03 Yilang Ding , Jiawen Ren , Jiaying Lu , Gloria Hyunjung Kwak , Armin Iraji , Shengpu Tang , Alex Fedorov

Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Chengying She , Chengwei Chen , Xinran Zhang , Ben Wang , Lizhuang Liu , Chengwei Shao , Yun Bian

Fairness (also known as equity interchangeably) in machine learning is important for societal well-being, but limited public datasets hinder its progress. Currently, no dedicated public medical datasets with imaging data for fairness…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Yan Luo , Yu Tian , Min Shi , Louis R. Pasquale , Lucy Q. Shen , Nazlee Zebardast , Tobias Elze , Mengyu Wang

Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of preventable blindness among working-age adults. Traditional approaches in the literature focus on standard color fundus photography (CFP) for the detection of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Pablo Jimenez-Lizcano , Sergio Romero-Tapiador , Ruben Tolosana , Aythami Morales , Guillermo González de Rivera , Ruben Vera-Rodriguez , Julian Fierrez

Precise segmentation of retinal arteries and veins carries the diagnosis of systemic cardiovascular conditions. However, standard convolutional architectures often yield topologically disjointed segmentations, characterized by gaps and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Iftekhar Ahmed , Shakib Absar , Aftar Ahmad Sami , Shadman Sakib , Debojyoti Biswas , Seraj Al Mahmud Mostafa
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